Publications by authors named "Kiyoshi Ishii"

: Brown-McLean syndrome (BMS) is a rare peripheral corneal edema that may arise years after cataract extraction or intraocular lens (IOLs) fixation. This article presents a case of IOL dislocation following scleral fixation in a patient with BMS, effectively managed by resuturing the existing IOL. Additionally, a literature review was conducted to summarize the clinical features, etiologies, and surgical outcomes of BMS.

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Rationale: The objective of this study was to apply secondary intraocular lens (IOL) intrascleral fixation with lens capsule preservation in a patient with IOL dislocation following mature cataract surgery with incomplete continuous curvilinear capsulorhexis (CCC).

Patient Concerns: A 56-year-old Japanese woman experienced distorted vision 4 days after phacoemulsification and intracapsular IOL implantation for a mature cataract.

Diagnoses: Slit-lamp examination revealed inferior-nasal dislocation of the intracapsular IOL through an anterior capsule defect (3-6 o'clock) caused by peripheral extension of the CCC during the primary surgery.

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Minimally invasive glaucoma surgery (MIGS) is believed to induce less surgically induced astigmatism (SIA) due to smaller incisions, yet few studies have evaluated SIA in MIGS patients. This retrospective cohort study compared SIA and refractive outcomes among three MIGS techniques: first-generation trabecular micro-bypass stent (iStent [IS], n = 36), second-generation iStent inject W (IW, n = 39), and microhook ab interno trabeculotomy (μLOT, n = 36). SIA, refractive prediction error (RPE), intraocular pressure (IOP), and glaucoma subtype were analyzed.

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Purpose: This retrospective study compares the surgical outcomes of ab interno trabeculotomy using the Kahook Dual Blade (KDB) and Tanito microhook (TMH) combined with cataract surgery.

Patients And Methods: Twenty-four eyes from 19 and 17 patients with glaucoma in the KDB and TMH groups, respectively, were included. Background factors were matched for medication score and disease type using propensity scores.

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Purpose: Polyarteritis nodosa (PAN) is a systemic vasculitis of unknown etiology affecting medium- and small-sized arteries and can present with varied organ involvement, including ocular manifestations. Here, we report a unique case of PAN that initially presented with diplopia and ocular motility impairment, with subsequent development of bilateral central retinal artery occlusion (CRAO), a rare ocular manifestation of PAN.

Observations: A 58-year-old man presented with left abduction impairment and diplopia, which initially improved without intervention.

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Background: This study aimed to report and recall a simple method to remove the lens capsule ab externo when performing intrascleral fixation of an intracapsular intraocular lens (IOL) dislocation with reuse of the IOL.

Case Presentation: A 43-year-old Japanese male patient underwent pars plana vitrectomy, phacoemulsification, and IOL fixation for rhegmatogenous retinal detachment in the right eye 10 years prior. A 3-piece IOL was intraocularly fixed during the initial procedure.

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Article Synopsis
  • A 71-year-old woman developed serous retinal detachment (SRD) and ciliochoroidal detachment (CCD) following minimally invasive glaucoma surgery (MIGS) for primary open-angle glaucoma, which persisted for 2 years and 7 months.
  • After surgery, she experienced consistently low intraocular pressure (IOP), which contributed to increased choroidal thickness and SRD, leading to visual changes.
  • Eventually, after a spike in IOP, the detachments resolved, and her vision stabilized, indicating that prolonged CCD and low IOP post-MIGS may disrupt choroidal function and retinal health.
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Article Synopsis
  • - A 61-year-old woman experienced acute angle-closure glaucoma in her pseudophakic eye after undergoing a 25-gauge pars plana vitrectomy for a macular hole, despite initially having an uncomplicated surgery.
  • - The patient had to maintain a face-down position post-surgery, which, combined with gas tamponade, may have led to increased intraocular pressure and the development of glaucoma, characterized by a severe rise in pressure (53 mmHg) and iris bombe.
  • - The condition was treated successfully with a laser peripheral iridotomy, which helped lower the intraocular pressure and ultimately closed the macular hole, illustrating the complex post-operative scenarios that can arise in eye surgeries.
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Article Synopsis
  • - Three Japanese patients with pseudoexfoliation syndrome (PEX) successfully underwent intrascleral intraocular lens (IOL) fixation after challenges with traditional fixation methods due to zonular weakness.
  • - Each case utilized a double-needle technique for IOL fixation six to eight weeks after initial cataract surgery, with adjustments like anterior vitrectomy in case two to address complications.
  • - The procedure resulted in positive outcomes, with no serious complications; preserving the lens capsule during fixation helped reduce intraoperative risks and complications, though the long-term safety of this approach needs further investigation.
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Rationale: There are reports of safe cataract surgery in eyes with posterior polymorphous corneal dystrophy (PPCD); however, to our knowledge, there are no reports of minimally invasive glaucoma surgery (MIGS) in eyes with PPCD. Herein, we report a case of poor intraoperative visibility with gonioscopy, postoperative corneal edema, and corneal astigmatism in eyes with PPCD treated with trabecular micro-bypass stent combined with cataract surgery.

