Fluorescence on the Flow: Continuous Xanthene Dye Synthesis from Gallic Acid in a Coiled Flow Inverter.

Transparent coiled flow inverters (CFI), which are superior to opaque coil reactors, are hardly explored in performing condensation reactions of organic molecules. Herein, the continuous flow condensation reaction of gallic acid using CFI is reported with a 4 mm internal diameter. The length of the flow reactor is varied by connecting CFIs in series.

Risk at the Crossroads: Evaluating the Risk of Sexually Transmitted Infections in High-Risk Groups.

Background: Sexually transmitted infections (STIs) continue to pose a serious public health challenge globally, including in India. With over one million new cases reported annually, inadequate testing and screening remain significant barriers to controlling and ultimately eliminating STI transmission. Men who have sex with men (MSMs), transgender individuals (TGs), female sex workers (FSWs), and injecting drug users (IDUs) are widely recognized as experiencing higher infection rates.

Single nucleotide polymorphism and expression of P16 gene as a potential biomarker for oral and pre-oral cancer.

Objective: This study investigated the association between p16 gene and its 450 C > G (rs11515) polymorphism with risk of oral cancer and precancerous oral lesions/oral potentially malignant disorder (OPMD).

Method: The study included 230 individuals with OPMD conditions (70 with leukoplakia, 90 with oral submucous fibrosis, and 70 with lichen planus), 72 oral cancer patients, and 300 cancer-free healthy controls. Genotyping of the p16 450 C > G polymorphism was conducted using PCR-RFLP methods, and genotype and allele frequencies were analyzed using chi-square test.

Adopting drone technology for blood delivery: a feasibility study to evaluate its efficiency and sustainability.

Background: Understanding what drives effective implementation is the key to making more sustainable developments. Blood and its components are critical for life-saving transfusions, however, their availability at the point of care is often limited. Moreover, the logistical challenges associated with blood product transport are substantial and maintaining the cold chain throughout the supply route is crucial to sustain their functional integrity as the temperature fluctuations can compromise its oxygen-carrying capacity.

Investigating the effects of microwave plasma on bacterial cell structures, viability, and membrane integrity.

Plasma-mediated bacterial inactivation holds great promise but presents several challenges. This study investigates the antibacterial effect of 2.45 GHz non-thermal microwave (MW) plasma on Staphylococcus aureus (S.