Congress of Neurological Surgeons Systematic Review and Evidence-Based Guidelines for the Role of Imaging for Patients With Functioning Pituitary Adenomas.

Background: Patients with functioning pituitary adenomas (FPA) present a diagnostic challenge with identification of microadenomas and/or invasion of the cavernous sinus.

Objective: The aim of this study was to provide evidence-based recommendations on the use of imaging to facilitate an accurate diagnosis.

Methods: PubMed and Embase were searched from the inception of the database to June 8, 2021, using search terms and search strategies to identify pertinent abstracts.

Congress of Neurological Surgeons Systematic Review and Evidence-Based Guidelines for the Role of Surgery for Patients With Functioning Pituitary Adenomas.

Background And Objectives: With the recent improvements in surgery, along with our ability to manage many pituitary tumors medically, the exact role of surgery for the treatment of functioning pituitary adenomas (PA) remains unclear. The purpose of this evidence-based clinical practice guideline was to determine the role of surgery in the treatment of functioning PA.

Methods: A systematic review of the literature was performed using the National Library of Medicine/PubMed database and Embase for studies relevant to the role of surgery in the treatment of patients with functioning PA.

Congress of Neurological Surgeons Systematic Review and Evidence-Based Guidelines for the Role of Radiosurgery for Patients With Functioning Pituitary Adenomas.

Background: Patients with functioning pituitary adenomas (FPA) require a multidisciplinary team-based approach to select best medical, surgical, and radiation treatments, including stereotactic radiosurgery (SRS).

Objective: The aim of this study was to provide evidence-based recommendations on the use of SRS for adult patients with FPA.

Methods: PubMed and Embase were searched from data base inception to June 8, 2021.

Congress of Neurological Surgeons Systematic Review and Evidence-Based Guidelines for the Role of Medical Perioperative Management for Patients With Functioning Pituitary Adenomas.

Background And Objectives: Standardized perioperative management of patients with functioning pituitary adenomas is important for optimal medical and surgical outcomes. Review of the literature to evaluate the impacts of (1) postoperative fluid restriction and sodium level checks to prevent delayed hyponatremia and hospital-related readmissions, (2) preoperative somatostatin analog (SSA) medical treatment in patients with growth hormone-secreting tumors and its effects on surgical and medical outcomes, and (3) immediate postoperative pituitary hormone testing in patients with adrenocorticotropic hormone (ACTH)-secreting tumors to predict adrenal insufficiency and disease remission.

Methods: Systematic literature search using Embase and PubMed from 1946 to June 2021.

Congress of Neurological Surgeons Systematic Review and Evidence-Based Guideline on the Role of Radiosurgery (Stereotactic Radiosurgery) and Radiation Therapy in the Management of Patients With Vestibular Schwannomas: Updates.

Background: Stereotactic radiosurgery (SRS) is an established modality for treatment of adult patients with vestibular schwannomas (VS). The aim of this work was to provide an updated literature review on this topic.

Objective: To review the literature published since the last guideline on this topic.

The Evolving Landscape of Radiomics in Gliomas: Insights into Diagnosis, Prognosis, and Research Trends.

Gliomas are the most prevalent and aggressive form of primary brain tumors. The clinical challenge in managing patients with this disease revolves around the difficulty of diagnosis, both at onset and during treatment, and the scarcity of prognostic outcome indicators. Radiomics involves the extraction of quantitative features from medical images with the help of artificial intelligence, positioning it as a promising tool to be integrated into the care of glioma patients.

Enhanced Recovery After Adult Brain Tumor Surgery: A Proposed Succinct Evidence-Based Protocol.

Background And Objectives: Enhanced recovery after surgery (ERAS) for brain tumor surgery holds promise for improving outcomes. However, its lack of standardization has led to financial and logistic barriers, hindering its widespread adoption and optimization. This study seeks to identify ERAS variables across the preoperative, intraoperative, and postoperative phases associated with shorter hospital length of stay (LOS), decreased postoperative pain, and reduced costs.

Navigating the Crossroads: A 10-Year Population Study on Access to Care Among Patients With Brain Tumor.

Background And Objectives: Health care disparities are introduced at various points along the patient care continuum. This study explores disparities in initial health care access for patients with brain tumor (BT) in New York City (NYC) and New York State (NYS), comparing emergency department (ED) and elective admissions (EA).

Methods: Using 2010-2020 data from the Statewide Planning and Research Cooperative System of NYS, patients were identified through relevant billing codes.

