Publications by authors named "Jiao-Yan Mao"

We investigated the responses of soil extracellular enzyme activities and stoichiometric characteristics following the conversion of mixed conifer-broadleaf forest to plantation in the subtropical region. The results showed that the conversion from natural forest to plantation significantly reduced activities of cellulose hydrolase (CBH), β-D-glucosidase (βG), β-N-acetylglucosaminidase (NAG), acid phosphatase (AP) by 70.6%, 53.

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Ferroptosis is a unique cell death mode that relies on iron and lipid peroxidation (LPO) and is extensively utilized to treat drug-resistant tumor. However, like the other antitumor model, requirement of oxygen limited its application in treating the malignant tumors in anaerobic environments, just as photodynamic therapy, a very promising anticancer therapy. Here, we show that an iridium(III) complex (Ir-dF), which was often used in proton-coupled electron transport (PCET) process, can induce efficient cell death upon photo irradiation, which can be effectively protected by the typical ferroptosis inhibitor Fer-1 but not by the classic iron chelating agents and ROS scavengers.

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Article Synopsis
  • The study investigates how guanine oxidation occurs when using a technique called flash-quench on double-stranded DNA, revealing important oxidation products.
  • The researchers identified imidazolone dIz and dZ as the main products formed during this process, particularly when Ru(OP)dppz is involved with a quencher called methyl viologen.
  • They noted that the presence of certain chemicals can influence the formation of these products, indicating a new method to explore simultaneous radical generation in DNA oxidation.
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