Copper-Catalyzed Carbonylative Cyclization of CO: A Promising Approach for Synthesis of Flavone.

Flavones are an important class of building blocks for numerous biologically active molecules, pharmaceuticals, and natural products. Reductive carbonylation of CO is a powerful method to provide high-value heterocycles quickly. However, examples of transition metal-catalyzed carbonylation to produce flavones using CO are quite scarce, and the related copper-catalyzed carbonylative cyclization of CO is not reported.