Epstein-Barr Virus Corneal Endotheliitis and Uveitis in a Patient With Extranodal Natural Killer/T-Cell Lymphoma.

Purpose: To report a case of Epstein-Barr virus (EBV) corneal endotheliitis and uveitis in a patient diagnosed with extranodal natural killer/T-cell lymphoma (ENKTL).

Methods: This is a case report performed at a tertiary care center in the Republic of Korea.

Results: A 64-year-old man presented with decreased vision in his right eye that had persisted for 4 days.

Effects of matrix metalloproteinase inhibition in cultured human Tenon's capsule fibroblasts.

Background: This study aimed to compare the characteristics of anterior and posterior human Tenon's capsule fibroblasts and determine the effect of matrix metalloproteinase (MMP) inhibition on cultured human Tenon's capsule fibroblasts.

Methods: Tissues obtained from the anterior and posterior Tenon's capsules were partially incised, cultured, and subjected to microarray analysis. Electrophoresis was performed on the cells treated with Ilomastat (MMP-9 inhibitor), and collagen 1, 3, and 6.

Repeatability of Corneal Epithelial Thickness Map Using Anterior-Segment Optical Coherence Tomography in Normal and Corneal Disease Patients.

Purpose: To evaluate the repeatability of corneal epithelial thickness (CET) measurements in normal eyes and eyes diagnosed with corneal disease using the epithelial thickness map (ETM) of anterior-segment optical coherence tomography (OCT).

Methods: In this retrospective study, patients with three OCT scans using the ETM mode of Cirrus OCT between October 2021 and January 2024 were reviewed. Two groups of subjects were included: (1) normal subjects with no history of ophthalmic surgery, corneal diseases, and topical antiglaucoma medication uses; and (2) subjects with corneal diseases including dry eye syndrome, recurrent corneal erosion, pterygium, and others.

The Proportion of Ocular Involvement and Characteristics of Dry Eye Parameters in Primary Sjögren Syndrome Referred from the Rheumatology Department.

Purpose: To report the proportion of ocular involvement in primary Sjögren syndrome (pSS) and to analyze various dry eye indexes and serum titers of markers depending on whether ocular involvement has occurred or not.

Methods: This retrospective study considered 214 patients referred from the rheumatology department for pSS workup. Symptom questionnaires, ocular surface stain score (OSS), Schirmer test, tear breakup time (TBUT), meibomian gland dropout, meibum quality, meibum expressibility, lid margin abnormalities, and lipid layer thickness were evaluated.

Comparison of intraocular lens power calculation formulas in patients with a history of acute primary angle-closure attack.

Background: To compare the accuracy of nine intraocular lens (IOL) power calculation formulas, including three traditional formulas (SRK/T, Haigis, and Hoffer Q) and six new-generation formulas (Barrett Universal II [BUII], Hill-Radial Basis Function [RBF] 3.0, Kane, Emmetropia verifying optical [EVO], Ladas Super, and Pearl-DGS) in patients who underwent cataract surgery after acute primary angle closure (APAC).

Methods: In this retrospective cross-sectional study, 44 eyes of 44 patients (APAC) and 60 eyes of 60 patients (control) were included.

Repeatability and Agreement of Chord Mu between Scheimpflug Tomography and Swept-Source Optical Coherence Tomography.

Purpose: To evaluate repeatability and agreement of chord mu between Scheimpflug tomography (Pentacam HR) and sweptsource optical coherence tomography-based optical biometer (IOLMaster 700).

Methods: In this retrospective study, 63 eyes from 33 patients were included. Chord mu, X and Y Cartesian distances between the corneal vertex and the pupil center (Px and Py), and the pupil diameter were compared using two instruments.

Toxicity of simultaneous intrastromal and intracameral injection of voriconazole on corneal endothelium in a rabbit model.

Purpose: To investigate the toxicity of repeated simultaneous intrastromal and intracameral injections of voriconazole in corneal endothelial cells in a rabbit model.

Methods: Thirty-six eyes of 18 New Zealand white rabbits (six eyes per group) were divided into 6 groups according to the concentration of voriconazole (Group A, 0%; Group B, 0.05%; Group C, 0.

Ocular Surface and Tear Cytokine Changes after Cataract Surgery in Patients with Type 2 Diabetes.

