The effect of tablet-based multimodal training on cognitive functioning in Alzheimer's disease: A randomized controlled trial.

Background: Computerized cognitive training conducted in a home setting has shown beneficial effects on cognitive functions in people with mild cognitive impairment. Similar effects in people suffering from Alzheimer's disease (AD) have not yet been found. We aimed to examine the effect of a six-month tablet-based multimodal training in community-dwelling people with mild to moderate AD on cognitive functions and on the volume of (sub)cortical structures.

Interdisciplinary Approach to Structured Forms and Decision Support in Elderly Care.

Geriatric patients present characteristics specific to this stage of life, that require targeted care. Health information technologies have the potential to improve the quality of healthcare. The objective of this study is to describe the design of a mobile and web application for the comprehensive care of older adults.

Assessing the Efficacy and Safety of the Allurion Gastric Balloon in Latin American Patients: A Multicenter Case Series.

The Allurion gastric balloon (AGB) is an innovative option for treating overweight individuals and those with grade I obesity, or as a bridging treatment for bariatric surgery, or for patients who do not desire surgical intervention. This study aimed to evaluate the efficacy and safety of the AGB in a multicentric cohort. A retrospective analysis of consecutive cases treated with AGB (≥18 years old with body mass index [BMI] ≥27) was performed in eight centers in three countries in Latin America (Argentina, Chile, and Perú), between September 2021 and September 2022, with a 12-month follow-up.

Association of intraoperative hypotension and acute kidney injury in noncardiac surgery patients: a post hoc secondary analysis of the EU HYPROTECT registry.

Purpose: Previous cohort studies suggest that intraoperative hypotension is associated with acute kidney injury (AKI) in noncardiac surgical patients. We sought to ascertain that intraoperative hypotension is independently associated with AKI within the first 3 days after surgery in a contemporary cohort of noncardiac surgery patients in whom clinicians strove to avoid profound intraoperative hypotension.

Methods: This was a post hoc secondary analysis of the multicentre EU HYPROTECT registry, which includes patients undergoing major noncardiac surgery who underwent predictive blood pressure monitoring.

Brugada Phenocopy in a Critical Obstetric Patient: A Case Report.

Brugada phenocopy (BrP) is an electrocardiographic (ECG) alteration that mimics Brugada syndrome (BrS) but lacks the associated genetic predisposition. It manifests as a transient pattern induced by reversible factors such as electrolyte imbalances, internal environment disturbances, and the use of certain drugs. In critically ill patients, hyperkalemia and acidosis are common triggers of this phenomenon, affecting ventricular repolarization and generating an ECG pattern identical to BrS.

SARS-CoV-2 post-acute sequelae linked to inflammation via extracellular vesicles.

Background: Despite the efficacy of SARS-CoV-2 vaccines in reducing mortality and severe cases of COVID-19, a proportion of survivors experience long-term symptoms, known as post-acute sequelae of SARS-CoV-2 infection (PASC). This study investigates the long-term immunological and neurodegenerative effects associated with extracellular vesicles (EVs) in COVID-19 survivors, 15 months after SARS-CoV-2 infection.

Methods: 13 Controls and 20 COVID-19 survivors, 15 months after SARS-CoV-2 infection, were recruited.

Cardiac Remodeling after Bariatric Surgery Beyond Weight Loss: A Dose-Response Analysis.

Background: Obesity is associated with deleterious metabolic and hemodynamic changes resulting in cardiac remodeling. Bariatric surgery is highly effective for both weight reduction and reverse cardiac remodeling. However, whether these changes depend on the magnitude of weight loss is unknown.

Increasing STI and HIV Preventive Behaviors and Addressing Community-Prioritized Social Determinants of Health Among Young GBQMSM and Transgender Women of Color: Piloting a Bilingual Multilevel Intervention.

Background: Sexually transmitted infections (STIs) and HIV disproportionately affect young people; gay, bisexual, queer, and other men who have sex with men (GBQMSM); transgender women; and persons of color. Our community-based participatory research partnership developed and implemented Impact Triad, a bilingual multilevel intervention harnessing peer navigation and mHealth to increase STI/HIV preventive behaviors and address 4 community-prioritized social determinants of health-education, employment, social support, and discrimination-among young African American/Black and Latine GBQMSM and transgender women.

Methods: Fifteen community-based peer navigators were trained to work within their social networks for 12 months.

Perspectives of the COVID-19 pandemic and vaccination among racially and ethnically diverse gay, bisexual, and other men who have sex with men with and without HIV in the US South: findings from qualitative individual in-depth interviews.

Background: The impact of COVID-19 on specific populations, including gay, bisexual, and other men who have sex with men (GBMSM), varies based on a range of factors such as access to health care, underlying health behaviors and conditions, and social determinants of health. Our community-based participatory research partnership sought to better understand perspectives about and experiences with the COVID-19 pandemic, COVID-19 vaccination, and related health care among GBMSM.

Methods: We collected, analyzed, and interpreted qualitative in-depth interview data from a diverse sample of GBMSM (N = 30) in North Carolina, USA.

HIV Testing and PrEP Use Among Trans and/or Non-binary Participants in the TASG Study, a Participatory Study in Germany.

HIV testing and pre-exposure prophylaxis (PrEP) are recommended in Germany for individuals at increased HIV risk. However, data on HIV testing, PrEP use, and PrEP knowledge among trans and non-binary people are limited. We analysed data from the 'Sexuelle Gesundheit in trans und nicht-binären Communitys' (TASG) study, a participatory study on HIV/STI and sexual health among trans and non-binary people in Germany.

