Publications by authors named "Jun-Qing Lin"
Purpose: The aim of this study was to assess the safety and effectiveness of transarterial chemoembolization (TACE) plus lenvatinib with a programmed death-1 (PD-1) inhibitor compared with TACE plus lenvatinib and TACE alone for hepatocellular carcinoma (HCC) with the hepatic vein and/or inferior vena cava tumor thrombus (HVTT and IVCTT).
Methods: Data on HCC accompanied by HVTT and IVCTT from June 2015 to August 2022 were analyzed in this single-center retrospective study. Drug-eluting bead TACE (DEB-TACE) or conventional TACE (cTACE) was used.
Article Synopsis
- This study evaluates the effectiveness and safety of a combined therapy (TACE + lenvatinib + PD-1 inhibitor + iodine-125 brachytherapy) for HCC patients with portal vein tumor thrombosis compared to other approaches.
- The research analyzed data from 150 patients to measure outcomes like overall survival (OS) and progression-free survival (PFS), finding that the combined therapy significantly improved these metrics.
- The results showed that the combined treatment group had a noticeably longer OS and PFS compared to other treatment groups, with no significant differences in adverse events reported.
Article Synopsis
- The study investigated the impact of pirfenidone (PFD) and 2-methoxyestradiol (2-ME2) perfusion on liver fibrosis caused by hepatic artery hypoxia in rats.
- The results showed that PFD significantly improved liver fibrosis by reducing levels of certain proteins and genes associated with liver damage, indicating a positive effect on liver health.
- However, adding 2-ME2 to the treatment did not enhance the benefits provided by PFD alone, suggesting that PFD is the more effective therapy in this context.
Background: The purpose of this study was to assess the safety and efficacy of percutaneous transcatheter embolization (TCE) for the treatment of pulmonary arteriovenous malformations (PAVMs).
Methods: Forty-three consecutive patients (n = 17 males; n = 26 females) with 72 untreated PAVMs underwent coil and/or plug embolization between January 2010 and February 2018. The mean patient age was 42 ± 14 years (range 19-71 years).
Background: Displaced patellar fractures are commonly treated with open reduction and fixation with several different types of tension-band (TB) constructs. The main objective of this study was to compare the prevalence of postoperative complications after surgical stabilization of comminuted patellar fractures with either a modified Kirschner-wire tension band (MKTB), a cannulated-screw tension band (CSTB), or a ring-pin tension band (RPTB).
Methods: We conducted a retrospective and consecutive cohort study of comminuted patellar fractures (n = 334) stabilized using a TB construct.
Objective: A molecular biology method was studied to identify medical Dendrobium and to provide a method for quality control of these plants.
Method: ISSR primer was screened through ISSR-PCR reaction according to its gene resolving power, and digital barcodes were established for identification.
Results: Screening 2 primers which Rp value above 8, This primers can identify medical Dendrobium from 6 kinds 8 groups.