Publications by authors named "Jun-Cheng Yu"
Background: Neoadjuvant chemoimmunotherapy demonstrates favorable survival outcomes and high pathological complete response (pCR) rates, but its efficacy in resectable N1/N2 non-small cell lung cancer (NSCLC) remains unproven. Additionally, predictive biomarkers for treatment efficacy and the relationship between lymph node status post-neoadjuvant therapy and survival are unclear. This prospective study evaluates the efficacy and safety of combining penpulimab with chemotherapy for resectable N1/N2 NSCLC.
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- This study compared the effectiveness and cost-utility of two surgical methods, unilateral biportal endoscopy (UBE) and percutaneous endoscopic interlaminar discectomy (PEID), for treating single-level lumbar disc herniation (LDH) in 99 patients.
- Both surgical techniques showed significant improvements in pain and function after surgery, but UBE required more operative time and had higher nursing costs compared to PEID.
- Despite these higher costs and complications, UBE demonstrated a better cost-utility profile with a calculated incremental cost-effectiveness ratio of $354.5 per quality-adjusted life year (QALY) gained, indicating it may offer better overall value.
T1-Weighted Imaging-Based Hippocampal Radiomics in the Diagnosis of Alzheimer's Disease.
Acad Radiol
December 2024
Rationale And Objectives: To investigate the potential of T1-weighted imaging (T1WI)-based hippocampal radiomics as imaging markers for the diagnosis of Alzheimer's disease (AD) and their efficacy in discriminating between mild cognitive impairment (MCI) and dementia in AD.
Methods: A total of 126 AD patients underwent T1WI-based magnetic resonance imaging (MRI) examinations, along with 108 age-sex-matched healthy controls (HC). This was a retrospective, single-center study conducted from November 2021 to February 2023.
Role of Pre-Operative Nutrition Status on Surgical Site Infection After Posterior Lumbar Interbody Fusion: A Retrospective Study.
Surg Infect (Larchmt)
December 2023
A retrospective case-control study to determine the role of pre-operative systemic and local nutritional factors on patients developing a surgical site infection (SSI) after posterior lumbar interbody fusion (PLIF). Surgical site infection after PLIF remains a substantial cause of morbidity. The literature demonstrates the prognosis of surgical patients is associated with pre-operative nutritional status that not only includes systemic nutritional factors, such as prognostic nutritional index (PNI), body mass index (BMI), and serum albumin, but also local nutritional factors, such as subcutaneous fat thickness at the surgical site, including absolute fat thickness and relative fat thickness.
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