Fe-N@Graphene Single-Atom Catalyst-Based Nanozyme against Influenza A Virus.

Recent COVID-19 pandemic has raised an urgent need for effective strategies to combat viruses that can pose serious health threats to the entire human race. Incorporating antipathogenic functions into everyday objects and personal protective equipment has become increasingly important, motivating the development of general-purpose antiviral materials. Single-atom catalysts, known for superior catalytic performance and maximized atomic utilization, have been explored in various research fields, including artificial nanozymes for bioapplications.

Study protocol for a prospective, randomized controlled confirmatory clinical investigation to evaluate the safety and efficacy of a multidisciplinary digital therapeutics in patients with patellofemoral pain syndrome.

Background: Patellofemoral pain is a prevalent knee condition affecting up to 40% of individuals, especially females aged teens to 50 s. Standard treatments, including exercise therapy, often yield insufficient long-term results, partly due to low compliance and psychological factors like depression and catastrophizing of pain. A digital therapeutics "MORA Cure PFP," which combines structured progressive exercise and cognitive behavioral therapy via an app, offers a solution to overcome the limitations of conventional treatment for patellofemoral pain patients.

Surface Tension-Driven Self-Planarization of MXene Liquid Crystalline Fiber for High-Performance Energy Storage.

2D MXene-based liquid crystalline (LC) systems have emerged as promising precursors for constructing highly ordered functional materials, such as fibers, films, and aerogels via solution-based processing. In this study, we demonstrate surface tension-mediated self-planarization of MXene LC fibers by adjusting the solvent composition during wet-spinning, targeting improved electrochemical performance. Ethanol, a poor solvent for MXene, induced spontaneous parallel alignment of MXene platelets and facilitated densification into a ribbon-like geometry during coagulation.

Serial Changes in Muscle Strength and Dynamic Balance After Lateral Meniscal Allograft Transplantation: A Retrospective Cohort Study of 55 Patients.

Background: Despite numerous studies examining subjective clinical scores after meniscal allograft transplantation (MAT), research focusing specifically on functional measures is lacking.

Purpose: To evaluate the serial changes in isokinetic muscle strength and dynamic balance during the first postoperative year after lateral MAT (LMAT).

Study Design: Cohort study; Level of evidence, 3.

Surface Energy Tailored Reduced Graphene Oxide Top-Coat for Vertical Alignment of High-χ Block Copolymers for Sub-10-nm Nanopatterning.

Vertically aligned nanopatterns of high Flory-Huggins parameter (χ) block copolymers (BCPs) are desirable for effective pattern transfer of sub-10-nm scale self-assembled morphologies. To this end, BCP thin film is required to interface with neutralized surface energy at both substrate and free-surface, among which neutralization of top free-surface is generally more difficult without well-defined substrate geometry. Therefore, various types of top-coat layers have been developed, many of which, however, require complex synthetic processes or specifically designed equipment.

Clinical and Radiological Outcomes of Medial Meniscal Allograft Transplantation Combined With Realignment Surgery.

Background: The outcomes of medial meniscal allograft transplantation (MMAT) combined with high tibial osteotomy (HTO) compared with isolated MMAT remain unclear.

Purpose: To compare the clinical and radiological results of MMAT combined with HTO and isolated MMAT.

Study Design: Cohort study; Level of evidence, 3.

Reduced physiological extrusion of the medial meniscus in axial load-bearing condition in anterior cruciate ligament deficiency.

Purpose: In this study, ultrasonography was used to measure medial meniscus (MM) extrusion under weight-bearing and nonweight-bearing conditions in both anterior cruciate ligament (ACL)-deficient and ACL-intact knee groups. This study aimed to determine the possible differences between these groups with an eventual impact on meniscal tears in ACL-deficient knees.

Methods: A total of 107 patients who underwent ACL reconstructive surgery between June 2022 and April 2023 were enroled.

Collagen Meniscal Scaffold Implantation Can Provide Meniscal Regeneration in Asian Patients with Partial Meniscal Defects: A Prospective Randomized Controlled Study with Three-Dimensional Volume Analysis of the Meniscus.

Background: To date, the efficiency of collagen meniscal scaffold implantation in Asian patients with partial meniscal defects has not been evaluated. In addition, no study has quantitatively analyzed meniscal regeneration using three-dimensional (3D) volume analysis after collagen scaffold implantation. We aimed to compare meniscal regeneration using 3D volume analysis between Asian patients undergoing collagen-based meniscal scaffold implantation after partial meniscectomy and those undergoing only partial meniscectomy.

