[Holmium laser ω-shaped pre-transection of prostate apex with preservation of the bladder neck improves urinary continence and sexual function in BPH patients after HoLEP].

Objective: To investigate the effect of holmium laser ω-shaped pre-transection of the prostate apex (PTPA) with preservation of the bladder neck on the urinary continence and sexual function of the patients with BPH after transurethral holmium laser enucleation of the prostate (HoLEP).

Methods: This retrospective study included 165 cases of BPH undergoing holmium laser ω-shaped PTPA with preservation of the bladder neck following HoLEP from January 2018 to January 2023. We recorded and compared the baseline, perioperative and 12-month follow-up data on the patients, and evaluated their urination function using IPSS, maximum urinary flow rate (Qmax), postvoid residual urine volume (PVR), and quality of life (QOL) scores.

Subcycle spectral structures of light-induced states in attosecond transient absorption of helium dressed by an orthogonally polarized laser field.

We present the subcycle spectral structures from attosecond transient absorption spectra of helium by accurately solving the full three-dimensional time-dependent Schrödinger equation in extreme ultraviolet attosecond pulse and an orthogonally polarized infrared (IR) laser field. We discover that the subcycle spectral features associated with the dressed 1 ( ≥ 4) states and light-induced states, referred to as , , and , can be strongly modified or even enhanced when the strength ratio of the orthogonal laser field in two polarized laser directions changes. To understand the spectral evolution of the subcycle structures, we perform calculations of the time-dependent population and time-frequency analysis.

Synthesis of the Cu-Doped Dual-Emission Fluorescent Carbon Dots and Its Analytical Application.

New Cu-doped dual-emission carbon dots (D-CDs) were synthesized rapidly and simply via a one-pot solvothermal method, and its special photoluminescence mechanism was studied. D-CDs have two fluorescence (FL) emission peaks under one-wavelength excitation and can be used as dual-signal sensor which is usually designed with two or more substances. The prepared CDs show excellent water solubility, photostability, salt tolerance, oxidation resistance, and special optical properties.

Blockade of MMP-2 and MMP-9 inhibits corneal lymphangiogenesis.

Purpose: To investigate the roles of a selective MMP-2 and -9 inhibitor (SB-3CT) in corneal inflammatory lymphangiogenesis.

Methods: The expression of MMP-2 and -9 in the cornea after suture inplacement, treated with SB-3CT or negative control, was detected by real-time polymerase chain reaction (PCR). Inflammatory corneal neovascularization (NV) was induced by corneal suture placement.

Tea Polysaccharides and Their Bioactivities.

Tea () is a beverage beneficial to health and is also a source for extracting bioactive components such as theanine, tea polyphenols (TPP) and tea polysaccharides (TPS). TPS is a group of heteropolysaccharides bound with proteins. There is evidence showing that TPS not only improves immunity but also has various bioactivities, such as antioxidant, antitumor, antihyperglycemia, and anti-inflammation.

CXCL12/CXCR4 axis regulates neovascularization and lymphangiogenesis in sutured corneas in mice.

The present study aimed to determine the plausible functional role of chemokine (C‑X‑C motif) ligand 12 (CXCL12/chemokine (C‑X‑C motif) receptor 4 (CXCR4) in inflammatory corneal hemangiogenesis and lymphangiogenesis in vivo. Corneal hemangiogenesis and lymphangiogenesis were induced by placing an 11‑0 nylon suture in an intrastromal position. The expression levels of the vascular endothelial growth factor (VEGF) family, CXCL12 and CXCR4 in the corneas were investigated in the corneas using reverse transcription‑quantitative polymerase chain reaction and immunohistochemistry.

[Measurement of Trace C2H6 Based on Optical-Feedback Cavity-Enhanced Absorption Spectroscopy].

Ethane is one of major fault characteristic gases dissolved in power transformer, the detection of Ethane with high accuracy and sensitivity is the key of dissolved gas analysis. In this paper, based on optical feedback theory and cavity-enhanced absorption spectroscopy, combined with quantum cascade laser, a detection system for dissolved gas C2 H6 in transformer oil was built up. Based on the symmetry of the individual cavity modes, the phase matching of returning light in resonance with the cavity was achieved through LabVIEW codes.

[Parallel PLS algorithm using MapReduce and its aplication in spectral modeling].

Partial least squares (PLS) has been widely used in spectral analysis and modeling, and it is computation-intensive and time-demanding when dealing with massive data To solve this problem effectively, a novel parallel PLS using MapReduce is proposed, which consists of two procedures, the parallelization of data standardizing and the parallelization of principal component computing. Using NIR spectral modeling as an example, experiments were conducted on a Hadoop cluster, which is a collection of ordinary computers. The experimental results demonstrate that the parallel PLS algorithm proposed can handle massive spectra, can significantly cut down the modeling time, and gains a basically linear speedup, and can be easily scaled up.

Blocking neuropilin-2 enhances corneal allograft survival by selectively inhibiting lymphangiogenesis on vascularized beds.

Purpose: To investigate the potential inhibitory effects of RNA interference-mediated knockdown of neuropilin-2 (NP2) on inflammation-induced corneal hemangiogenesis and lymphangiogenesis, and whether selective inhibition of lymphangiogenesis on vascularized recipient beds before transplantation improves the graft survival.

Methods: Mouse lymphatic endothelial cells were transfected with the plasmid expressing artificial microRNA (amiRNA) against mouse NP2, and the down-regulation of VEGF-C-induced NP2 expression by NP2 amiRNA was evaluated by real-time PCR and western blot assays. Next, NP2 amiRNA or negative control amiRNA was injected intrastromally into BALB/c mouse model of suture-induced corneal neovascularization three days after surgery.

[Randomized control study of sequential non-invasive following short-term invasive mechanical ventilation in the treatment of acute respiratory distress syndrome as a result of existing pulmonary diseases in elderly patients].

Objective: To evaluate the feasibility and the efficacy of sequential non-invasive mechanical ventilation (MV) following short-term invasive MV in the treatment of acute respiratory distress syndrome (ARDS) consequent to pulmonary diseases in the elderly patients.

Methods: Thirty-two elderly patients of ARDS were enrolled and grouped into two groups (sequential therapy group and control group) randomly (16 cases in each group). Both groups with tracheal intubation received the following ventilation modality in the first 24 hours: control/assistant-control+positive end expiratory pressure (PEEP)+sustained inflation (SI), and when the patients' conditions were relieved, the ventilation modality was switched to synchronized intermittent mandatory ventilation (SIMV)+pressure support ventilation (PSV)+PEEP.

Identification of a new functional domain in angiopoietin-like 3 (ANGPTL3) and angiopoietin-like 4 (ANGPTL4) involved in binding and inhibition of lipoprotein lipase (LPL).

Angiopoietin-like 3 (ANGPTL3) and angiopoietin-like 4 (ANGPTL4) are secreted proteins that regulate triglyceride (TG) metabolism in part by inhibiting lipoprotein lipase (LPL). Recently, we showed that treatment of wild-type mice with monoclonal antibody (mAb) 14D12, specific for ANGPTL4, recapitulated the Angptl4 knock-out (-/-) mouse phenotype of reduced serum TG levels. In the present study, we mapped the region of mouse ANGPTL4 recognized by mAb 14D12 to amino acids Gln(29)-His(53), which we designate as specific epitope 1 (SE1).