Folliculogenesis: A Cellular Crosstalk Mechanism.

In vitro embryo production has accelerated in the cattle industry in recent years. Because women are similar to cows, this represents an opportunity to improve women's reproductive protocols. This review focuses on crosstalk communication during folliculogenesis for an in-depth understanding of the events involved in developing the oocyte competence necessary to generate an embryo after fertilization.

Antineoplastic Activity of Nutt. () against Ovarian Cancer and Identification of Active Metabolites in This Pathology.

(RHTR) is a medicinal plant with cytotoxic activity in different cancer cell lines. However, the active compounds in this plant against ovarian cancer are unknown. In this study, we aimed to evaluate the antineoplastic activity of RHTR and identify its active metabolites against ovarian cancer.

Functional Characterization of the Lin28/let-7 Circuit During Forelimb Regeneration in and Its Influence on Metabolic Reprogramming.

The axolotl () is a caudate amphibian, which has an extraordinary ability to restore a wide variety of damaged structures by a process denominated epimorphosis. While the origin and potentiality of progenitor cells that take part during epimorphic regeneration are known to some extent, the metabolic changes experienced and their associated implications, remain unexplored. However, a circuit with a potential role as a modulator of cellular metabolism along regeneration is that formed by Lin28/let-7.

Linearolactone and Kaempferol Disrupt the Actin Cytoskeleton in : Inhibition of Amoebic Liver Abscess Development.

Linearolactone () and kaempferol () have amebicidal activity in studies. The type of cell death induced by and and their effects on the virulence of were analyzed by transmission and confocal electron microscopy, reactive oxygen species (ROS) production, and apoptosis, detected by flow cytometry with dichlorofluorescein 2',7'-diacetate and annexin-V binding, respectively, and confirmed by TUNEL. The interaction of and with actin was analyzed by docking, and the amoebicidal activity was established with the model; amebic liver abscess (ALA) development was evaluated by magnetic resonance (MR) and validated .

Effect of Gallic acid and Myricetin on ovarian cancer models: a possible alternative antitumoral treatment.

Background: Ovarian cancer is the leading cause of mortality among malignant gynecological tumors. Surgical resection and chemotherapy with intravenous platinum/taxanes drugs are the treatments of choice, with little effectiveness in later stages and severe toxicological effects. Therefore, this study aimed to evaluate the antineoplastic activity of gallic acid (GA) and myricetin (Myr) administrated peritumorally in Nu/Nu mice xenotransplanted with SKOV-3 cells.

Biological and toxicological evaluation of Rhus trilobata Nutt. (Anacardiaceae) used traditionally in mexico against cancer.

Background: Rhus trilobata Nutt. (Anacardiaceae) (RHTR) is a plant of Mexico that is traditionally used as an alternative treatment for several types of cancer. However, the phytochemical composition and potential toxicity of this plant have not been evaluated to support its therapeutic use.