One Health clinic challenges and evolution: increasing access to care for people and pets in a rural community in Northern California.

A student-run, free One Health clinic (OHC) improves access to care for people and pets while providing increased training opportunities for interprofessional students in the areas of spectrum of care, contextualized care, cultural humility, ethical community engagement, and relationship-centered communication when clinical instruction is provided. The coordination and implementation of a community-based student-run free clinic (SRFC) that is also an OHC is complex. Programmatic challenges can include coordination with the leaders of multiple training programs, seasonal variation of student and clinical instructor schedules, and the need to balance student experiential learning with positive client and patient outcomes.

Case report: Clinical and immunohistochemical manifestations of suspected Sjogren's disease in a dog.

Sjogren's disease, well-described in people, is rarely identified in veterinary species. In people, Sjogren's disease is one of the most common systemic autoimmune disorders with an incidence of 0.5% in the female population.

Evaluation of the efficacy of a live Escherichia coli biotherapeutic product (asymptomatic bacteriuria E. coli 212).

Background: Recurrent bacterial cystitis, often referred to as recurrent urinary tract infection (UTI), can be difficult to manage and alternative treatments are needed.

Hypothesis/objective: Intravesicular administration of asymptomatic bacteriuria (ASB) E. coli 212 will not be inferior to antimicrobial treatment for the management of recurrent UTI in dogs.

The Diverse Pathogenicity of Various Parasite Species That Infect Dogs.

species infect a very wide range of mammal hosts across the globe, and zoonotic infections are of growing concern. Several species of the genus infect dogs, and some of these cause significant morbidity and mortality. The Apicomplexan parasite resides within the red cell and infections result in direct damage to the host through intra- and extravascular hemolysis.

Polyautoimmunity manifest as inflammatory myopathy, uveitis, and progressive cutaneous depigmentation in a mixed breed dog: a case report.

Background: Polyautoimmunity is the expression of more than one autoimmune disease in a single patient. This report documents polyautoimmunity in a mixed breed dog with concurrent uveitis, cutaneous depigmentation, and inflammatory myopathy.

Case Presentation: A 1-year-old male neutered mixed breed dog was presented for progressive generalized leukotrichia and leukoderma, bilateral panuveitis, and masticatory muscle atrophy.

Hypoadrenocorticism in a Dog Following Recovery from Alpha-Amanitin Intoxication.

A 10-year-old, female spayed Labrador Retriever was referred for acute hepatopathy and urinary retention. Blood work from the initial presentation (day 0) revealed a severe, mixed hepatopathy. Over the course of the patient's hospitalization, the patient developed liver insufficiency.

Prevalence of antibiotic use for dogs and cats in United States veterinary teaching hospitals, August 2020.

Background: Awareness of prescribing practices helps identify opportunities to improve antibiotic use (AU).

Objectives: To estimate AU prevalence in dogs and cats in U.S.

Evaluation of a rapid immunoassay for bacteriuria in dogs.

Background: The ability to detect bacteriuria in dogs with a point-of-care test might improve medical care and antimicrobial stewardship.

Hypothesis And Objective: A rapid immunoassay (RIA; RapidBac) will provide acceptable sensitivity and specificity for diagnosis of bacteriuria.

Animals: Forty-four client-owned dogs with a clinical indication for urinalysis and aerobic bacterial urine culture.

Babesia in North America: An Update.

Canine babesiosis results from infection of 1 of 5 identified protozoal species in the United States (Babesia conradae, Babesia sp. "coco," Babesia gibsoni, Babesia vogeli, and Babesia vulpes). They are part of the Apicomplexa family of protozoa and are obligate intraerythrocytic parasites.

Pharmacokinetics of isavuconazole in healthy cats after oral and intravenous administration.

Background: Isavuconazole is a triazole antifungal drug that has shown good efficacy in human patients. Absorption and pharmacokinetics have not been evaluated in cats.

Objectives: To determine the pharmacokinetics of isavuconazole in cats given a single IV or PO dose.

Assessment of Zoonotic Risk following Diagnosis of Canine Tularemia in a Veterinary Medical Teaching Hospital.

Tularemia is a rare zoonotic disease found worldwide. The agent responsible for disease, , is one of the most highly infectious pathogens known, one that is capable of causing life-threatening illness with inhalation of <50 organisms. High infectivity explains concerns of its use in bioterrorism.