Weight Loss and Regain After Bariatric Surgery: Importance of the Psychological Therapy in Postoperative Outcomes.

Background: Obesity is a chronic disease constituting a public health issue, and its prevalence is alarmingly on the rise worldwide. This disease represents a chronic and multifactorial condition, one of the factors being related to the psychological aspect of the patients. Bariatric is an effective tool for obesity control, with weight regain observed more frequently between the third and sixth postoperative years.

Erratum: Burden of disease attributable to high body mass index: an analysis of data from the Global Burden of Disease Study 2021.

[This corrects the article DOI: 10.1016/j.eclinm.

Transgender Latinas' Perspectives on HIV PrEP Uptake, Condom Use, and Medically Supervised Gender-Affirming Hormone Therapy: Insights From ChiCAS Qualitative Interviews.

There is a dearth of HIV prevention behavioral interventions for transgender Latinas, despite this population's HIV risk. ChiCAS (Chicas Creando Acceso a la Salud) is an intervention to increase PrEP, condom, and gender-affirming hormone therapy (GAHT) use among transgender Latinas. To inform future work, semistructured interviews were conducted postintervention with 28 ChiCAS participants.

Environmental effects on abundance and size of harvested bivalve populations in intertidal shellfish grounds.

Clams, razor clams and cockle are intertidal bivalve species collected on foot in the shellfish grounds of the Rías Altas (NW Spain). Spatio-temporal distribution of these bivalves are typically at the expenses of the environmental conditions of the region; however, the responses to the abiotic conditions are poorly understood. Using data from 6 species (Ruditapes decussatus, Venerupis corrugata, Ruditapes philippinarum, Cerastoderam edule, Donax trunculus and Solen marginatus) sampled in 51 intertidal shellfish grounds during 2007 and 2008, we characterized the influence of the environment (temperature, salinity, nutrient salts, suspended organic matter, or sediment granulometry and composition) on the distribution and size of these species through a comparative statistical analysis.

The Role of Stigma and Resilience in Healthcare Engagement Among Transgender Latinas in the U.S. South: Baseline Findings from the ChiCAS Study.

Research demonstrates that stigma and resilience influence transgender peoples' healthcare use. Less is known about transgender Latinas in the U.S.

The Lure of the Podium: The Seductive Appeal of Predatory Conference Speaker Invitations.

This letter highlights an escalating concern regarding predatory conference speaker invitations that are currently plaguing academia. Such invitations are frequently issued to individuals outside their areas of expertise, for instance, non-healthcare professionals being invited to health-related conferences. This issue poses a substantial threat as it compromises the integrity of legitimate academic discourse and carries the risk of propagating unchecked and potentially detrimental information.

Understanding uptake of COVID-19 testing, vaccination, and boosters among Spanish-speaking Latines in the United States: Qualitative insights from Spanish speakers and key informants.

Background: Latine communities in the United States have been disproportionately affected by COVID-19. It is critical to gain a better understanding of the sociocultural determinants that challenge and facilitate COVID-19 testing, vaccination, and booster uptake within these vulnerable communities to inform culturally congruent strategies and interventions.

Methods: In summer 2022, our community-based participatory research partnership conducted 30 key informant interviews and 7 focus groups with 64 Spanish-speaking Latine participants in North Carolina.

Novel Entropy-Based Metrics for Long-Term Atrial Fibrillation Recurrence Prediction Following Surgical Ablation: Insights from Preoperative Electrocardiographic Analysis.

Atrial fibrillation (AF) is a prevalent cardiac arrhythmia often treated concomitantly with other cardiac interventions through the Cox-Maze procedure. This highly invasive intervention is still linked to a long-term recurrence rate of approximately 35% in permanent AF patients. The aim of this study is to preoperatively predict long-term AF recurrence post-surgery through the analysis of atrial activity (AA) organization from non-invasive electrocardiographic (ECG) recordings.

Using to Develop a Multicultural Intervention to Reduce Disparities among Sexual and Gender Minorities in Appalachia.

Background: Gay, bisexual, queer, and other men who have sex with men (GBQMSM) and transgender persons in Appalachia are at an increased risk for HIV, sexually transmitted infections (STIs), hepatitis C virus (HCV), mpox (formerly known as monkeypox) and are less likely to use prevention and care services.

Objectives: Our community-based participatory research partnership sought to develop an intervention to increase use of HIV, STI, HCV, and mpox prevention and care services among diverse GBQMSM and transgender and nonbinary persons living in rural Appalachia.

Methods: We used ENGAGED for CHANGE, a novel community-engaged participatory intervention development process, to integrate two evidence-based strategies-community-based peer navigation and mHealth-into a multi-cultural intervention.

Exploring Individual and Contextual Factors Associated With Sexual Risk and Substance Use Among Underserved GBQMSM and Transgender and Nonbinary Persons in South Central Appalachia.

Gay, bisexual, queer, and other men who have sex with men (GBQMSM) and transgender and nonbinary persons are at elevated risk for HIV, sexually transmitted infections (STIs), and hepatitis C (HCV); in Appalachia, these communities experience more disease burden. However, little is known about the factors influencing risk. Sixteen semistructured in-depth interviews were conducted examining factors influencing prevention and care.