Publications by authors named "Marc Steffen Schmitz-Valckenberg"
Article Synopsis
- The study compares the grading of two types of retinal atrophy (complete and incomplete) using two different imaging techniques: spectral domain optical coherence tomography (SD-OCT) and swept-source OCT angiography (SS-OCTA).
- Findings reveal a 99.6% agreement in grading complete retinal lesions between the two methods, but a notable discrepancy in the assessment of incomplete retinal atrophy, where 27.4% of these lesions were found within areas of persistent choroidal hypertransmission defects.
- The study emphasizes the importance of using high-quality B-scans and en face OCT imaging to improve the accuracy of diagnosing retinal conditions and understanding the extent of retinal damage.
Background/purpose: Anti-vascular endothelial growth factor therapies have proven effective in treating retinal diseases but come with a high financial burden to the patient and health care system. Biosimilar drugs present an opportunity to decrease the cost of these important ophthalmic medications, and several ophthalmic biosimilars are expected to be approved and enter the market in the coming years. The objectives of this review are to educate ophthalmologists on the safety and efficacy of biosimilars in ophthalmology in the United States and European Union, review the biosimilar manufacturing and approval process, and describe the upcoming ophthalmic biosimilars.
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