Feasibility Trial Protocol for a Remote Intentional Music Listening Intervention to Support Mental Health in Individuals with Chronic Stroke.

Introduction: Post-stroke depression affects approximately 30% of stroke survivors and is linked to worse functional outcomes, cognitive decline, reduced quality of life, and increased mortality. While early treatment of post-stroke mental health conditions is critical, current pharmacological options offer limited efficacy. Music listening interventions are a promising, low-risk, accessible, and affordable alternative that may enhance recovery through engagement of reward-related brain circuits.

Long-term follow-up results of adult atrial septal defect population.

Background: Atrial septal defect (ASD) is a common congenital heart disease (CHD) with significant implications for cardiac function and long-term outcomes in adults. Although ASD often presents in childhood, many cases are diagnosed later in adulthood. Understanding the demographic characteristics, clinical features, and long-term outcomes of adults with ASD is essential for optimizing treatment strategies.

Effect of Iron Deficiency on Right Ventricular Strain in Patients Diagnosed with Acute Heart Failure.

Iron deficiency (ID) is a prevalent comorbidity of heart failure (HF), affecting up to 59% of patients, regardless of the presence of anaemia. Although its negative impact on left ventricular (LV) function is well documented, its effect on right ventricular (RV) function remains unclear. This study assessed the effects of ID on RV global longitudinal strain (RV-GLS) in patients diagnosed with acute decompensated HF (ADHF).

Comorbidity Burden in Chronic Thromboembolic Pulmonary Hypertension: Implications and Outcome.

: Comorbidities, the coexistence of additional conditions with a primary disease, are increasingly prevalent, complicating disease management and clinical outcomes. While CTEPH is a well-studied condition in terms of risk factors and outcomes, the specific impact of comorbidity burden on clinical presentation, treatment decisions, and survival remains insufficiently explored. This study aims to assess the prevalence and burden of comorbidities in CTEPH and to examine their associations with initial clinical characteristics, treatment allocation, and survival, stratified by pulmonary endarterectomy (PEA) status.

The Role of Genetics in Congenital Heart Disease-Associated Pulmonary Arterial Hypertension.

Pulmonary arterial hypertension associated with congenital heart disease (APAH-CHD) is a severely progressive condition with complex pathogenesis. The aim of this study was to evaluate the contribution of genetic variants to the development of PAH in patients with APAH-CHD. Fifteen children and twenty-seven adults diagnosed with APAH-CHD were enrolled.