Disseminated Rasamsonia argillacea species complex infections in 8 dogs.

Background: Clinical features, treatment, and outcome of opportunistic infections with Rasamsonia spp., a nonpigmented filamentous mold, are not well documented in dogs.

Objectives: Describe clinical, radiographic, pathologic features, and outcome of dogs with disseminated Rasamsonia species complex infections.

A preliminary study on assessment of wellbeing among veterinary medical house officers.

Mental wellness is an important topic among practicing veterinarians. Peer reviewed studies focusing on veterinary house officers' wellbeing are lacking in veterinary medicine. The aim of this study was to assess wellbeing of house officers using validated surveys for anxiety, burnout, depression, and quality of life.

Quality of DNA extracted from formalin-fixed, paraffin-embedded canine tissues.

Veterinary pathology tissue banks are valuable resources for genetic studies. However, limited data exist as to whether quality DNA can be extracted from these tissues for use in canine genotyping studies. We extracted DNA from 44 formalin-fixed, paraffin-embedded (FFPE) tissue blocks from dogs; 9 of these dogs had DNA available from whole blood samples that had been banked.

Bacterial Pneumonia in Dogs and Cats: An Update.

Bacterial pneumonia is a common clinical diagnosis in dogs but seems to occur less often in cats. Underlying causes include viral infection, aspiration injury, foreign body inhalation, and defects in clearance of respiratory secretions. Identification of the specific organisms involved in disease, appropriate use of antibiotics and adjunct therapy, and control of risk factors for pneumonia improve management.

Evaluation of a dry therapeutic urinary diet and concurrent administration of antimicrobials for struvite cystolith dissolution in dogs.

Background: Struvite urolithiasis with bacterial urinary tract infection (UTI) is commonly reported in dogs; few data exist to describe successful dissolution protocols in dogs with naturally occurring disease. We hypothesized that a dry therapeutic urinary diet combined with targeted antimicrobial therapy can effectively dissolve presumptive struvite cystolithiasis in dogs with naturally occurring urease-producing bacterial UTI.

Results: Ten dogs with presumed infection-induced struvite cystolithiasis based on lower urinary tract signs (LUTS), radiodense cystoliths, and urease-producing bacterial UTI were enrolled.

Risk factors for Candida urinary tract infections in dogs and cats.

Background: Candida urinary tract infections occur in both dogs in cats but there is limited data about risk factors.

Objective: To identify risk factors for candiduria in dogs in cats.

Animals: Eighteen dogs and 8 cats with candiduria.

Clinical one health: A novel healthcare solution for underserved communities.

Limited access to healthcare is a symptom of poverty worldwide. In Knights Landing, California, USA, an economically underserved, agricultural community, advocates recognized that integration of human and animal healthcare could provide a less intimidating gateway to services and facilitate assessments of individuals' health, not just in moments in time, but within the context of the complex interactions with other humans, animals, and their encompassing environment. Humans and animals share diseases resulting from common exposure to environmental pollutants and disease hosts and lack of adequate nutrition.

Babesia conradae infection in coyote hunting dogs infected with multiple blood-borne pathogens.

Background: Babesia conradae is an intraerythrocytic piroplasm infecting dogs in the southern United States. Ticks have been suspected, but unproven, as vectors. We identified B.

A multidisciplinary, minimally invasive approach combining lacrimoscopy and fluoroscopically guided stenting for management of nasolacrimal apparatus obstruction in dogs.

OBJECTIVE To describe and evaluate outcomes of a multidisciplinary, minimally invasive approach combining lacrimoscopy and fluoroscopically guided stenting for management of nasolacrimal apparatus (NLA) obstruction in dogs. DESIGN Prospective, nonrandomized clinical trial. ANIMALS 16 client-owned dogs with confirmed NLA obstruction.

Bacterial pneumonia in dogs and cats.

Bacterial pneumonia is a common clinical diagnosis in dogs but seems to occur less commonly in cats. Underlying causes include viral infection, aspiration injury, and foreign body inhalation. Identification of the organisms involved in disease, appropriate use of antibiotics and adjunct therapy, and control of risk factors for pneumonia improve management.