Background: While the hippocampus is not part of the nigrostriatal dopaminergic pathway, influence of Parkinson's disease (PD) on the hippocampus has been consistently implicated. However, it is not clear how the hippocampal changes contribute to the pathology of PD.
Objectives: We aimed to elucidate the physiological changes of the hippocampus in its orchestration with the rest of the brain.