Purpose: To evaluate changes in ocular surface indices and tear cytokines after cataract surgery in type 2 diabetic patients.

Methods: Ocular surface indices and concentrations of tear cytokines (MCP-1, IL-6, IL-8, and VEGF) were evaluated at baseline and one week and one month postoperatively.

Results: Patients (30 diabetic and 30 control) were enrolled.

Agreement between Two Swept-Source Optical Coherence Tomography Biometers and a Partial Coherence Interferometer.

Purpose: To evaluate the level of agreement between ANTERION (Heidelberg Engineering, Heidelberg, Germany), OA-2000 (Tomey, Nagoya, Japan), and IOLMaster 500 (Carl Zeiss AG, Jena, Germany).

Methods: Fifty-one eyes of 51 patients were included in the study. Flat keratometry (K) and steep K, vector component of astigmatism (Jackson cross-cylinder at 0° and 90° [J0] and Jackson cross-cylinder at 45° and 135° [J45]), anterior chamber depth, and axial length were compared using the three devices.

Agreement between Scheimpflug Camera and the Swept-source Optical Coherence Tomography Measurements in Keratometry and Higher-order Aberrations.

Purpose: To evaluate the compatibility of corneal curvature and astigmatism, and higher-order aberrations (HOAs) measured by the Scheimpflug camera Pentacam HR and the swept-source optical coherence tomography ANTERION.

Methods: This prospective study included normal subjects with no ophthalmic history. Steep keratometry (K), flat K, astigmatism and its axis of the anterior and posterior surfaces, total corneal power, and HOAs using the two instruments were compared.

Clinical Manifestation and Risk Factors Associated With Remission in Patients With Filamentary Keratitis.

Purpose: This study investigated the clinical manifestation and risk factors associated with remission in filamentary keratitis.

Design: Retrospective, interventional, comparative case series.

Methods: We retrospectively reviewed the medical records of 116 patients with filamentary keratitis diagnosed and treated between January 2012 and December 2018.

Therapeutic effects of three human-derived materials in a mouse corneal alkali burn model.

To compare the therapeutic effects of human derivatives in a mouse alkali burn model. The right eyes of mice were injured using NaOH. After alkali injury, one of the following agents was topically administered for 7 d: human amniotic membrane (hAM) suspension, human umbilical cord serum (hUCS), and human peripheral blood serum (hPBS), or saline.

Medical Litigations Associated with Cataract Surgery in Korea.

Background: To analyze the results of court rulings about medical litigations related to cataract surgery in Korea.

Methods: We collected 50 anonymized judgements regarding cataract surgery between 2000 and 2016 and analyzed the reasons for the medical litigations, the court rulings, the reasons for compensation, and the amount claimed and finally awarded.

Results: Forty-eight litigations (96%) resulted from errors in treatment, and the reasons were as follows: endophthalmitis, dissatisfaction of visual outcome or ocular discomfort, bullous keratopathy or corneal opacity, retinal detachment, glaucoma or vitreous hemorrhage due to the progression of an underlying diabetic retinopathy, and others in order.

Prevalence and risk factors of strabismus in children and adolescents in South Korea: Korea National Health and Nutrition Examination Survey, 2008-2011.

Purpose: To evaluate the prevalence and risk factors associated with horizontal strabismus in children and adolescents in South Korea.

Methods: A total of 5,935 children and adolescents 5-18 years of age who participated in the fourth and fifth Korean National Health and Nutrition Examination Survey (KNHANES IV-V) from July 2008 to December 2011 were evaluated and the prevalence of horizontal strabismus was estimated. Univariate and multivariate logistic regression analyses were conducted to determine the association between demographic, socioeconomic and clinical risk factors and clinically significant exodeviation (≥15 prism diopters [PD]) and esodeviation (≥10 PD).

Conjunctival Flap with Biodegradable Collagen Matrix Implantation for the Treatment of Scleromalacia after Periocular Surgery.

: To report a new surgical procedure using biodegradable collagen matrix (Ologen) implantation with conjunctival flap for reconstruction of scleromalacia after periocular surgery. : A total of 26 areas of 25 eyes in 25 patients were included. We divided all eyes according to the preoperative extent of calcified plaque or scleral defect as follows: small, large, and large and severe.