Sunlight-Driven Self-Cleaning Ultrafine Particulate Matter Filter with Antibacterial Activity.

Air pollution by particulate matter (PM) and airborne pathogens causes severe health problems in the human body. Presently, popular disposable air filters yield huge waste and have a fatal impact on the environment. Postuse cleaning of air filters also leads to secondary air and water pollution.

Single-incision bone bridge lateral meniscus allograft transplantation: preserving neurovascular safety with promising results for posterior horn distortion and graft maturation.

Purpose: This study aimed to investigate the graft maturation and safety of single-incision bone bridge lateral meniscus allograft transplantation (LMAT).

Methods: This study involved 35 patients who underwent LMAT between 2019 and 2020. All patients completed at least 2 years of follow-up (median 34 months; range 24-43) and underwent preoperative magnetic resonance imaging (MRI) to assess the trajectory safety of the leading suture passer and all-inside suture instrument (Fast-Fix).

Rehabilitation after Repair of Medial Meniscus Posterior Root Tears: A Systematic Review of the Literature.

Background: There is no consensus established on postoperative rehabilitation after medial meniscus posterior root tear (MMPRT) repair, including when and how physicians can apply range of motion (ROM) exercise, weight-bearing (WB), brace use, and return to sports (RTS). The purpose of this study was to systematically review the literature on postoperative rehabilitation characteristics of MMPRT repair regarding ROM, WB, brace use, and RTS.

Methods: A literature search was performed using the Medline/PubMed, Cochrane Central Register of Controlled Trials, and Embase databases.

Comparison of ACL and Anterolateral Ligament Reconstruction With Isolated ACL Reconstruction Using Hamstring Autograft: Outcomes in Young Female Patients With High-Grade Pivot Shift.

Background: Inferior return to sports (RTS) and functional outcomes have been reported in women after anterior cruciate ligament reconstruction (ACLR).

Purpose/hypothesis: The purpose was to evaluate the results of combined ACLR and anterolateral ligament reconstruction (ALLR) in young women with a high-grade pivot shift (grade ≥2). It was hypothesized that combined ACLR and ALLR would result in better RTS and rotational stability than isolated ACLR.

2D Materials Beyond Post-AI Era: Smart Fibers, Soft Robotics, and Single Atom Catalysts.

Recent consecutive discoveries of various 2D materials have triggered significant scientific and technological interests owing to their exceptional material properties, originally stemming from 2D confined geometry. Ever-expanding library of 2D materials can provide ideal solutions to critical challenges facing in current technological trend of the fourth industrial revolution. Moreover, chemical modification of 2D materials to customize their physical/chemical properties can satisfy the broad spectrum of different specific requirements across diverse application areas.

Direct Solution-Phase Synthesis and Functionalization of 2D WSe for Ambient Stability.

2H phase tungsten diselenide (WSe ) is a p-type 2D semiconductor from the transition metal dichalcogenides (TMDs) family with unique optoelectrical properties. Solution phase production of atomically thin WSe is challenging due to its instability under ambient conditions. We present a highly efficient and scalable solution method for simultaneously exfoliating and functionalizing WSe by leveraging the non-covalent interaction between mercapto-group and bulk WSe .

Additional Anterolateral Ligament Reconstruction Helps Patients Improve Dynamic Postural Stability in Revision Anterior Cruciate Ligament Reconstruction.

: The goal in treating anterior cruciate ligament (ACL) injury especially in revision cases is return to sports activity by regaining dynamic postural stability. Among various methods to achieve this goal, additional anterolateral ligament reconstruction (ALLR) is gaining attention. The purpose of this study was to evaluate the effects of additional ALLR in revision ACL reconstruction (RACLR).

Scalable Solution Phase Synthesis of 2D Siloxene a Two-Step Interlayer Expansion Process.

Two-dimensional (2D) siloxene is attracting considerable research interest recently principally owing to its inherent compatibility with silicon-based semiconductor technology. -The synthesis of siloxene has been mostly limited to multilayered structures using traditional topochemical reaction procedures. Herein, we report high-yield synthesis of single to few-layer siloxene nanosheets by developing a two-step interlayer expansion and subsequent liquid phase exfoliation procedure.

Correlation of Y Balance with Clinical Scores and Functional Tests after Anterior Cruciate Ligament Reconstruction in Young and Middle-Aged Patients.

Background: Criteria for return to sports (RTS) following anterior cruciate ligament (ACL) reconstruction have been extensively studied. But there is no consensus among investigators regarding which factors are most important in determining a safe RTS.

