Dujieqing decoction suppresses multiple myeloma growth by inhibiting the Wnt/β-catenin pathway.

Objective: To explore the therapeutic potential of the Dujieqing (DJQ) decoction for multiple myeloma (MM) and elucidate its mechanism of action.

Methods: RPMI8226 cells were treated with DJQ-containing serum (DJQ-CS) and a Wnt/β-catenin pathway inhibitor, XAV-939. Cell counting kit-8 assay was used to examine cell viability, and flow cytometry was performed to examine apoptosis.

The advantage of polyethylene glycol electrolyte solution combined with lactulose in patients with long interval preparation-to-colonoscopy.

Background/aims: The main aim of the present study was to assess the efficacy of polyethylene glycol electrolyte (PEG) solution combined with lactulose in bowel preparation to find a new method for colonoscopy preparation to improve the quality of colonoscopy in patients with long interval preparation-to-colonoscopy (P-C).

Materials And Methods: A prospective, randomized, endoscopist-blinded and placebo-controlled study was conducted. Three hundred sixty patients who were scheduled for colonoscopy were enrolled in the study.

Heavy metal pollution in surface soils of Pearl River Delta, China.

Heavy metal pollution is an increasing environmental problem in Chinese regions undergoing rapid economic and industrial development, such as the Pearl River Delta (PRD), southern China. We determined heavy metal concentrations in surface soils from the PRD. The soils were polluted with heavy metals, as defined by the Chinese soil quality standard grade II criteria.