Hepatocellular carcinoma is the most prevalent form of primary liver cancer, commonly associated with chronic liver conditions like hepatitis and alcohol abuse. Primary hepatic lymphoma (PHL), a rare type of non-Hodgkin lymphoma originating in the liver, primarily affects men around the age of 50. Chronic hepatitis B and C are also recognized as risk factors for PHL.
View Article and Find Full Text PDFPrimary pericardial synovial sarcoma (PPSS) is a rare and aggressive cancer that arises from pluripotent mesenchymal cells of the pericardium. The pathognomonic genetic hallmark is the chromosomal translocation t(X;18)(p11;q11), resulting in the SS18-SSX fusion oncogene, which, down the line, disrupts transcription regulation and chromatin remodeling, ultimately leading to carcinogenesis. In our article, we describe two cases of PPSS in previously healthy young men, managed with multidisciplinary teams, along with a review of the literature of cases reported to date.
View Article and Find Full Text PDFUrinary tract leiomyomas are rare, benign mesenchymal tumors that are traditionally treated with complete surgical excision. We present three cases of urinary tract leiomyoma - two located in the bladder and one in the ureter. Both bladder leiomyomas were treated with transurethral resection of bladder tumor (TURBT) with no evidence of recurrent disease, while the upper tract leiomyoma was managed with surveillance by patient preference, which to our knowledge, has not been previously described.
View Article and Find Full Text PDFHepatocellular carcinoma (HCC) arises from several different etiologies and carries a poor prognosis. Extrahepatic metastases of HCC are most frequently found in the lungs, lymph nodes, and bones, with adrenal metastases reported in less than 15% of metastatic cases. Herein, we report a case of a 71-year-old man without prior liver disease who presented with a 9-cm right adrenal mass extending into the IVC consistent with HCC on subsequent surgical pathology and immunohistochemical staining.
View Article and Find Full Text PDFis a slow-growing atypical mycobacterium. It is a photochromogen; when exposed to light, it produces yellow pigment. In humans, it manifests as a localized granuloma or sporotrichotic lymphangitis.
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