Publications by authors named "Jae Eun Seong"
Background: Antimicrobial resistance is an emergent threat, with Carbapenemase-Producing Enterobacterales (CPE) and Vancomycin-Resistant Enterococcus (VRE) posing substantial challenges. We investigated CPE/VRE acquisition and spread in hospitalized patients by analysing resistance genes and microbiomes using whole genome sequencing (WGS) and exploring epidemiological and clinical risk factors.
Methods: This retrospective study included patients from the infectious disease department of a tertiary hospital.
Article Synopsis
- Severe fever with thrombocytopenia syndrome (SFTS) is caused by the SFTS virus (SFTSV) and is transmitted by ticks.
- CP-COV03 is a new antiviral drug that improves the availability of niclosamide, which has shown effectiveness against over 30 viruses in testing.
- The study tested CP-COV03 on SFTSV-infected Vero cells and found that it significantly reduced viral effects, suggesting it could be a promising treatment for SFTS.
Epidemiological and Clinical Characteristics of Women Living with HIV in Korea.
Infect Chemother
September 2024
Article Synopsis
- Korea is experiencing a steady increase in newly diagnosed HIV cases, with women living with HIV making up 6.4% of the population, yet research on this group is limited.
- A study analyzed data from 443 women living with HIV, identifying heterosexual contact as the primary risk factor, with 91.2% receiving antiretroviral therapy.
- Findings showed significant health outcomes, including 118 pregnancies and various health issues such as breast and cervical cancer, indicating the need for focused health strategies for women with HIV in Korea.
Article Synopsis
- A study in South Korea assessed the effectiveness of the XBB.1.5 COVID-19 vaccine against symptomatic infections, hospitalizations, and the need for oxygen therapy during late 2023.
- A total of 5,516 subjects were analyzed, revealing that the vaccine had absolute effectiveness rates of 65.2% for COVID-19 infection, 77.3% for hospitalization, and 85.3% for oxygen therapy, compared to unvaccinated individuals.
- The results suggest significant short-term effectiveness of the XBB.1.5 vaccine, but further long-term studies are needed to monitor ongoing effectiveness.
With advancements in antiretroviral therapy (ART), the average lifespan of people with human immunodeficiency virus (HIV) is increasing, as is the number of older adults with HIV. Accordingly, the number of patients with HIV who undergo surgery or require critical care for various reasons is increasing. Since the prognosis of people with HIV depends on the continuous and effective maintenance of ART, there is a need to consider effectively maintaining ART in people with HIV in these conditions.
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