Publications by authors named "Jan-Erik WiSSmann"
Background & Aims: Hepatitis E virus (HEV) is the most common cause of acute viral hepatitis worldwide and is mainly transmitted via the fecal-oral route or through consumption of contaminated food products. Due to the lack of efficient cell culture systems for the propagation of HEV, limited data regarding its sensitivity to chemical disinfectants are available. Consequently, preventive and evidence-based hygienic guidelines on HEV disinfection are lacking.
View Article and Find Full Text PDFFor the prevention of infectious diseases, knowledge about transmission routes is essential. In addition to respiratory, fecal-oral, and sexual transmission, the transfer of pathogens via surfaces plays a vital role for human pathogenic infections-especially nosocomial pathogens. Therefore, information about the survival of pathogens on surfaces can have direct implications on clinical measures, including hygiene guidelines and disinfection strategies.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates the presence and characteristics of hepatitis E virus (HEV) in the ejaculate of infected individuals and pigs, revealing that HEV can persist in the male reproductive system even after viremia has resolved.
- It found HEV levels in semen to be significantly higher than in serum among chronically infected patients, with distinct genetic variants present in different body fluids.
- The research highlights the potential for HEV to spread via the male reproductive tract, contributing to a better understanding of HEV's replication and persistence beyond blood.