Endophytic fungi are microorganisms that infect living plant tissues internally without producing obvious symptoms of infection, existing in a symbiotic relationship with plants for a portion of their life cycle. Currently, endophytic fungi serve as alternate sources for the production of new bioactive chemicals with great efficacy. This study aimed to examine the antimigration and anti-invasion capabilities of the endophytic fungus extract, isolated from L.
View Article and Find Full Text PDFThe growing threat of antibiotic resistance in bacteria is a critical public health concern. Combining natural compounds with antimicrobial agents is an alternative approach to improve the antibacterial efficacy and safety of these agents. The strategy is to restore the effectiveness of existing antibiotics while minimizing the required concentrations of antibiotics or antimicrobial agents.
View Article and Find Full Text PDFThe rise in antimicrobial-resistant (AMR) bacteria, especially Methicillin-resistant (MRSA), is a global health concern. Bacteriocins are promising antibiotic alternatives. This study aimed to enhance the production of bacteriocin-like substances (BLS) from SA-14 (TISTR 2453) by optimizing nutrients, evaluating antibacterial activity, assessing synergy with vancomycin, and testing the cytotoxicity and wound healing effects on human keratinocytes.
View Article and Find Full Text PDFCancer metastasis is the primary cause of cancer morbidity and mortality. Anti-metastasis mechanism of skin cancer by 13-butoxyberberine bromide, a novel berberine derivative, has not yet been reported. This study investigated the effects of 13-butoxyberberine bromide on migration and invasion of skin cancer A431 cells.
View Article and Find Full Text PDFAnemia is a global public health problem. The prevalence of anemia among different ages, genders or ethnic groups must be clarified in order to solve problems. This study proposed to determine the prevalence and factors related to anemia among the Muslim school-age population in Nakhon Si Thammarat, Thailand.
View Article and Find Full Text PDFEvid Based Complement Alternat Med
July 2020
Chondrosarcoma is primary bone cancer, with the forceful capacity to cause local invasion and distant metastasis, and has a poor prognosis. Cancer metastasis is a complication of most cancers; it is one of the leading causes of cancer-related death. Rhodomyrtone is a pure compound that has been shown to induce apoptosis and antimetastasis in skin cancer.
View Article and Find Full Text PDFRhodomyrtone is a bioactive compound extracted from leaves. It has been used as a traditional herb medicine for many years. Rhodomyrtone exhibits antibacterial activity, anti-inflammatory and antioxidant activities.
View Article and Find Full Text PDFThis study focused on the inhibitory effect of rhodomyrtone, a bioactive compound isolated from the leaves of Rhodomyrtus tomentosa (Aiton) Hassk., on cancer metastasis in epidermoid carcinoma A431 cells and on the verification of the underlying related molecular mechanisms of this event. We demonstrated that rhodomyrtone at the subcytotoxic concentration (0.
View Article and Find Full Text PDFWorld J Microbiol Biotechnol
August 2014
Liamocins are structurally unique, heavier-than-water “oils” produced by certain strains of Aureobasidium pullulans. The aim of the current study is to identify new sources of liamocins and evaluate their potential as anticancer agents. Nine strains of A.
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