Unravelling the Link Between Body Mass Index and Cognitive Performance in Individuals With Bipolar Disorder and Exploration of PRS Moderation Effect: Findings From the PsyCourse Study.

Introduction: Bipolar disorder (BD) is a severe mental disorder characterized by extreme mood swings, often accompanied by metabolic comorbidities, such as cardiovascular disease, which increase mortality and reduce quality of life. Both metabolic dysfunctions and BD are associated with cognitive dysfunction. Body mass index (BMI) is closely linked to metabolic health and cognitive performance.

Evaluation of Biocontrol Measures to Reduce Bacterial Load and Healthcare-Associated Infections.

Hospital-acquired infections (HAIs) remain a major clinical and economic burden, with pathogens such as Escherichia coli contributing to high rates of morbidity and mortality. Traditional manual disinfection methods are often insufficient, particularly in high-risk hospital environments. In this study, we investigated innovative strategies to enhance surface decontamination and reduce infection risk.

Visuospatial skills and intention attribution: A review of the Object Perspective Taking Test and Santa Barbara Sense of Direction questionnaire with Exploratory graph analysis and applications to autism.

Visual-spatial skills are fundamental for navigating the environment and performing daily activities. Individuals with Autism Spectrum Disorder (ASD) often exhibit atypical perceptual processing, especially regarding complex visual stimuli and visuo-perceptual abilities. This study aims to revise the Object Perspective Taking Test (OPT) and the Santa Barbara Sense of Direction Scale (SBSOD) in the Italian context and to compare visuospatial skills between individuals with Autism Spectrum Disorder (ASD) and individuals from the general population (Control Group; CG).

MALAT1 Expression Is Deregulated in miR-34a Knockout Cell Lines.

Non-coding microRNA-34a (miR-34a) regulates the expression of key factors involved in several cellular processes, such as differentiation, apoptosis, proliferation, cell cycle, and senescence. Deregulation of the expression of these factors is implicated in the onset and progression of several human diseases, including cancer, neurodegenerative disorders, and pathologies associated with viral infections and inflammation. Despite numerous studies, the molecular mechanisms regulated by miR-34a remain to be fully understood.

Unlocking Relief: Investigating the Impact of a Fixed Combination of Acetyl-L-Carnitine and Palmitoylethanolamide on Traumatic Acute Low Back Pain.

Background: Peripheral neuropathies encompass a diverse group of disorders involving peripheral nerve damage, often leading to pain, sensory disturbances, and motor impairments. The etiology is multifactorial, with trauma as a key contributor. The treatment of peripheral neuropathies includes medications targeting the nociceptive component, whereas the neuropathic component is managed with agents such as gabapentinoids or antidepressants, though their prolonged use is limited by significant side effects.