Publications by authors named "Ikemsinachi C Nzenwa"

Background: The quantitative effect of frailty on post-operative complications in older adults undergoing surgical emergencies is not well understood.

Methods: The 2013-2019ACS-NSQIP database was used to identify emergency laparotomy patients≥65 years. Frailty was measured using the modified-frailty-index-5 factors (mFI-5).

View Article and Find Full Text PDF

Introduction: The Desirability of Outcome Ranking (DOOR) ranks multiple postoperative outcomes, potentially enhancing detection of risks influenced by social determinants of health. We examined the relationship between race, ethnicity, and DOOR scores in pediatric surgical patients.

Methods: Using NSQIP-Pediatric 2012-2022, we identified patients (≤18 years) who underwent general, urological, and gynecological surgery.

View Article and Find Full Text PDF

Introduction: The selection of patients for Extracorporeal Membrane Oxygenation (ECMO) needs to be optimized, especially in patients with severe traumatic brain injury (TBI). We aimed to identify predictors of survival in severe TBI patients. We also characterized trends of ECMO use in patients with severe TBI.

View Article and Find Full Text PDF

Background: Firearm violence is the leading cause of death among US children and adolescents, and school nurses are increasingly recognized as key partners in prevention efforts. While school nurses are uniquely positioned to counsel on firearm safety, existing training curricula often lack content tailored to their specific roles and settings.

Methods: We adapted a hospital-based curriculum for school nurses, comprising a didactic session on firearm violence, secure storage, and counseling frameworks, followed by standardized patient simulations.

View Article and Find Full Text PDF

Background: Fragmentation of Care (FOC) is defined as re-admission to a non-index hospital and may be associated with worse outcomes among Emergency General Surgery (EGS) patients. This study assesses hospital characteristics associated with patterns of FOC in EGS patients and the effect of interfacility transfer after FOC on mortality.

Methods: Using the Nationwide Readmissions Database 2019, we included patients ≥ 18 years old who were admitted to an index hospital with an EGS diagnosis managed operatively, and had an emergency readmission within 90 days.

View Article and Find Full Text PDF

This study examined school nurses' experiences and beliefs about firearm violence and related policies. A cross-sectional survey was conducted at the National Association of School Nurses Annual Conference in July 2023, gathering data on attitudes and knowledge regarding firearm violence prevention. Of the 363 respondents (65% response rate), 98% were female, and 44.

View Article and Find Full Text PDF

Background: The identification of the optimal management for blunt splenic trauma-angioembolization (AE), splenectomy, or observation-remains a challenge. This study applies Optimal Policy Trees (OPT), an artificial intelligence (AI) model, to prescribe appropriate management and improve in-hospital mortality.

Methods: OPTs were trained on patients with blunt splenic injuries in the ACS-TQIP 2013-2019 to prescribe one of the three interventions: splenectomy, angioembolization (AE), or observation.

View Article and Find Full Text PDF

Background: Pulmonary contusion (PC) is considered a relative contraindication to surgical stabilization of rib fractures (SSRF). This study compared outcomes in patients undergoing SSRF vs. non-operative management (NOM).

View Article and Find Full Text PDF

Background: Emergency resuscitative thoracotomy survival rates range widely depending on the mechanism of injury and signs of life at presentation. Given ongoing shortages of blood products, we sought to examine blood product use across this patient population and corresponding survival.

Methods: We identified patients in the American College of Surgeons-Trauma Quality and Improvement Program (2017-2019) undergoing an emergency resuscitative thoracotomy within 30 minutes of hospital arrival.

View Article and Find Full Text PDF

Background: Emergency colorectal surgery has a high incidence of postdischarge complications, and loss to follow-up can delay the identification of complications. Amid evolving postdischarge care practices, it is important to assess predictors of loss to follow-up. We aimed to characterize the predictors of loss to follow-up.

View Article and Find Full Text PDF

Objective: To examine the impact of hospital volume on mortality and healthcare utilization in patients admitted with necrotizing pancreatitis (NP).

Background: Over 20% of patients with acute pancreatitis develop NP, which has been associated with higher rates of procedural intervention, morbidity, and mortality.

Methods: Adult patients admitted with NP were identified in the 2016-2019 Nationwide Readmissions Database 2016-2019.

View Article and Find Full Text PDF

Purpose: This study aims to identify predictors of discharge to post-acute care in geriatric emergency general surgery (EGS) patients.

Methods: This is a retrospective study of geriatric emergency general surgery (EGS) patients at a tertiary care facility between 2017 and 2018. Inclusion criteria were ≥ 65 years old and presented directly from home.

View Article and Find Full Text PDF

Background: Intraoperative adverse events (iAEs) during general surgery can lead to significant morbidity and healthcare burden, yet their impact remains underexplored. We aimed to estimate the nationwide incidence of iAEs in general surgery and explore their associations with mortality, complications, length of stay, and costs.

Methods: We conducted a retrospective cohort study using the Nationwide Readmissions Database 2019 and included adult patients (aged 18 years and older) who underwent general surgical procedures.

