Publications by authors named "Jingwen Chu"
Article Synopsis
- - The study assessed the safety and effectiveness of combining camrelizumab and apatinib in patients with advanced esophageal squamous cell carcinoma (ESCC) who previously received immune checkpoint inhibitors (ICIs).
- - Out of 49 patients treated, the confirmed objective response rate was 10.2%, with a disease control rate of 69.4% and median progression-free survival of 4.6 months.
- - The results indicated that the response rate was modest and did not show significant improvement, though the treatment had a manageable safety profile with no treatment-related deaths reported.
Cellular senescence has a complex role in lymphocyte carcinogenesis and drug resistance of lymphomas. Senescent lymphoma cells combine with immunocytes to create an ageing environment that can be reprogrammed with a senescence‑associated secretory phenotype, which gradually promotes therapeutic resistance. Certain signalling pathways, such as the NF‑κB, Wnt and PI3K/AKT/mTOR pathways, regulate the tumour ageing microenvironment and induce the proliferation and progression of lymphoma cells.
View Article and Find Full Text PDFObjectives: Recently, there has been extensive research on dual immunotherapy for advanced or metastatic non-small cell lung cancer (NSCLC), yet a comprehensive evaluation is lacking. This study aimed to rank the available treatment options and assess the efficacy and safety of dual immunotherapy regimens through the implementation of a Bayesian network meta-analysis (NMA).
Materials And Methods: A thorough search was conducted to recognize eligible randomized controlled trials (RCTs) on March 20, 2023.
Graphene-Based Materials as Strain Sensors in Glass Fiber/Epoxy Model Composites.
ACS Appl Mater Interfaces
August 2019
Article Synopsis
- The study explored the effectiveness of graphene-based materials as strain sensors in composite materials, specifically looking at graphene nanoplatelets (GNPs) versus CVD-grown graphene using Raman spectroscopy.
- The thicker GNPs exhibited lower strain sensitivity due to their poor interaction with fibers and inconsistent properties leading to variable strain reports.
- In contrast, CVD graphene showed superior strain sensing performance, providing accurate and reliable readings at low strain levels while revealing interfacial sliding at higher strains.