Publications by authors named "Jan Robert Kroeger"

Background: Photon counting CT (PCCT) is a promising technique for neuroradiological CT examinations. In initial studies on non-contrast PCCT of the head (NCCT), however, artifacts close to the calvarium were noticed, which lead to an inhomogeneous representation of the brain tissue. In this study, a new software for image reconstruction to reduce artifacts is evaluated.

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The purpose of this study was to evaluate the accuracy and feasibility of magnetic resonance (MR)-guided periradicular nerve root injection therapy (PRT) using a 0.55 T magnetic resonance imaging (MRI) system with fast dynamic imaging in a phantom. Five radiologists with varying levels of experience in PRT performed nine randomly assigned PRT procedures: three under MR guidance, three under CT guidance using a fully integrated laser navigation system, and three under conventional CT guidance, all on a specialized phantom of the lumbar spine.

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PurposeNon-contrast cerebral computed tomography (NCCT) is one of the most frequently performed CT examinations. Photon-counting CT (PCCT) offers advantages in terms of noise reduction, higher spatial resolution, and inherent spectral information. PCCT available today allows NCCT to be performed with tube voltage of 120 or 140 kVp.

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Objectives: To examine photon counting-CT (PCCT)-derived virtual monoenergetic images (VMI) in combination with iterative metal artifacts reduction algorithms (iMAR) for artifact reduction in patients with dental implants (DI).

Methods: 49 patients with DI were retrospectively included in the study. Polyenergetic CT images (CI), VMIs with different energy levels (70-190 keV) without and the same images with iMAR were examined.

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Purpose: Qualitative comparison of image quality and diagnostic usability of the recently introduced ZeeFree (ZF) reconstruction algorithm for photon-counting coronary CT angiography (cCTA) with Standard (SD) and TrueStack (TS) reconstruction algorithms.

Methods And Materials: This retrospective single-center study included 59 patients (mean age 62.5 ± 13.

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Article Synopsis
  • The study evaluates how the quality of computed tomography angiography (CTA) images, particularly those from Photon Counting Computed Tomography (PCCT), impacts the effectiveness of a deep learning (DL) algorithm in detecting large vessel occlusions (LVO) during acute ischemic stroke diagnostics.
  • 443 cases were analyzed, including both positive and negative occlusion cases, and the DL software prototype's performance was assessed with sensitivity and specificity metrics.
  • Results showed that the DL algorithm performed better with PCCT images compared to conventional CT images, achieving higher sensitivity for all occlusions and a marked improvement in identifying M2 occlusions, suggesting that improved image quality enhances detection capabilities but further research is necessary.
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Objectives: Coronary CT angiography (CCTA) is becoming increasingly important in the workup of coronary artery disease. Imaging of stents and in-stent stenoses remains a challenge. This work investigates the assessability of in-stent stenoses in photon counting CT (PCCT) using ultra-high-resolution (UHR) imaging and optimized reconstruction kernels.

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Purpose: To evaluate gyroscope-assisted CT-guided needle puncture (GAP) compared to free hand puncture (FHP) in a phantom.

Material And Methods: A simple, low-cost gyroscope was equipped with a magnetic rail to attach it to common puncture needles. 18 radiologists with different levels of training and experience in CT-guided punctures first punctured three targets in free hand technique in a special biopsy phantom with different difficulty levels of the puncture path (T1: not angulated, needle path 7.

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The purpose of the present study is to evaluate whether an online reference system (ORS, STATdx Elsevier, Amsterdam, Netherlands) impacts finding the histologically confirmed diagnosis of rare or atypical abdominal tumors and lesions in radiologic imaging. In total, 101 patients with rare tumor entities or lesions and atypical manifestations of common tumors were enrolled retrospectively. Blinded readings were performed by four radiologists with varying levels of experience, who reported on: (a) correct diagnosis (CD), (b) time needed to find the diagnosis, and (c) diagnostic confidence, initially without followed by the assistance of the ORS.

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Background: Acute pulmonary embolism (APE) is a potentially life-threatening disorder, emphasizing the importance of accurate risk stratification and survival prognosis. The exploration of imaging biomarkers that can reflect patient survival holds the potential to further enhance the stratification of APE patients, enabling personalized treatment and early intervention. Therefore, in this study, we develop computed tomography pulmonary angiography (CTPA) radiomic signatures for the prognosis of 7- and 30-day all-cause mortality in patients with APE.

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Background Coronary artery calcium scoring (CACS) for coronary artery disease requires true noncontrast (TNC) CT alongside contrast-enhanced coronary CT angiography (CCTA). Photon-counting CT provides an algorithm (PureCalcium) for reconstructing virtual noncontrast images from CCTA specifically for CACS. Purpose To assess CACS differences based on PureCalcium images derived from contrast-enhanced photon-counting CCTA compared with TNC images and evaluate the impact of these differences on the clinically relevant classification of patients into plaque burden groups.

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Rationale And Objectives: Coronary computed tomography angiography (CCTA) is becoming increasingly important for the diagnostic workup of coronary artery disease, nevertheless, imaging of in-stent stenosis remains challenging. For the first time, spectral imaging in Ultra High Resolution (UHR) is now possible in clinically available photon counting CT. The aim of this work is to determine the optimal virtual monoenergetic image (VMI) for imaging in-stent stenoses in cardiac stents.

