Disruptions in Tiopronin therapy: impacts on clinical outcomes of pediatric cystinuria patients during the COVID-19 pandemic.

Cystinuria, characterized by defective renal absorption of cystine causing recurrent nephrolithiasis, demands ongoing management. This study examines the effects of COVID-19-related disruptions in tiopronin availability on the clinical outcomes of pediatric cystinuria patients. This retrospective cohort study analyzed medical records of 11 pediatric patients with cystinuria, followed from 2001 to 2023.

Clinical outcomes and risk factors in pediatric patients with solitary functioning kidney: a comparative analysis of congenital and acquired etiologies.

Introduction: This study aims to assess the clinical outcomes and kidney function in pediatric patients with a solitary functioning kidney (SFK) due to various causes. It focuses on evaluating the glomerular filtration rate (GFR) across five groups: renal agenesis, multicystic dysplastic kidney (MCDK), atrophic kidney, hypoplastic kidney, and patients who underwent nephrectomy due to bleeding, stones, infection, or tumor without having progressed to renal failure.

Methods: A retrospective chart review was conducted on single kidneys of 396 patients seen at the pediatric nephrology clinic from January 2011 to June 2024.

Growth and puberty development in pediatric chronic kidney disease patients: Role of dialysis and transplantation.

Chronic kidney disease (CKD) is associated with growth retardation and delayed pubertal development in the pediatric population. This study aimed to investigate the impact of CKD on growth and pubertal development in children and adolescents by considering factors such as dialysis and transplantation. A cross-sectional retrospective study was conducted in a cohort of 52 pediatric patients aged 0 to 18; the patients had been diagnosed with stages 2 to 5 CKD and were undergoing dialysis treatment or kidney transplantation.

The Efficacy and Outcomes of Renal Replacement Therapy in Pediatric Metabolic Disorders.

This study aims to evaluate the efficacy and outcomes of renal replacement therapy (RRT) in pediatric patients with metabolic diseases, specifically focusing on the impact of hemodialysis (HD) and peritoneal dialysis (PD) on clinical parameters, toxin reduction, and long-term survival. This retrospective study included 10 pediatric patients (eight females and two males) treated at a pediatric nephrology department between 2020 and 2023. Patients diagnosed with metabolic disorders, including maple syrup urine disease (MSUD), methylmalonic acidemia (MMA), and glycogen storage disease (GSD), underwent RRT.