Publications by authors named "Lei-Xin Zhuang"

Three undescribed isosteroidal alkaloids (1-3), along with two known ones (4, 5) were isolated from the bulbs of Fritillaria ussuriensis Maxim, their structures were established by comprehensive analyses of the 1D, 2D-NMR and HR-ESI-MS data. Meanwhile, LPS-activated RAW 264.7 macrophages were used to determine the potential anti-inflammatory activity of all the alkaloids in vitro.

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Four new sesquiterpenoids named atrchiterpenes A-D (1-4), a new natural product (5), and twelve known compounds (6-17) were isolated from Atractylodes chinensis (DC.) Koidz. Compound 1 was a rare N-containing eudesmane-type sesquiterpenoid.

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Article Synopsis
  • Plants in the Schisandraceae family have historically been used in folk medicine to treat various ailments such as coughs, asthma, and sleep issues.
  • The review focuses on summarizing the phytochemistry, pharmacology, and synthesis of triterpenoids from this plant family, using literature from 2014 to 2021.
  • From the research, 211 new triterpenoids were identified, showcasing diverse structures with significant pharmacological properties, including anti-viral and anti-tumor effects, alongside successful synthesis of several compounds.
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