Publications by authors named "Lynn D Berry"
Article Synopsis
- A study examined the treatment of Idiopathic subglottic stenosis (iSGS) across different medical centers, highlighting the lack of standardization in endoscopic dilation (ED) techniques and treatment outcomes.
- The analysis involved 281 patients from 13 centers and revealed significant differences in procedural methods and recurrence rates, with one group showing a temporary delay in disease recurrence linked to the use of additional medications.
- The findings suggest that more research is needed to explore how these adjuvant therapies impact patient outcomes after ED for iSGS.
Comparative Treatment Outcomes for Idiopathic Subglottic Stenosis: 5-Year Update.
Otolaryngol Head Neck Surg
June 2023
The North American Airway Collaborative (NoAAC) previously published a 3-year multi-institutional prospective cohort study showing variation in treatment effectiveness between 3 primary surgical techniques for idiopathic subglottic stenosis (iSGS). In this report, we update these findings to include 5 years of data evaluating treatment effectiveness. Patients in the NoAAC cohort were re-enrolled for 2 additional years and followed using the prespecified published protocol.
View Article and Find Full Text PDFImpact of Serial Intralesional Steroid Injections on Idiopathic Subglottic Stenosis.
Laryngoscope
September 2023
Article Synopsis
- The study evaluated the effectiveness of Serial Intralesional Steroid Injection (SILSI) for treating idiopathic subglottic stenosis (iSGS) by analyzing outcomes such as time to recurrent operations, peak expiratory flow (PEF), and dyspnea in patients.
- Findings showed no significant differences in recurrence times, PEF, or dyspnea scores between patients who received SILSI and those who only had endoscopic dilation.
- The results suggest the need for a randomized controlled trial to better understand the benefits of SILSI and identify which patients with iSGS might benefit the most from this treatment.
Modeling Recurrence in Idiopathic Subglottic Stenosis With Mobile Peak Expiratory Flow.
Laryngoscope
December 2021
Objectives/hypothesis: We sought to establish normative peak expiratory flow (PEF) data for patients with idiopathic subglottic stenosis (iSGS), evaluate whether immediate changes in PEF after a procedure predict long-term treatment response, and test if a decline in longitudinal PEF is associated with disease recurrence.
Study Design: International, prospective, 3-year multicenter cohort study of 810 patients with untreated, newly diagnosed, or previously treated iSGS.
Methods: iSGS patients consented and enrolled in the North American Airway Collaborative (NoAAC) iSGS cohort recorded PEF data on a mobile smartphone app.
Objectives/hypothesis: Adjuvant medications including proton pump inhibitors (PPI), antibiotics (trimethoprim/sulfamethoxazole [TMP-SMX]), and inhaled corticosteroids (ICS) may be prescribed for patients with idiopathic subglottic stenosis (iSGS). We describe medication use with endoscopic dilation (ED) or endoscopic resection with medical treatment (ERMT) and evaluate impact on outcomes.
Study Design: International, prospective, 3-year multicenter cohort study of 810 patients with untreated, newly diagnosed, or previously treated iSGS.
Association of Social Determinants of Health with Time to Diagnosis and Treatment Outcomes in Idiopathic Subglottic Stenosis.
Ann Otol Rhinol Laryngol
October 2021
Objectives: To examine whether social determinants of health (SDH) factors are associated with time to diagnosis, treatment selection, and time to recurrent surgical intervention in idiopathic subglottic stenosis (iSGS) patients.
Methods: Adult patients with diagnosed iSGS were recruited prospectively (2015-2017) via clinical providers as part of the North American Airway Collaborative (NoAAC) and via an online iSGS support community on Facebook. Patient-specific SDH factors included highest educational attainment (self-reported), median household income (matched from home zip code via U.