View Article and Find Full Text PDF

Background: The prolonged use of percutaneous cholecystostomy tubes (PCTs) in patients with acute cholecystitis, deemed inoperable, is fraught with complications. Transpapillary cholecystoduodenal stenting (TCDS) is an alternative technique that restores the physiologic outflow of bile, avoiding the need for an external drain. However, the long-term safety and efficacy of this approach remain unclear.

View Article and Find Full Text PDF
Article Synopsis
  • Renal angioembolization (RAE) is effective for low-grade renal injuries and may improve outcomes in high-grade renal trauma (HGRT), compared to traditional surgery.
  • A study using data from 591 patients with HGRT found that RAE did not significantly change morbidity or length of hospital stays but was linked to lower mortality rates compared to surgery.
  • The findings suggest that RAE might help preserve kidney function and enhance non-operative treatment efficacy, but further randomized studies are necessary to confirm these results.
View Article and Find Full Text PDF

Introduction: Racial and ethnic disparities in emergency general surgery (EGS) patients have been well described in the literature. Nonetheless, the burden of these disparities, specifically within the more vulnerable older adult population, is relatively unknown. This study aims to investigate racial and ethnic disparities in clinical outcomes among older adult patients undergoing EGS.

View Article and Find Full Text PDF

Purpose: Our understanding of the growing geriatric population's risk factors for outcomes after traumatic injury remains incomplete. This study aims to compare outcomes of severe isolated blunt chest trauma between young and geriatric patients and assess predictors of mortality.

Methods: The ACS-TQIP 2017-2020 database was used to identify patients with severe isolated blunt chest trauma.

View Article and Find Full Text PDF
Article Synopsis
  • Emergent surgical conditions in older patients often require major procedures, making it essential to assess risk factors for better decision-making and care planning.
  • A study analyzing data from thousands of patients aged 65 and older found that 13.6% died within 30 days post-surgery, with ASA status 5, septic shock, and dialysis being significant predictors of mortality.
  • The findings highlight that older patients with these risk factors face extremely high mortality rates after surgery, underscoring the importance of evaluating surgical futility in this vulnerable group.
View Article and Find Full Text PDF
Article Synopsis
  • Obesity is a growing issue, particularly in emergency general surgery (EGS), where its effects on postoperative outcomes and decision-making are not fully understood.
  • Analyzed data from nearly 79,000 EGS patients revealed that higher obesity classes, especially class III, increased risks for postoperative complications, prolonged surgeries, and longer hospital stays.
  • The study indicates a clear link between obesity class and various surgical outcomes, highlighting the need for further research on how BMI influences surgical strategies and costs.
View Article and Find Full Text PDF
Article Synopsis
  • Delayed fascial closure (DFC) is a technique used in emergency general surgery, but its benefits are not well established, prompting a comparison with immediate fascial closure (IFC) for patients with intra-abdominal contamination.
  • A study using data from the American College of Surgeons analyzed outcomes of 36,974 patients undergoing exploratory laparotomy, revealing that DFC leads to higher mortality rates and complications, including pneumonia and longer hospital stays.
  • The findings suggest that while DFC is common, it may lead to worse clinical outcomes and does not reduce complications, indicating a need for more research to clarify when DFC should be used in practice.*
View Article and Find Full Text PDF
Article Synopsis
  • Care fragmentation in elderly patients post-hospital discharge is linked to higher morbidity and mortality, necessitating a study to identify contributing factors and their relation to mortality rates.
  • A retrospective analysis of over 447,000 patients showed that 24.3% faced unplanned readmissions within 90 days, with 20.8% experiencing care fragmentation, particularly among older females.
  • Factors like living in rural areas, low-income neighborhoods, and specific discharge decisions significantly predicted care fragmentation, which correlates with increased mortality rates in this population.
View Article and Find Full Text PDF

Background: Emergency general surgery performed among patients over 65 years of age represents a particularly high-risk population. Although interhospital transfer has been linked to higher mortality in emergency general surgery patients, its impact on outcomes in the geriatric population remains uncertain. We aimed to establish the effect of interhospital transfer on postoperative outcomes in geriatric emergency general surgery patients.

View Article and Find Full Text PDF

Introduction: General surgery procedures place stress on geriatric patients, and postdischarge care options should be evaluated. We compared the association of discharge to a skilled nursing facility (SNF) versus home on patient readmission.

Methods: We retrospectively reviewed the Nationwide Readmission Database (2016-2019) and included patients ≥65 y who underwent a general surgery procedure between January and September.

View Article and Find Full Text PDF

Purpose: For polytrauma patients with bilateral femoral shaft fractures (BFSF), there is currently no consensus on the optimal timing of surgery. This study assesses the impact of early (≤ 24 h) versus delayed (>24 h) definitive fixation on clinical outcomes, especially focusing on concomitant versus staged repair. We hypothesized that early definitive fixation leads to lower mortality and morbidity rates.

View Article and Find Full Text PDF
Article Synopsis
  • Noncompressible truncal hemorrhage is a significant cause of preventable deaths outside of hospital settings, necessitating reliable animal models to test new treatments.
  • This study created a lethal injury model using Yorkshire swine, combining severe liver damage with controlled blood volume loss, resulting in rapid and consistent outcomes.
  • The developed model consistently led to high mortality rates within a short timeframe, making it a valuable tool for evaluating interventions for severe abdominal bleeding.
View Article and Find Full Text PDF