Methods: Sixty-one patients who underwent ACL reconstruction were included.

Effects of Neuromuscular Electrical Stimulation and Blood Flow Restriction in Rehabilitation after Anterior Cruciate Ligament Reconstruction.

The present study aimed to examine and compare the effects of a rehabilitation exercise (RE) using neuromuscular electrical stimulation (NMES) and blood flow restriction (BFR) on muscle function and knee functional abilities in patients who underwent anterior cruciate ligament reconstruction (ACLR). A total of 45 patients who underwent ACLR (28.76 ± 0.

Changes in Bone Marrow Lesions Following Root Repair Surgery Using Modified Mason-Allen Stitches in Medial Meniscus Posterior Root Tears.

Root repair can prevent osteoarthritis (OA) by restoring hoop tension in medial meniscus posterior root tears (MMPRTs). This study aims to investigate bone marrow edema (BME) lesions known to be associated with OA following MMPRTs. : Thirty patients with transtibial pull-out repair were recruited.

Effect of Preoperative Joint Space Width on Lateral Meniscal Allograft Transplantation: Outcomes at Midterm Follow-up.

Background: It remains unclear whether lateral joint space narrowing without severe cartilage loss before meniscal allograft transplantation (MAT) affects clinical outcomes and graft extrusion.

Hypothesis: Patients with greater preoperative joint space narrowing would show more graft extrusion, more osteoarthritis progression, and worse clinical outcomes than would those with less narrowing.

Study Design: Case-control study; Level of evidence, 3.

An Increasing Trend in the Number of Anterior Cruciate Ligament Reconstruction in Korea: A Nationwide Epidemiologic Study.

Background: Most epidemiologic studies of anterior cruciate ligament reconstruction (ACLR) to date have been conducted in Western populations, whereas no studies have been conducted in Asian populations. In this study, the incidence and trend of ACLR in Korea were investigated through an epidemiological big data analysis.

Methods: The data were collected by the Health Insurance Review and Assessment Service from 2008 to 2016 in Korea.

How to Perform Concomitant Medial Meniscus Pull-Out Repair With Medial Open-Wedge High Tibial Osteotomy Without Technical Failure.

Varus alignment of the knee joint (varus >5°) is known as a poor prognostic factor for medial meniscus root repair, and alignment correction is recommended in patients with varus deformity and medial meniscus root tears. However, simultaneous medial meniscus pull-out repair and high tibial osteotomy are technically demanding procedures due to the long surgical time, poor visualization, and breaking of the pull-out sutures during high tibial osteotomy procedures. In the present Technical Note, we will introduce a surgical method to perform 2 procedures simultaneously without technical difficulty.

Molecular-Level Lubrication Effect of 0D Nanodiamonds for Highly Bendable Graphene Liquid Crystalline Fibers.

Graphene fiber is emerging as a new class of carbon-based fiber with distinctive material properties particularly useful for electroconductive components for wearable devices. Presently, stretchable and bendable graphene fibers are principally employing soft dielectric additives, such as polymers, which can significantly deteriorate the genuine electrical properties of pristine graphene-based structures. We report molecular-level lubricating nanodiamonds as an effective physical property modifier to improve the mechanical flexibility of graphene fibers by relieving the tight interlayer stacking among graphene sheets.

Patients with advanced lateral osteoarthritis can return to sports and work after distraction arthroplasty plus lateral meniscal allograft transplantation combined with cartilage repair.

Purpose: This study aimed to report return to sports (RTS) and return to work (RTW) outcomes after distraction arthroplasty (DA) plus lateral meniscal allograft transplantation (MAT) combined with cartilage repair in active patients with advanced osteoarthritis. It was hypothesised that DA combined with lateral MAT would improve clinical and radiological outcomes and enable RTS and RTW for most patients.

Methods: In total, 21 patients with advanced osteoarthritis (moderate to severe joint space narrowing at lateral edge on Rosenberg view and large cartilage defect of lateral femoral condyle) who underwent concomitant DA and MAT were retrospectively reviewed.

Monodisperse Carbon Nitride Nanosheets as Multifunctional Additives for Efficient and Durable Perovskite Solar Cells.

Two-dimensional (2D) materials are promising components for defect passivation of metal halide perovskites. Unfortunately, commonly used polydisperse liquid-exfoliated 2D materials generally suffer from heterogeneous structures and properties while incorporated into perovskite films. We introduce monodisperse multifunctional 2D crystalline carbon nitride, poly(triazine imide) (PTI), as an effective defect passivation agent in perovskite films via typical solution processing.