Comparative Transcriptomic Analysis of the Liver and Spleen in Ussuri Catfish () Challenged with Polyriboinosinic Polyribocytidylic Acid (Poly(I:C)).

Poly (I:C), a viral mimic, is capable of activating the antiviral immune mechanisms in teleosts. In this study, we investigated the transcriptional responses of Ussuri Catfish () to poly (I:C) stimulation at 3 and 48 h, focusing on the similarities and differences in antiviral mechanisms exhibited in the liver and spleen. At 3 h, the signaling pathways that were concurrently enriched in both the spleen and liver include JAK-STAT, TNF, NF-κB, RIG-I-like receptor, and NOD-like receptor.

Comprehensive multi-omics and biochemical analysis to elucidate the molecular response mechanisms of gill and kidney tissues under acute salinity stress in Pseudobagras ussuriensis.

Unlabelled: Acute salinity stress critically impacts aquaculture efficiency by inducing physiological disruptions in fish. This study investigated the molecular adaptation mechanisms of exposed to 10 ppt NaCl for 96 h, integrating transcriptomic and metabolomic analyses of gill and kidney tissues. In transcriptomics, 2,554 and 1,066 differentially expressed genes (DEGs) were identified in gills and kidneys, respectively, with significant enrichment in pathways related to energy metabolism (glycolysis, oxidative phosphorylation), membrane dynamics (glycerophospholipid metabolism), and immune-osmoregulatory crosstalk (HIF-1, TNF, and Jak-STAT signaling).

Integrated analysis of biochemical, transcriptomic, and metabolomic response mechanisms in Ussuri catfish (Pseudobagrus ussuriensis) under acute heat stress.

Fish metabolism, growth, development, and physiological conditions are highly sensitive to fluctuations in water temperature. The Ussuri catfish (Pseudobagrus ussuriensis) is an important native economic species in China. However, research on heat stress in P.

siRNA silencing and hypoxia challenge indicate that the function of common carp (Cyprinus carpio) hif-1αb genes are tightly linked to hif-1αa and hif-3α genes.

Background: Fishes are susceptible to hypoxia stress, while the common carp is known for its high tolerance to hypoxia. The hypoxia-inducible factor (HIF) pathway directly regulates the cell's response to hypoxia. Still, it is currently unknown which members of the hif-α genes are present in common carp and their specific functions.

Transcriptome Analysis of Brain and Skin Reveals Immune Responses to Acute Hypoxia and Reoxygenation in .

is an unscaled fish that is more susceptible to skin damage than scaled fish. To investigate the impacts of hypoxia and reoxygenation on skin and brain immunity, juvenile were subjected to hypoxia conditions (DO: 0.8 ± 0.