Front Public Health
August 2025
Concerns about the impacts on the public health and safety of radiofrequency (RF) exposure are increasing with the rapid proliferation of cellular mobile telecommunication systems and devices. There is also lack of confidence surrounding the applicability of stated health safety rules, limits and guidelines for RF exposure including their use for 5G and the expected 6G. This paper: (1) considers the currently promulgated standards for safe human exposure to RF radiation, (2) examines assumptions underlying the standards, (3) describes the roles of the military industrial complex in influencing research on the health effects and standards setting for safety levels, (4) discusses the engagement of an industry-regulatory complex, (5) explains the interaction between ICNIRP and the WHO-EMF, (6) scrutinizes recent publications of WHO-EMF commissioned systematic reviews, and (7) concludes with some observations on an apparent paradigm shift.
View Article and Find Full Text PDFAm J Cancer Res
June 2025
Whether the aldehyde dehydrogenase 2 (ALDH2) rs671 polymorphism predicts clinical prognosis in alcoholic liver disease (ALD)-related hepatocellular carcinoma (HCC) after hepatectomy remains unclear. Hence, this study aims to investigate the association between ALDH2 rs671 polymorphism and HCC recurrence and mortality in patients with ALD-related HCC who underwent hepatectomy. We also explored the risk factors for HCC recurrence and mortality in this population of patients.
View Article and Find Full Text PDFAberrant NLRP3 (NACHT-, leucine-rich repeat [LRR]- and pyrin domain [PYD]- containing protein 3) inflammasome activation is linked to many inflammatory diseases, driving the search for therapeutics inhibiting this pathway. NEK7 is proposed to mediate NLRP3 inflammasome assembly and activation by bridging adjacent NLRP3 subunits. Hence, reduction of NEK7 protein may block NLRP3 activation.
View Article and Find Full Text PDFBallistic fractures of the wrist and forearm warrant special consideration due to the proximity of neurovascular structures. Each case requires a thorough assessment for concomitant peripheral nerve and vascular injury as well as the presence of possible development of compartment syndrome, which may be difficult to detect in the setting of the multiply injured patient. The extent of bony and soft tissue injury with the degree of contamination present should be factored into decisions regarding antibiotic treatment and surgical debridement, and the strategy for fracture stabilization and management of osseous defects should be tailored to the individual.
View Article and Find Full Text PDFJ Hand Surg Glob Online
July 2025
Purpose: Although poor glycemic control has been shown to be a risk factor for surgical site infection (SSI) for many elective musculoskeletal procedures, this association in the setting of carpal tunnel release (CTR) is unclear in the existing literature.
Methods: A chart review was performed on 1,000 consecutive patients who underwent elective endoscopic or open CTR. Patient characteristics such as diabetic status, insulin dependence, HbA1c levels within 6 months of surgery, perioperative antibiotics, and diagnosis of SSI were obtained from the electronic medical record.
Objective: The epidemiological distribution of patients with brachial plexus injury (BPI) has not been well described. We categorized new consultations at our specialty clinic, aiming to offer insights into demographics and presentations to guide those considering establishing brachial plexus clinics in understanding the types of patients they may encounter.
Methods: All new consultations seen at a single quaternary center's brachial plexus clinic were reviewed over a 10-year period.
Am J Ophthalmol
September 2025
Purpose: To determine the utility of cytomegalovirus retinitis (CMVR) screening among patients with cytomegalovirus (CMV) bloodstream infection (viremia) in the context of multiple and recently implemented statewide policies in heightening congenital screening.
Design: Retrospective diagnostic testing evaluation.
Subjects: All patients with CMV viremia and ophthalmologic examination during the study period between 2010 and 2023 were included.
IEEE Trans Med Imaging
August 2025
Preterm neonates are vulnerable to periventricular-intraventricular hemorrhage since the periventricular germinal matrix blood vessels are still immature and fragile until around 36 weeks. While cranial ultrasound imaging (cUS) is the standard technique for diagnosing brain injury in neonates, it has limited accuracy in detecting early-stage hemorrhages due to poor sensitivity and specificity. Transfontanelle thermoacoustic imaging (TTAI) combines the advantages of high contrast from electromagnetic absorption with high-resolution from ultrasound imaging and represents a potential alternative to overcome the limitations of conventional cUS systems.
View Article and Find Full Text PDFGrapevine is an important commercial crop widely grown in the world. However, grapevine cultivation has long been seriously threatened by grapevine downy mildew caused by Plasmopara viticola. Screening the resistance resources and identifying the resistance germplasm is the key to improve the resistance of cultivars to P.
View Article and Find Full Text PDFMicrowave-induced thermoacoustic tomography (TAT) is a hybrid imaging technique that combines microwave excitation with ultrasound detection to create detailed images of biological tissue. Most TAT systems require a costly amplification system (or a sophisticated high-power microwave source), which limits the wide adoption of this imaging modality. We have developed a rotating single-element thermoacoustic tomography (RTAT) system using a low-cost amplifier that has been optimized in terms of microwave signal pulse width and antenna placement.
