Cardiac tamponade is a rare, life-threatening condition caused by accumulation of pericardial fluid, leading to rapid changes in hemodynamic status. Common causes include cancer, chest trauma, pericarditis, autoimmune diseases, and infectious agents such as viruses, bacteria, and fungi. Patients typically present with symptoms of weakness, chest pain, and shortness of breath.
View Article and Find Full Text PDFCase Rep Cardiol
May 2025
Despite advances in imaging and diagnostics, calcific constrictive pericarditis (CCP) remains a rare and challenging entity, often masquerading as other cardiopulmonary conditions, leading to delayed diagnosis. We present a 70-year-old male with a history of heart failure, atrial fibrillation (AF), cirrhosis, chronic obstructive pulmonary disease (COPD), and prior pleural effusion, who was admitted with acute hypoxic respiratory failure and AF with rapid ventricular response (RVR). Imaging revealed extensive pericardial calcifications, leading to a diagnosis of CCP.
View Article and Find Full Text PDFIn recent years, there has been a significant reduction in the use of warfarin, as many patients have transitioned to direct oral anticoagulants (DOACs) for the management of atrial fibrillation. However, a considerable number of patients continue to rely on warfarin due to financial limitations and the specific requirement for its use in individuals with mechanical heart valves, given the insufficient data on the effectiveness of DOACs in these scenarios. While warfarin is recognized for its high efficacy, it possesses a narrow therapeutic window, necessitating careful monitoring to avoid excessive bleeding.
View Article and Find Full Text PDFSpine (Phila Pa 1976)
December 2024
Study Design: This was an observational study.
Objective: This study aims to explore sociodemographic and regional geographic variations in lower back pain (LBP) incidence, prevalence, and burden in the United States (US from 2000 to 2019).
Summary Of Background Data: LBP is a major contributor to lost wages and disability in the United States.
Background: Guidelines and risk scores have sought to standardize the management of syncope in the emergency department (ED), but variation in practice remains.
Objective: The purpose of this study was to explore factors associated with admission for patients presenting to the ED with low-risk syncope.
Methods: Our study population included adult patients in the Nationwide Emergency Department Sample between 2006 and 2019 who presented to an ED with a primary diagnosis of syncope.
With the incidence of central and peripheral nervous system disorders on the rise, neurosurgical procedures paired with the careful administration of select medications have become necessary to optimize patient outcomes. Despite efforts to decrease the over-prescription of common addictive drugs, such as opioids, prescription costs continue to rise. This study analyzed temporal trends in medication use and cost for spinal fusion and brain tumor resection procedures.
View Article and Find Full Text PDFAcute pancreatitis (AP) is a common medical condition with a wide variety of etiologies. One of the common but frequently undetected causes of acute pancreatitis is microlithiasis, which can appear as biliary "sludge" in the gallbladder on imaging. While a broad workup should be initiated, endoscopic retrograde cholangiopancreatography (ERCP) is the gold standard for the diagnosis of microlithiasis.
View Article and Find Full Text PDFBackground: Vitamin D deficiency and altered body composition are common in Alzheimer's disease (AD). Memantine with vitamin D supplementation can protect cortical axons against amyloid-β exposure and glutamate toxicity.
Objective: To study the effects of vitamin D deprivation and subsequent treatment with memantine and vitamin D enrichment on whole-body composition using a mouse model of AD.