Publications by authors named "Juan D Duque"

Background: Although the diagnosis of Borderline Personality Disorder (BPD) during adolescence has been questioned, many recent studies have confirmed its validity. However, some clinical manifestations of BPD could be identifiable in adolescents with other pathologies, such as Attention-Deficit/Hyperactivity Disorder (ADHD). The objective of the present study is to examine the capacity of the self-report Borderline Personality Features Scale Children-11 (BPFSC-11) to discriminate between BPD and ADHD adolescents.

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Article Synopsis
  • Researchers have found changes in cerebellar structure in children with autism, ADHD, and developmental coordination disorder, but it's unclear if these changes are common across conditions or specific to each disorder.
  • The study analyzed MRI scans from 252 children aged 7 to 12, focusing on the grey matter volume of 27 cerebellar lobules using a voxel-wise approach.
  • Results showed that children with ADHD had lower grey matter volume in a specific cerebellar region compared to controls, but this finding wasn't significant when accounting for medication status, and no notable differences were found in children with ASD or DCD.
  • Future research aims to combine behavioral data to further investigate differences and similarities across these neurodevelopmental disorders.
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Diffusion MRI has provided the neuroimaging community with a powerful tool to acquire in-vivo data sensitive to microstructural features of white matter, up to 3 orders of magnitude smaller than typical voxel sizes. The key to extracting such valuable information lies in complex modelling techniques, which form the link between the rich diffusion MRI data and various metrics related to the microstructural organization. Over time, increasingly advanced techniques have been developed, up to the point where some diffusion MRI models can now provide access to properties specific to individual fibre populations in each voxel in the presence of multiple "crossing" fibre pathways.

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