Transforming Brain Tumor Care: The Global Impact of Radiosurgery in Multidisciplinary Treatment Over Two Decades.

Background: Stereotactic radiosurgery, a minimally invasive treatment delivering high doses of radiation to a well-defined target, has transformed interdisciplinary treatment paradigms since its inception. This study chronicles its adoption and evolution for brain cancer and tumors globally.

Methods: A systematic literature review of SRS-focused articles from 2000 to 2023 was conducted.

Molecular profile and clinical outcome of adult primary spinal cord glioblastoma: a systematic review.

Objective: Primary spinal cord glioblastoma (scGB) is a rare and aggressive spinal glioma, making up 7.5% of such cases. Whereas molecular profiles associated with improved overall survival (OS) are well studied for cranial glioblastoma (GB), the molecular characteristics of scGB are less documented.

Charting the success of neuronavigation in brain tumor surgery: from inception to adoption and evolution.

Purpose: Neuronavigation, explored as an intra-operative adjunct for brain tumor surgery three decades ago, has become globally utilized with a promising upward trajectory. This study aims to chart its success from idea to adoption and evolution within the US and globally.

Methods: A three-pronged methodology included a systematic literature search, impact analysis using NIH relative citation ratio (RCR) and Altmetric scores, and assessment of patent holdings.

American Association of Neurological Surgeons/Congress of the Neurological Surgeons Section on Tumors Guidelines: Assessing Their Impact on Brain Tumor Clinical Practice.

Clinical guidelines direct healthcare professionals toward evidence-based practices. Evaluating guideline impact can elucidate information penetration, relevance, effectiveness, and alignment with evolving medical knowledge and technological advancements. As the American Association of Neurological Surgeons/Congress of Neurological Surgeons Section on Tumors marks its 40th anniversary in 2024, this article reflects on the tumor guidelines established by the Section over the past decade and explores their impact on other publications, patents, and information dissemination.

Simplifying synthesis of the expanding glioblastoma literature: a topic modeling approach.

Purpose: Our study aims to discover the leading topics within glioblastoma (GB) research, and to examine if these topics have "hot" or "cold" trends. Additionally, we aim to showcase the potential of natural language processing (NLP) in facilitating research syntheses, offering an efficient strategy to dissect the landscape of academic literature in the realm of GB research.

Methods: The Scopus database was queried using "glioblastoma" as the search term, in the "TITLE" and "KEY" fields.

What is the cognitive footprint of insular glioma?

Cognitive impairment has a profound deleterious impact on long-term outcomes of glioma surgery. The human insula, a deep cortical structure covered by the operculum, plays a role in a wide range of cognitive functions including interceptive thoughts and salience processing. Both low-grade (LGG) and high-grade gliomas (HGG) involve the insula, representing up to 25% of LGG and 10% of HGG.

The intersection of race and social determinants of health on clinical outcome of glioblastoma patients.

Objective: Resection, chemotherapy, radiation therapy, and tumor treating fields significantly increase the overall survival (OS) of glioblastoma (GBM) patients. Yet, cost and healthcare disparities might limit access. Multiple studies have attributed more than 80% of the GBM disease burden to White patients.

Adult neuro-oncology trials in the United States over 5 decades: Analysis of trials completion rate to guide the path forward.

Background: Clinical trials are important to close the gap between therapeutic unmet needs and scientific advances in neuro-oncology. This study analyzes the landscape of neuro-oncology trials to identify completion rates and guide strategies for the path forward.

Methods: US-registered adult neuro-oncology clinical trials were extracted from www.

The Current Landscape of Neurosurgical Oncology in Low-Middle-Income Countries (LMIC): Strategies for the Path Forward.

Objective: To promote global equity in research, innovation, and care, sharing knowledge and grasping current benchmarks is crucial. Despite LIC/LMIC constituting around 80% of the global population, their contribution to neurosurgery research is less than 5%. This study aims to assess the status of neurosurgical oncology in LIC/LMIC using published data, offering strategic insights for progress.

The role of minimally invasive surgery within a multidisciplinary approach for patients with metastatic spine disease over a decade: A systematic review.

Background: Metastatic spine disease (MSD) occurs commonly in cancer patients causing pain, spinal instability, devastating neurological compromise, and decreased quality of life. Oncological patients are often medically complex and frail, precluding them form invasive procedures. To address this issue, minimally invasive spinal surgery (MISS) techniques are desirable.