Innovative strategies for post-stroke depression: integrating traditional Chinese medicine with neurobiological insights, including the gut-brain axis.

Post-stroke depression (PSD) is a debilitating condition affecting more than one-third of stroke survivors, leading to significant impairments in mood, cognitive function, and overall quality of life. While conventional treatments like selective serotonin reuptake inhibitors (SSRIs) are commonly used, their efficacy is often limited, and they are associated with adverse side effects. Emerging research underscores the critical roles of neuroinflammation, neurotransmitter imbalances, and disruptions in the gut-brain axis in the development and progression of PSD, suggesting that targeting these pathways could lead to more effective therapeutic outcomes.

Coordination-Controlled Synthesis of Aluminum Nanoparticles: Insights from AlH·(NMP) Complexes.

The controlled chemical synthesis of aluminum nanocrystals (Al NCs) is crucial for their applications in plasmonics, photocatalysis, and optoelectronics. However, there is still a lack of correlation between the precursor of Al hydride N-methylpyrrolidine (AlH·(NMP)) and the Al NC synthesis outcomes. Here, we report the synthesis of AlH·(NMP) complexes with different coordination numbers (x from 1.

A new health literacy scale for staff in preschool childcare institution: development and preliminary validation.

Background: The health literacy of staff in preschool childcare institution is an important issue to consider in providing healthcare for children aged 3-6 years, which could contribute to reducing incidence of diseases and accidental injuries as well as maintaining children's good health. Seldom instruments have been designed to measure health literacy across this group. This research aims to develop a health literacy scale for staff in preschool childcare institutions and validate its psychometric properties.