Publications by authors named "Lorenzo Defidio"

Background: Robotic-assisted surgery (particularly with the da Vinci Surgical System) has revolutionized urological interventions. The advent of the Versius Surgical System introduces a compelling alternative. This study compares outcomes of extraperitoneal robot-assisted radical prostatectomy (eRARP) using da Vinci and Versius, presenting the largest case series to date.

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Introduction: This study aimed to evaluate the effect of coronavirus disease (COVID-19) on the patients' referral in the pregnant population and also investigate each treatment approach's advantages and disadvantages for acute renal colic in pregnancy.

Methods: In this retrospective study, we included all pregnant women with ureteral stones referred to a referral center between January 2019 and March 2021.

Results: Among 53 pregnant women, 18 (33.

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Background: Myelolipoma is a benign neoplasm of the adrenal cortex, composed of fat and hematopoietic cells. Although myelolipoma is benign, differentiation from adrenocortical cancer may be difficult. The presence of adrenal and extra-adrenal myelolipomas simultaneously is sporadic, making it a challenging case, especially when the preoperative diagnosis is ambiguous.

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Different strategies have been proposed to treat cytokine storm syndrome (CSS), the final deadly complication of COVID-19. One approach is to target CSS by blocking the interleukin-6 (IL-6) pathway. A promising group of medications blocking the IL-6 pathway is α-blockers, such as prazosin.

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Objectives: We aimed to evaluate the prevalence and predictive factors of postoperative infections after a standardized low-pressure RIRS technique. The secondary outcome was comparing surgeons' experience in terms of infective complication and stone-free rate.

Methods: A single-center retrospective analysis was conducted on all patients who underwent RIRS for kidney stones between January 2018 and February 2019.

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Transurethral resection of bladder tumor (TURBT) is still the gold standard for the diagnosis, treatment, and staging of nonmuscle invasive bladder cancer. En bloc resection of bladder tumor (EBRT) has been recently introduced to overcome the limitations of conventional TURBT. EBRT potential advantages are (1) complete resection, (2) a more precise and controlled resection (potentially fewer complications), (3) better sample orientation for histopathology analysis, (4) presence of detrusor in the specimen, and (5) less tumor seeding on normal urothelium by tumor fragments.

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This exploratory retrospective analysis examined any potential prognostic role of preoperative neutrophil lymphocyte ratio (NLR) for progression-free survival (PFS) and time to endoscopically verified upper tract or bladder recurrence-free survival (RFS) in upper tract urothelial cancer (UTUC) patients selected for endoscopic treatment with subsequent endosurveillance. Eligibility criteria were natural orifice endoscopically retrogradely treated low-risk and imperative UTUC patients treated between 2005 and 2019, with biopsy confirmed diagnosis and 12 months minimum follow-up. For PFS, optimal NLR cutoff value was derived by log-rank test.

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To evaluate ablative safety and efficacy of thulium-holmium:YAG (TL-HL:YAG) duo laser in renal conserving retrograde intrarenal surgery (RC-RIRS) in upper tract urothelial carcinoma (UTUC). A retrospective study was performed on 178 consecutive patients referred for consideration of RC-RIRS UTUC-eLA (endoscopic laser ablation) in a tertiary center (January 2005 to December 2018). Key data were recorded using a standardized study proforma.

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Introduction: To report the long-term multicenter experience with retrograde intrarenal holmium-laser incision (RIR-HoLI) in the management of symptomatic renal sinus cysts (RSCs). In the literature, RIR-HoLI has been shown to be a safe and effective treatment, but there are only a few reports regarding long-term results and reproducibility of this procedure.

Material And Methods: From June 2010 to June 2015, 14 patients with symptomatic RSCs underwent RIR-HoLI.

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Objective: To evaluate ureteral compliance through semirigid ureteroscopy (sURS) in order to select the proper ureteral access sheath (UAS) size for retrograde intrarenal surgery (RIRS).

Patients And Methods: In a prospective study, 100 consecutive patients selected for elective sURS or RIRS were recruited. Each patient, initially underwent 9.

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Background And Purpose: Controversy exists in the literature regarding flexible ureterorenoscopy (F-URS) durability, with a variable expected number of uses from a new F-URS. In this study, a tertiary center experience with the use of two consecutive F-URS is reported and suggestions as to how to improve durability further are made.

Materials And Methods: All F-URS performed in the same tertiary care center between July 2009 and February 2011, with two new instruments Flex-X, were reviewed retrospectively.

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Article Synopsis
  • The study examines the effectiveness of Thulium laser ablation (TLA) compared to Holmium:YAG laser ablation in treating upper urinary tract transitional cell carcinomas (UUT-TCC) during retrograde intra-renal surgery (RIRS).
  • It involved a cohort of 59 patients whose surgery outcomes were evaluated by four blinded surgeons using a Likert scoring system to measure various performance aspects of both laser types.
  • Results showed that TLA provided similar recurrence-free survival rates while offering better scores in factors like stability, precision, reduced bleeding, and lower rates of mucosal perforation, especially for tumors smaller than 1.5 cm, although challenges remained for larger tumors.
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Endoscopic evaluation and management of different pathological conditions involving the upper urinary tract using rigid or flexible endoscopes, is now readily feasible and has been shown to be safe and efficacious even in the smallest children. Paediatric ureteroscopic procedures are similar to their adult counterparts, so that basic endoscopic principles should be observed. Aims of the management should be complete clearance of stones, preservation of renal function and prevention of stone recurrence.

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We report a case of a right upper urinary tract tumor (UUTT) in a patient submitted two years before to a radical cystectomy with an orthotopic urinary diversion. Excretory urography (IVP) showed a filling defect in the right renal pelvis, confirmed by contrast enhanced multislice spiral computerized tomography and virtual ureteroscopy. A flexible uretero-renoscopy showed a papillary tumor in the renal pelvis.

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This article describe a new technique for treating post-prostatectomy urinary incontinence. We performed this procedure on 15 patients with a follow-up of 2 to 9 months. All of the patients had radical retropubic prostatectomies and a urodynamically confirmed stress urinary incontinence for more than one year; 3 of the 15 (20%) had detrusor instability.

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Objective: The aim of our work was to show that, in addition to the standard technique, double-J ureteral stent can be positioned also through a prevalently fluoroscopic method, that uses a guide wire inside the ureter and a radiopaque pusher with a metal tip.

Methods: The access can be anterograde or retrograde. In both cases, after the guide wire is in the ureter, we remove the cystoscope or the nephrostomy tube, advance the stent over the guide wire with the metal tip pusher, which can be easily localized through the amplifier.

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Preview The complex pathways of testicular pain and referred pain are becoming better understood. Still, the precise physical source can be elusive, and advances in medical knowledge mean nothing to the patient if his pain cannot be relieved. Most patients can be examined and treated in the primary care office with readily available techniques.

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