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Objectives: Glioses appear as hypodense lesions in non-contrast CT examinations of the head. Photon counting CT (PCCT) enables the calculation of virtual monoenergetic images (VMI). The aim of this study is to investigate in which VMI hypodense gliotic lesions can be delineated best.

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Purpose Of The Study: The aim of the study was to identify differences in the tumor conspicuity of pancreatic adenocarcinomas in different monoenergetic or polyenergetic reconstructions and contrast phases in photon-counting CT (PCCT).

Material And Methods: 34 patients were retrospectively enrolled in this study. Quantitative image analysis was performed with region of interest (ROI) measurements in different monoenergetic levels ranging from 40 up to 70 keV (5-point steps) and polyenergetic series.

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Purpose: To determine the optimal virtual monoenergetic image (VMI) for detecting and assessing intracranial hemorrhage in unenhanced photon counting CT of the head based on the evaluation of quantitative and qualitative image quality parameters.

Methods: Sixty-three patients with acute intracranial hemorrhage and unenhanced CT of the head were retrospectively included. In these patients, 35 intraparenchymal, 39 intraventricular, 30 subarachnoidal, and 43 subdural hemorrhages were selected.

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Rationale And Objectives: Accurate and efficient estimation of patient height and weight is crucial to ensure patient safety and optimize the quality of magnetic resonance imaging (MRI) procedures. Several height and weight estimation methods have been proposed for use in adult patient management, but none is widely established. Estimation by the medical technologists for radiology (MTR) based on personal experience remains to be the most common method.

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The purpose of the present study was to evaluate the subjectively perceived patient comfort during magnetic resonance imaging (MRI) examinations and to assess potential differences between a recently introduced low field MRI scanner and a standard MRI scanner. Among other characteristics, the low field MRI scanner differs from the standard MRI scanner by offering more space (wider bore size of 80 centimeter diameter) and producing less noise, which may influence the patient comfort. In total, 177 patients were surveyed after MRI scans with either the low field MRI scanner (n = 91, MAGNETOM Free.

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Background: Sarcopenia is proposed as a novel imaging biomarker in several acute conditions regarding outcome and mortality. The aim of the present study was to investigate the prognostic role of the masseter muscles in patients with acute ischemic stroke (AIS).

Methods: Overall, 189 patients with AIS that received mechanical thrombectomy were retrospectively enrolled in this study.

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Purpose: Purpose of this study is to re-evaluate the accuracy and diagnostic reliability of virtual non-contrast (VNC) images acquired with the photon-counting computed tomography (PCCT) after an update of the CT scanner software.

Methods: Fifty-four patients were retrospectively enrolled. VNC images were reconstructed from true non-contrast (TNC) images (VNCn) and contrast-enhanced images in portal venous contrast phase (VNCv).

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Purpose: Nonenhanced computed tomography (CT) of the head is among the most commonly performed CT examinations. The spectral information acquired by photon counting CT (PCCT) allows generation of virtual monoenergetic images (VMI). At the same time, image noise can be reduced using quantum iterative reconstruction (QIR).

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Purpose: Imaging stents and in-stent stenosis remains a challenge in coronary computed tomography angiography (CCTA). In comparison to conventional Computed Tomography, Photon Counting CT (PCCT) provides decisive clinical advantages, among other things by providing low dose ultra-high resolution imaging of coronary arteries. This work investigates the image quality in CCTA using clinically established kernels and those optimized for the imaging of cardiac stents in PCCT, both for in-vitro stent imaging in 400 μm standard resolution mode (SRM) and 200 μm Ultra High Resolution Mode (UHR).

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Rationale And Objectives: To evaluate the potential to reduce the amount of iodinated contrast media (CM) for computer tomographic pulmonary angiography (CTPA) with a novel photon-counting-detector CT (PCCT).

Materials And Methods: Overall, 105 patients referred for CTPA were retrospectively included in this study. CTPA was performed using bolus tracking and high-pitch dual-source scanning (FLASH mode) on a novel PCCT (Naeotom Alpha, Siemens Healthineers).

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Objectives: Low-field MRI at 0.55 Tesla (T) with deep learning image reconstruction has recently become commercially available. The objective of this study was to evaluate the image quality and diagnostic reliability of knee MRI performed at 0.

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The AI-Rad Companion Chest X-ray (AI-Rad, Siemens Healthineers) is an artificial-intelligence based application for the analysis of chest X-rays. The purpose of the present study is to evaluate the performance of the AI-Rad. In total, 499 radiographs were retrospectively included.

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This study evaluated the feasibility of reducing the radiation dose in abdominal imaging of urolithiasis with a clinical photon-counting CT (PCCT) by gradually lowering the image quality level (IQL) without compromising the image quality and diagnostic value. Ninety-eight PCCT examinations using either IQL70 (n = 31), IQL60 (n = 31) or IQL50 (n = 36) were retrospectively included. Parameters for the radiation dose and the quantitative image quality were analyzed.

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