Publications by authors named "Manon Boullard"
Article Synopsis
- A new study in the French West Indies examines the connection between chlordecone pesticide soil contamination and cancer rates in Martinique from 2006 to 2019, using a more sensitive contamination indicator.
- This study analyzed data from 23,218 cancer cases, finding that women exposed to higher soil contamination levels showed an increased risk for several cancers, including lung and thyroid cancer, while no significant correlation was observed for breast or prostate cancer.
- The findings suggest that women in Martinique are disproportionately affected by chlordecone exposure, highlighting the need for ongoing research into the environmental impacts of pesticides on public health.
Burden of gastric and digestive cancers in the French Caribbean: perspectives from population-based cancer registries of Martinique, Guadeloupe and French Guiana (2007-2014).
BMJ Open
February 2022
Objectives: Data from population-based cancer registries contribute to improving our knowledge of digestive cancer trends worldwide. In this study, we present cancer incidence and mortality in Guadeloupe, French Guiana and Martinique for the periods 2008-2014, 2010-2014 and 2007-2014, respectively.
Design: Data were extracted from population-based cancer registries.
2,3-Diphenylated quinoxaline, pyrido[2,3-]pyrazine and 8-bromopyrido[3,4-]pyrazine were halogenated in deprotometalation-trapping reactions using mixed 2,2,6,6-tetramethyl piperidino-based lithium-zinc combinations in tetrahydrofuran. The 2,3-diphenylated 5-iodo- quinoxaline, 8-iodopyrido[2,3-]pyrazine and 8-bromo-7-iodopyrido[3,4-]pyrazine thus obtained were subjected to palladium-catalyzed couplings with arylboronic acids or anilines, and possible subsequent cyclizations to afford the corresponding pyrazino[2,3-]carbazole, pyrazino[2',3':5,6] pyrido[4,3-]indole and pyrazino[2',3':4,5]pyrido[2,3-]indole, respectively. 8-Iodopyrido[2,3-] pyrazine was subjected either to a copper-catalyzed C-N bond formation with azoles, or to direct substitution to introduce alkylamino, benzylamino, hydrazine and aryloxy groups at the 8 position.
View Article and Find Full Text PDFPregnancy Outcomes after ZIKV Infection in French Territories in the Americas.
N Engl J Med
March 2018
Background: The risk of congenital neurologic defects related to Zika virus (ZIKV) infection has ranged from 6 to 42% in various reports. The aim of this study was to estimate this risk among pregnant women with symptomatic ZIKV infection in French territories in the Americas.
Methods: From March 2016 through November 2016, we enrolled in this prospective cohort study pregnant women with symptomatic ZIKV infection that was confirmed by polymerase-chain-reaction (PCR) assay.