Metabolomic and partial proteomic analyses of phosphine resistance in Sitophilus oryzae adults: Significant reduction in body weight after acquiring resistance.

Fumigation with phosphine (PH), the toxicity of which is related to reactive oxygen species (ROS) generation, is widely used to control insect pests such as Sitophilus oryzae in stored commodities. However, overuse and misuse of PH fumigation have led to severe resistance in the targeted insect pests, including S. oryzae.

Acute and neurological toxicities of endosulfan I, endosulfan sulfate, endosulfan diol, and endosulfan ether in zebrafish (Danio rerio) embryos: Developmental effects on heart and brain formation.

Endosulfan (ES) is classified as a persistent organic pollutant (POP), and its use has been banned in the agricultural sectors of most countries. It is metabolized into several compounds, among which ES sulfate is frequently detected in the environment. In this study, the acute toxicities of α-ES, ES sulfate, ES diol, and ES ether were evaluated in zebrafish (Danio rerio) embryos.