Publications by authors named "Jeffrey B Jorgensen"

Importance: Studies comparing perioperative outcomes of fibula free flaps (FFFs), osteocutaneous radial forearm free flaps (OCRFFFs), and scapula free flaps (SFFs) have been limited by insufficient sample size.

Objective: To compare the perioperative outcomes of patients who underwent FFFs, OCRFFFs, and SFFs.

Design, Setting, And Participants: This cohort study assessed the outcomes of 1022 patients who underwent FFFs, OCRFFFs, or SFFs for head and neck reconstruction performed at 1 of 6 academic medical centers between January 2005 and December 2019.

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Objectives: (1) Evaluate the association of flap type with late complications in patients undergoing osseous head and neck reconstruction with the fibula free flap (FFF), osteocutaneous radial forearm free flap (OCRFFF), and scapula free flap (SFF). (2) Compare the prevalence of late complications based on minimum duration of follow-up.

Study Design: Retrospective cohort study.

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Background: The association of comorbidities with perioperative outcomes after transoral robotic surgery (TORS) is not well-defined in the literature.

Methods: Using the National Cancer Database, 4004 patients with T1-T2 oropharyngeal cancer between 2010 and 2017 were stratified based on their Charlson-Deyo Comorbidity Class (CDCC). Thirty-day unplanned readmissions, 30-day mortality, and 90-day mortality were compared using chi-square test and logistic regression.

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Objectives/hypothesis: Investigate the relationship between site and pattern of distant metastasis (DM) and overall survival (OS) in a multi-institutional cohort of patients with DM head and neck cancer (HNC).

Study Design: Retrospective review.

Methods: 283 patients treated at 4 academic centers in the Midwest HNC Consortium between 2000 and 2015 were retrospectively reviewed.

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Article Synopsis
  • The study investigates how different treatment methods impact chronic opioid use in patients with head and neck cancer.
  • Among 388 patients, notable opioid use was found, with 43% at 3 months and 33% at 6 months post-treatment.
  • Primary chemoradiation, previous opioid use, and other factors like tobacco use and psychiatric disorders significantly increased the likelihood of chronic opioid use, suggesting targeted preventive strategies for these patients are needed.
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Prophylactic arterial ligation has been proposed to reduce the severity of postoperative hemorrhage following transoral robotic surgery (TORS). Previous studies have shown a trend toward a reduction in major and severe bleeding. Search strategies were implemented in multiple databases and completed in August 2018.

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Background: The effect of treatment modality on long-term opioid dependence in patients with oropharyngeal cancer has not been reported.

Methods: A retrospective cohort of 122 patients with T1/T2 oropharyngeal cancer undergoing treatment was generated. Risk factors associated with chronic opioid use were investigated by univariate and multivariate analyses.

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Objectives: (1) For patients with oral squamous cell carcinoma (OSCC) and mandibular invasion, to determine whether prior radiation to the head and neck region (PXRTHN) affects the density of osteoblasts, osteoclasts, or fibroblasts along the tumor interface invading the mandible and whether this is significantly associated with overall survival. (2) To identify clinicopathologic features that are associated with overall survival.

Study Design: Case series with chart review.

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Liposarcoma of the thyroid gland is a pathology that is rarely encountered in clinical practice, given the paucity of these cases. For the same reason, a definite treatment protocol has not been established for these cases. We present a case of a 49-year-old man who presented with a thyroid mass that was found to be a well-differentiated liposarcoma and was treated surgically with no adjuvant therapy other than close surveillance with clinical examination and MRI scans.

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Objective: To determine if the routine use of intraoperative frozen section (iFS) results in cost savings among patients with nodules >4 cm with nonmalignant cytology undergoing a thyroid lobectomy.

Study Design: Case series with chart review; cost minimization analysis.

Setting: Single academic center.

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Background: The effects of perioperative hyperglycemia on complications and outcomes in microvascular reconstruction have not been reported in the literature.

Methods: A retrospective cohort of 203 patients undergoing microvascular reconstruction was generated. Perioperative glucose levels and clinical factors were tested for associations with complications using simple and multivariate analyses.

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Objective To perform a cost analysis of the routine use of intraoperative frozen section (iFS) among patients undergoing a thyroid lobectomy with "suspicious for malignancy" (SUSP) cytology in the context of the 2015 American Thyroid Association guidelines. Study Design Case series with chart review; cost minimization analysis. Setting Academic.

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Background: Free tissue transfer is a mainstay in reconstruction of complex head and neck defects. The purpose of this study was to determine if perioperative complications were more common in patients with body mass index (BMI) >30 kg/m(2) undergoing free flap reconstruction.

Methods: A multi-institutional retrospective cohort was created.

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Objective: To describe a novel use of fluorescent angiography in assessing donor limb perfusion prior to free tissue harvest in microvascular free tissue transfer.

Study Design: Retrospective case series.

Methods: From January 2012 to June 2013, 59 patients underwent head-and-neck microvascular free tissue reconstruction.

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Objective: Identify and quantify changes in length of the skin incision following minimally invasive thyroid and parathyroid surgery and determine whether these changes persist postoperatively.

Study Design: Cohort study.

Setting: Tertiary care teaching hospital.

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Objective: To evaluate the capability of ultrasound for preoperative localization in primary hyperparathyroidism.

Study Design: Prospective study.

Setting: Multi-institutional Midwest Head and Neck Cancer Consortium.

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