Publications by authors named "Jose Pedro Rocha"
Electrochemical Magnetic Immunoassay for the Determination of the Fish Allergen β-Parvalbumin.
Biosensors (Basel)
December 2024
β-parvalbumin (β-PV) is the primary fish allergen responsible for most allergic reactions in individuals sensitive to fish. To ensure food safety, a sandwich-based magnetic immunoassay was developed using maleimide-functionalized magnetic beads (NH-MBs). Specific anti-β-PV antibodies were immobilized on these MBs, and a screen-printed carbon electrode was employed as the electrochemical transducer.
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- This study investigates how plasma brain-derived tau (BD-Tau) can predict outcomes for patients with acute ischemic stroke who undergo endovascular therapy (EVT), potentially improving prognosis after EVT trials initiated in 2015.
- Two independent patient cohorts with large vessel occlusion were analyzed, measuring various plasma biomarkers pre- and post-EVT, with 90-day functional outcomes assessed using standardized scales.
- Results show that while GFAP was strong for early imaging outcomes, BD-Tau was more effective for predicting long-term functional recovery, leading to the development of a predictive model that proved effective across both cohorts.
Seafood product labels with accurate allergen contents can avoid and/or minimize allergic reactions. Therefore, an electrochemical immunosensor for the analysis of β-parvalbumin (β-PV, a major fish allergen) was developed. Screen-printed carbon electrodes were nanostructured with reduced graphene oxide and gold nanoparticles.
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