Publications by authors named "Kun-Long Yan"

Article Synopsis
  • Human caliciviruses, especially norovirus genotype GII.4, are significant causes of viral diarrhea in children, as highlighted by a study in China.
  • Among 295 children with acute diarrhea, 10.85% tested positive for HuCV, with most being HBGA secretors or partial secretors, while only a small percentage of asymptomatic children tested positive.
  • The findings suggest that blood type O may be linked to a higher risk of GII.3 infection, but due to the small sample size, additional research is needed for confirmation.
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Article Synopsis
  • Human adenovirus (HAdV) significantly contributes to respiratory infections in children under 14 years, particularly in Lanzhou City, China, with a low overall detection rate of 6.33%.
  • The most common strain identified was AdV3, while AdV55, a newer genotype, was found in only one case.
  • Children infected with HAdV were typically older and exhibited more fever compared to those infected with RSV, although both groups had similar hospitalization durations.
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Objective: To investigate the prevalence and clinical characterization of HCoV-NL63 (NL63) in children with acute respiratory tract infections (ARTIs) in Lanzhou with other respiratory viruses. The prevalence of HBoV1 in ALRTI was obviously city,China.

Method: From November 2006 to October 2009,1169 nasopharyngeal aspirates (NPA) were collected from children under 14 years old with ARTIs.

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Objective: To investigate prevalence of Saffold virus (SAFV) in Changsha area of hospitalized children with respiratory tract infection, and to discuss whether this virus is related to respiratory tract infection of children.

Methods: 643 nasopharyngeal aspirates samples were collected from hospitalized children with respiratory tract infection of the first affiliated hospital of Hunan nomal university during Nov. 2007 to Oct.

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Objective: Human coronavirus (CoV)-HKU1 (HCoV-HKU1) was first isolated by Woo et al in Hong Kong. Several successive reports confirmed retrospectively that this new human coronavirus was circulating in different countries worldwide. However, the impact and the role of the emerging HCoV-HKU1 were not defined in children with ARTI.

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There are limited data on the prevalence and clinical and molecular characterization of human respiratory syncytial virus (HRSV) in children with acute respiratory tract infections (ARTIs) in China. From December 2006 to March 2009, 894 nasopharyngeal aspirates (NPAs) were collected from children under 14 years of age with ARTIs. Samples were screened for HRSV and genotyped by reverse transcription-PCR (RT-PCR) and sequencing.

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Background: Human CoV-HKU1 (HCoV-HKU1) has been isolated from a 71-year-old man with pneumonia; however, the impact and role of emerging HCoV-HKU1 have not been defined in children with acute respiratory tract infection (ARTI).

Objective: To investigate the Prevalence and clinical characteristics of HCoV-HKU1 in children with ARTI in Lanzhou, China.

Study Design: The reverse transcription polymerase chain reaction (RT-PCR) or PCR was employed to screen HCoV-HKU1 and other common respiratory viruses in 645 nasopharyngeal aspirate (NPA) specimens collected from children with ARTI from November 2006 to October 2008.

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Human bocavirus (HBoV) and HBoV2, two human bocavirus species, were found in 18 and 10 of 235 nasopharyngeal aspirates, respectively, from children hospitalized with acute respiratory tract infection. Our results suggest that, like HBoV, HBoV2 is distributed worldwide and may be associated with respiratory and enteric diseases.

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