Progestin-induced liver injury in an asymptomatic patient.

We report a case of a female in her mid-40s diagnosed as norethisterone-induced liver injury. Our patient presented to the medical gastroenterology clinic with an incidental finding of progressively increasing transaminases. A detailed evaluation strongly supported our suspicion of progestin-induced liver disease with prompt reversal after discontinuation of norethisterone.

Optimization and extraction kinetic modeling of antioxidants, polyphenols, and flavonoids from and rind.

The optimization for the extraction of bioactive compounds from (GC) and (nutmeg rind (NM)) using Peleg's kinetic model with Response Surface Methodology (RSM) was observed. The extraction efficiency was assessed through Total Phenolic Content (TPC), Total Flavonoids (TF), and Antioxidant activity. The effect of particle size, temperature, and solvent concentration on extraction performance was facilitated by RSM.

Adult Hemolytic Uremic Syndrome as a Diagnostic Challenge.

Hemolytic uremic syndrome (HUS) is a rare but serious condition in adults, typically characterized by a triad of microangiopathic hemolytic anemia (MAHA), thrombocytopenia, and acute kidney injury (AKI). While most commonly associated with pediatric populations and Shiga toxin-producing (STEC), adult-onset cases remain underrecognized, especially in resource-limited settings like India. We report the case of a 35-year-old male patient who presented with a low-grade fever, bloody diarrhea, jaundice, and dark brown-colored urine.

Right atrial myxoma excision with pulmonary thrombectomy.

Myxomas are the most common primary tumors of the heart. Myxomas that are smooth and large usually present with obstructive symptoms whereas the ones that are villous and friable embolize. Due to the risk of mechanical obstruction and embolization, they require immediate surgical intervention.

Tooth morbidity and its impact on oral related quality of life in elderly tribal population-The Irula experience.

Introduction: Oral diseases are a major global health challenge, posing health and economic burdens that have profound impacts on the quality of life, disproportionately affecting marginalized populations such as tribal communities. Among scheduled tribes in India, the Irula community belongs to one of the tribes most vulnerable by poor access to health care and education. The elders in the population have increased incidence and prevalence rates of tooth morbidities-an increased incidence of caries, non-carious lesions, and periodontitis-related conditions that affect oral health related quality of life (OHQOL) dimensions.