View Article and Find Full Text PDFSystematic exploration of the hadal zone, Earth's deepest oceanic realm, has historically faced technical limitations. Here, we collected 1,648 sediment samples at 6-11 km in the Mariana Trench, Yap Trench, and Philippine Basin for the Mariana Trench Environment and Ecology Research (MEER) project. Metagenomic and 16S rRNA gene amplicon sequencing generated the 92-Tbp MEER dataset, comprising 7,564 species (89.
View Article and Find Full Text PDFIntroduction: Demarcation laser photocoagulation (DLP) is an infrequently utilized modality for limited retinal detachments. The current study, a retrospective consecutive case series, reviewed anatomic and visual outcomes in these patients at a single academic center.
Case Presentations: A search of the electronic medical record identified 10 eyes of 10 patients.
Nat Chem Biol
August 2025
Sodium influx and overload are frequently observed in human tissue injuries. Whether sodium overload imposes a causative effect on necrotic cell death and the mechanism involved are unclear. Here we identify necrocide 1 (NC1) as a compound that induces necrotic cell death through sodium overload, termed NECSO for necrosis by sodium overload.
View Article and Find Full Text PDFJ Tradit Complement Med
November 2024
Objective: This study was designed to determine the efficacy and safety of electroacupuncture (EA) at acupoints ST36 and/or PC6 for postoperative gastrointestinal (GI) recovery.
Method: Studies were retrieved from the PubMed, EMBASE, China National Knowledge Infrastructure (CNKI), Wanfang, and Airiti library databases from inception to January 23, 2024. Randomized controlled trials (RCTs) that evaluated the effect of EA at ST36 and/or PC6 on postoperative GI recovery were reviewed.
Cases: Two patients with spontaneous loss of thumb interphalangeal joint extension were referred after history, electrodiagnostic, and/or magnetic resonance imaging (MRI) findings were felt to demonstrate a posterior interosseous nerve (PIN) palsy. Subsequent physical examination and additional directed studies suggested an alternative explanation: rupture of the extensor pollicis longus (EPL) tendon, subsequently confirmed at surgery. An extensor indicis proprius to EPL transfer restored thumb function.
View Article and Find Full Text PDFAngew Chem Int Ed Engl
January 2025
We report the development of a small molecule-based barcoding platform for pooled screening of nanoparticle delivery. Using aryl halide-based tags (halocodes), we achieve high-sensitivity detection via gas chromatography coupled with mass spectrometry or electron capture. This enables barcoding and tracking of nanoparticles with minimal halocode concentrations and without altering their physicochemical properties.
View Article and Find Full Text PDFTo describe the ophthalmic outcomes and complications after silicone oil (SO) removal. This nonrandomized retrospective review comprised patients who had SO removal from January 2020 to December 2022. Data collected included patient demographics, visual acuity (VA), intraocular pressure (IOP), initial tamponade, indication for SO placement, duration of SO in the eye, indication for SO removal, cataract progression, rates of retinal redetachment, cornea-related complications, additional surgical interventions, and other complications.
View Article and Find Full Text PDFImportance: Oral anticoagulation for adults with atrial fibrillation or atrial flutter (AFF) who are at elevated stroke risk reduces the incidence of ischemic stroke but remains underused. Efforts to increase anticoagulation initiation on emergency department (ED) discharge have yielded conflicting results.
Objective: To evaluate the effectiveness of a multipronged intervention supporting anticoagulation initiation for eligible adult ED patients.
We report the development of a small molecule-based barcoding platform for pooled screening of nanoparticle delivery. Using aryl halide-based tags (halocodes), we achieve high-sensitivity detection via gas chromatography coupled with mass spectrometry or electron capture. This enables barcoding and tracking of nanoparticles with minimal halocode concentrations and without altering their physicochemical properties.
View Article and Find Full Text PDFDistal radioulnar joint instability is commonly seen after surgical fixation of a distal radial fracture, and surgeons' ability to reliably determine stability on examination is poor. Debate remains regarding whether to fix the ulnar styloid or reinsert the triangular fibrocartilaginous complex. Four surgeons with Level 5 expertise were asked to respond to questions surrounding this debate.
View Article and Find Full Text PDFDegenerative wrist conditions, such as scapholunate advanced collapse and scaphoid nonunion advanced collapse, often require salvage procedures to reduce pain and improve function. For early stages of disease, both proximal row carpectomy and scaphoid excision four-corner arthrodesis are viable motion-preserving options. There remains controversy on which technique is superior.
View Article and Find Full Text PDFObjective: To develop and validate tools for measuring inpatient gastroenterology (GI) consultation quality on oncologic patients.
Methods: A total of 145 inpatient GI consults were analyzed using electronic health records in this cross-sectional study. Essential Consult Elements on oncologic-hospitalized patients (EE-COH) and Hospitalized Oncologic Patients Enhanced Quality of Consult Assessment Tool (HOPE-QCAT) were used for grading.