Foot health status and associated characteristics of nursing students: a cross-sectional study.

Background: Nursing students frequently experience prolonged standing during clinical practice, which can lead to foot health disorders. Despite its critical importance for overall well-being and future job performance, foot health among nursing students remains understudied. This study aimed to examine foot health status and associated characteristics among nursing students.

Factors influencing quality of life in adolescents with type 1 diabetes mellitus: A cross-sectional study in South Korea.

Background: The promotion of quality of life for adolescents with type 1 diabetes mellitus enables them to achieve physical, psychological, and social development. Improving quality of life positively influences their well-being in adulthood.

Objective: This study aimed to identify the factors influencing quality of life in adolescents with type 1 diabetes mellitus.

Validity and Reliability of a Korean Diabetes Eating Problem Survey-Revised.

Purpose: This study was to translate the Diabetes Eating Problem Survey-Revised (DEPS-R), originally developed for adolescents with type 1 diabetes mellitus, into Korean, and to determine its factor structure while testing its validity and reliability among Korean adolescents with type 1 diabetes.

Methods: The participants were recruited from the Diabetes Center of a university hospital or type 1 diabetes camp. A total of 205 Korean adolescents aged 13-18 years diagnosed with type 1 diabetes completed a self-reported questionnaire.

Health behaviors and mental health among adolescents: A comparison based on BMI using the 2021 Korea Youth Risk Behavior Survey.

Background: Obesity and underweight can have adverse effects on adolescents. However, previous obesity management program conducted in Korea for adolescents with obesity showed low effectiveness, and there are few studies on underweight Korean adolescents.

Objective: This study aims to analyze differences in the health behaviors and mental health of adolescents based on their body mass index (BMI).

Eating disorders between male and female adolescents with type 1 diabetes mellitus in Korea.

Background: Diabetes mellitus and its prevalence are rising dramatically in Korea and throughout the world, not only in adults but in adolescents.

Objective: This study aimed to identify the sex-specific factors that influence eating disorders in adolescents with type 1 diabetes.

Methods: A secondary analysis of a descriptive survey was employed.

Clinical Application of Factor VIII:C to VWF:Ag Ratio for the Screening of Haemophilia A Carriers.

Analyses of factor VIII procoagulant activity (FVIII:C) and the FVIII:C to VWF:Ag ratio (FVIII:C/VWF:Ag ratio) have been investigated as screening bioassays to detect haemophilia carriers. This study aimed to determine the validity of the FVIII:C/VWF:Ag ratio and FVIII:C analyses as screening tests. We reviewed the medical records of 137 genetically confirmed, proband haemophilia A patients and 179 of their familial females who had undergone carrier testing.

[Predictors of Eating Disorders in Adolescents with Type 1 Diabetes].

Purpose: The purpose of this study was to identify predictors of eating disorders in adolescents with type 1 diabetes, with the goal of providing data in support of nursing interventions to improve their health.

Methods: A total of 136 adolescents aged 13-18 years with type 1 diabetes completed the Diabetes Eating Problem Survey-Revised, Rosenberg Self-Esteem Scale, and the Beck Depression Inventory-II, using structured self-reported questionnaires. The collected data were analyzed using the t-test, test, and binominal logistic regression with SPSS version 23.

Suppression of IL-2 production and proliferation of CD4(+) T cells by tuberostemonine O.

Tuberostemonine stereoisomers are natural alkaloids found in Stemona tuberosa, that are known to have anti-inflammatory and anti-infective properties. Tuberostemonine alkaloids inhibit inflammation by suppressing the expression of inflammatory mediators such as cyclooxygenase and nitric oxide synthase. However, the direct immunomodulatory properties of tuberostemonine alkaloids in T cells have not been elucidated so far.

Suppression of Inflammatory cytokine production by ar-Turmerone isolated from Curcuma phaeocaulis.

Rhizomes of Curcuma phaeocaulis Valeton (Zingiberaceae) have traditionally been used for controlling inflammatory conditions. Numerous studies have aimed to isolate and characterize the bioactive constituents of C. phaeocaulis.

Lysine 313 of T-box is crucial for modulation of protein stability, DNA binding, and threonine phosphorylation of T-bet.

A T-box-containing protein expressed in T cells (T-bet) is a key transcription factor involved in the regulation of Th cell differentiation. Although T-bet-deficient CD4(+) T cells fail to produce IFN-γ and typically differentiate into Th2 cells in vitro, ectopic overexpression of T-bet elevates IFN-γ and suppresses production of IL-2 and Th2 cytokines through different mechanisms. Despite the importance of the T-bet protein level, the regulatory mechanisms that control T-bet protein stability are largely unknown.