The clinical features, muscle pathology, and role of autophagy in anti-Ku-positive patients.

Aims: This study aimed to examine the clinical and muscle histological characteristics of anti-Ku-positive patients. A preliminary investigation into the involvement of autophagy was conducted as well.

Methods: Clinical characteristics, laboratory findings, and muscle histological features were collected from patients with isolated anti-Ku antibodies at the Department of Neurology, First Medical Center of the PLA General Hospital, between February 2011 to June 2024.

Evaluation of the effectiveness of using prednisolone, tacrolimus, and intravenous immunoglobulin combination therapy on immune-mediated necrotizing myopathy-A non-randomized, observational research.

Objective: To recruit immune-mediated necrotizing myopathy (IMNM) patients with extramuscular manifestations who were refractory to initial therapy with either monotherapy with prednisolone or dual therapy with prednisolone and immunosuppressants. These patients subsequently received a combination of prednisolone, tacrolimus, and intravenous immunoglobulin (IVIG), and the efficacy of this treatment regimen was assessed in patients with IMNM.

Method: ①Clinical data and treatment measures are as follows: This study enrolled IMNM patients who were treated at the Neurology Department of the First Medical Center of PLA General Hospital from April 2020 to May 2023.

Corrigendum: Characteristics of cardiac involvement in immune-mediated necrotizing myopathy.

[This corrects the article DOI: 10.3389/fimmu.2023.

Characteristics of cardiac involvement in immune-mediated necrotizing myopathy.

Objective: To investigate the characteristics of cardiac involvement due to Immune-mediated Necrotizing Myopathy (IMNM).

Methods: Patients diagnosed with Immune-mediated Necrotizing Myopathy (IMNM) who attended the Department of Neurology and the Department of Rheumatology and Immunology at the First Medical Center of the PLA General Hospital between February 2011 and June 2022 were collected. Clinicopathological diagnosis of IMNM was performed according to the criteria established by the European Neuromuscular Center (ENMC).

Muscular pathological features in patients with myasthenia gravis.

Objective: To analyze muscle histopathology of myasthenia gravis (MG) patients and further explore the underlying mechanism comparing with previous literature.

Materials And Methods: We analyzed the clinicopathological features of 8 MG patients who had muscle biopsy examinations.

Results: Eight patients with a diagnosis of MG were retrospectively recruited from the Chinese PLA General Hospital.

Clinical efficacy and safety of statin treatment after carotid artery stenting.

The randomized controlled trail was carried out to investigate the influence of statin pre-treatment on clinical efficacy of carotid artery stenting (CAS). 160 eligible patients were randomly divided into statin group ( = 82) and control group ( = 78). The patients in statin group received 40 mg atorvastatin daily 7 days before operation.