Patient Concerns/diagnosis: A 78-year-old man was referred to our hospital for MIGS.

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Purpose: To clarify the characteristics of intraocular lens (IOL) dislocation requiring IOL suture or intraocular scleral fixation.

Methods: This retrospective consecutive case series included 21 eyes (21 patients) who required sutured or sutureless intrascleral IOL fixation following IOL extraction owing to IOL dislocation at the outpatient clinic in the Department of Ophthalmology, Saitama Red Cross Hospital, Japan, between January and December 2019. Medical records were retrospectively reviewed for background diseases, location of the dislocated IOL (intracapsular/extracapsular), insertion of a capsular tension ring (CTR), and the period from IOL insertion to dislocation.

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Purpose: To investigate the relationship between intraocular pressure (IOP) and axial length (AL) and to compare the refractive predicted error in patients who have undergone cataract surgery alone or in combination with trabeculotomy.

Setting: Hospital.

Design: Single-center, retrospective, case-control.

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Purpose: This study evaluated the effectiveness and safety of first and revised second-generation trabecular microbypass stent insertion [iStent (IS) and iStent inject W (IW)] in cataract surgery.

Design: Single-center, retrospective, cohort study.

Methods: The study included 176 eyes that received trabecular microbypass stents combined with cataract surgery at the Saitama Red Cross Hospital between September 2017 and September 2021.

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Suprachoroidal effusion (SCE) is a rarely observed complication due to the recent generalization of clear corneal small-incision cataract surgery. We report a case of anterior chamber shallowing (ACS) from the early stage of surgery and SCE during clear corneal small-incision cataract surgery. A 69-year-old man was referred to our department for primary open-angle glaucoma and grade 2 nuclear cataract.

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Background: Severe intraocular hemorrhage is a rare complication of cataract surgery due to the recent generalization of minimal-incision cataract surgery. We report a case of a massive intraocular hemorrhage that probably originated from the central retinal artery after cataract surgery, in which hemostasis was difficult to achieve during vitrectomy.

Case Presentation: An 86-year-old woman was referred to our department for intraocular lens (IOL) dislocation after undergoing cataract surgery.

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To evaluate the effects of the discontinuation of antithrombotic drugs on intraocular pressure (IOP) reduction and complications from ab interno trabeculotomy for patients with glaucoma. We performed a retrospective chart review on the data of patients treated with antithrombotic agents who have undergone ab interno trabeculotomy through Tanito microhook combined with cataract surgery at the Asahi General Hospital and the Tokyo University Hospital, with 6 months of follow-up. The patients were classified into two groups depending on whether they discontinued (AT-) or continued (AT+) antithrombotic therapy during the perioperative phase.

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Background: Cytomegalovirus (CMV) has been known to cause unilateral corneal endotheliitis with keratic precipitates and localized corneal edema, iridocyclitis, and secondary glaucoma. CMV endotheliitis is diagnosed based on clinical manifestations and viral examination using qualitative polymerase chain reaction (PCR) of the aqueous humor.

Case Presentation: An 80-year-old woman was referred to our department for bullous keratopathy.

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OBJECTIVEThe objective of this study was to test the hypothesis that midline (interhemispheric or perimesencephalic) traumatic subarachnoid hemorrhage (tSAH) on initial CT may implicate the same shearing mechanism that underlies severe diffuse axonal injury (DAI).METHODSThe authors enrolled 270 consecutive patients (mean age [± SD] 43 ± 23.3 years) with a history of head trauma who had undergone initial CT within 24 hours and brain MRI within 30 days.

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Background: Persistent infection with high-risk human papillomavirus (HPV) is closely associated with cervical cancer development. In this study, the performance of the Clinichip HPV genotyping assay as a screening laboratory test for high-risk HPV infection was evaluated.

Methods: The genotypes of 74 cervical scrape specimens were tested using the Clinichip HPV assay and a conventionally employed HPV polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) assay.

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Intraventricular hemorrhage (IVH) on initial computed tomography (CT) was reported to predict lesions of diffuse axonal injury (DAI) in the corpus callosum (CC) on subsequent magnetic resonance imaging (MRI). We aimed to examine the relationship between initial CT findings and DAI lesions detected on MRI as well as the relationship between the severity of IVH (IVH score) and severity of DAI (DAI staging). A consecutive 140 patients with traumatic brain injury (TBI) who underwent MRI within 30 days after onset were revisited.

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Rationale And Objectives: Computed tomography (CT) plays a crucial role in early assessment of patients with traumatic brain injury (TBI). Marshall and Rotterdam are the mostly used scoring systems, in which CT findings are grouped differently. We sought to determine the scoring system and initial CT findings predicting the death at hospital discharge (early death) in patients with TBI.

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