A modified-simple technique of removing the lens cortex during cataract surgery.

We describe here a surgical technique of removing the remaining cortex after phacoemulsification without performing the conventional irrigation/aspiration (I/A) procedure. In this technique, the remaining cortex attached to the posterior capsule was separated and dissected into several pieces by continuous irrigation with balanced salt solution, which was supplied through a syringe attached to a bent, blunt-tip needle. Approximately, 10 s of manual irrigation separated most of the remaining cortex from the posterior capsule.

Safety of Using Matrix Metalloproteinase Inhibitor in Experimental Glaucoma Filtration Surgery.

We evaluated the safety of matrix metalloproteinase (MMP) inhibitor in experimental glaucoma filtration surgery in an animal model. Fifteen New Zealand white rabbits underwent an experimental trabeculectomy and were randomly allocated into 3 groups according to the adjuvant agent: no treatment group (n = 5), 0.02% mitomycin C (MMC) soaking group (n = 5), and MMP inhibitor (ilomastat) subconjunctival injection group (n = 5).

Restoration of Complicated Epicanthus: Modified Reverse Skin Redraping With Mini-epicanthoplasty for Rescue in Unsatisfied Epicanthoplasty Patients.

Purpose: We had reported the surgical outcome of reverse skin redraping technique for restoration of previously performed epicanthoplasty. In this study, we introduce a modified reverse skin redraping technique that added mini-epicanthoplasty in patients with unsatisfactory results after epicanthoplasty.

Methods: Three hundred twenty-four patients (288 female and 36 male patients) who had unsatisfied results with previous epicanthoplasty and that were treated with our modified restoration surgery were included in this study.

Comparison of Two Optical Biometers.

Purpose: To compare a new optical biometer device, Galilei G6 (Ziemer, Port, Switzerland), with the present optical biometer, Lenstar LS 900 (Haag-Streit, Koeniz, Switzerland), for intraocular lens (IOL) power calculation.

Methods: One hundred forty eyes of 140 cataract patients were evaluated with two optical biometers: the Galilei G6 and the Lenstar. The mean keratometry (K), axial length (AL), anterior chamber depth (ACD), crystalline lens thickness (LT), white-to-white (WTW), and IOL powers using the SRK/T, Holladay 1, Hoffer Q, and Haigis formulas were compared.

Pathogenesis and treatments of TGFBI corneal dystrophies.

Transforming growth factor beta-induced (TGFBI) corneal dystrophies are a group of inherited progressive corneal diseases. Accumulation of transforming growth factor beta-induced protein (TGFBIp) is involved in the pathogenesis of TGFBI corneal dystrophies; however, the exact molecular mechanisms are not fully elucidated. In this review article, we summarize the current knowledge of TGFBI corneal dystrophies including clinical manifestations, epidemiology, most common and recently reported associated mutations for each disease, and treatment modalities.

Evaluation of dry eye and meibomian gland dysfunction after cataract surgery.

Purpose: To evaluate dry eye and meibomian gland dysfunction after cataract surgery.

Design: Prospective observational case series.

Methods: We studied 58 eyes of 48 patients who underwent phacoemulsification and evaluated them preoperatively and at 1 month and 3 months postoperatively.

Epithelial wound healing after cataract surgery comparing two different topical fluoroquinolones.

Purpose: To compare the epithelial wound healing response of two preservative-free fluoroquinolones, moxifloxacin and levofloxacin, in patients who underwent cataract surgery.

Materials And Methods: In this prospective, evaluator-masked, randomized clinical trial, 59 eyes of 50 patients who underwent cataract surgery were enrolled. Patients were randomized to receive moxifloxacin 0.

Comparison of intraocular pressures after myopic laser-assisted subepithelial keratectomy: tonometry-pachymetry, Goldmann applanation tonometry, dynamic contour tonometry, and noncontact tonometry.

Purpose: To compare intraocular pressure (IOP) measurements using a new tonometer-pachymeter device (Tonopachy), Goldmann applanation tonometry (GAT), dynamic contour tonometry (DCT), and noncontact tonometry (NCT) before and after myopic laser-assisted subepithelial keratectomy (LASEK).

Setting: Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, South Korea.

Design: Prospective comparative observational study.