Publications by authors named "Demet Tekcan Karali"
Cystinuria, characterized by defective renal absorption of cystine causing recurrent nephrolithiasis, demands ongoing management. This study examines the effects of COVID-19-related disruptions in tiopronin availability on the clinical outcomes of pediatric cystinuria patients. This retrospective cohort study analyzed medical records of 11 pediatric patients with cystinuria, followed from 2001 to 2023.
View Article and Find Full Text PDFChronic kidney disease (CKD) is associated with growth retardation and delayed pubertal development in the pediatric population. This study aimed to investigate the impact of CKD on growth and pubertal development in children and adolescents by considering factors such as dialysis and transplantation. A cross-sectional retrospective study was conducted in a cohort of 52 pediatric patients aged 0 to 18; the patients had been diagnosed with stages 2 to 5 CKD and were undergoing dialysis treatment or kidney transplantation.
View Article and Find Full Text PDFThis study aims to evaluate the efficacy and outcomes of renal replacement therapy (RRT) in pediatric patients with metabolic diseases, specifically focusing on the impact of hemodialysis (HD) and peritoneal dialysis (PD) on clinical parameters, toxin reduction, and long-term survival. This retrospective study included 10 pediatric patients (eight females and two males) treated at a pediatric nephrology department between 2020 and 2023. Patients diagnosed with metabolic disorders, including maple syrup urine disease (MSUD), methylmalonic acidemia (MMA), and glycogen storage disease (GSD), underwent RRT.
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- - The study investigated congenital anomalies of the kidney and urinary tract (CAKUT) in children, focusing on factors leading to the need for ureterorenal surgery by analyzing 651 cases for demographics, genetic mutations, and ultrasound findings.
- - Findings revealed that a significant proportion of patients had hydronephrosis (46.9%), and surgical intervention was linked to better outcomes in reducing hydronephrosis compared to those who did not undergo surgery.
- - Risk factors for genetic mutations included low neonatal birth weight, advanced maternal age, and abnormal postnatal ultrasounds, while antenatal hydronephrosis and postnatal urinary tract infections increased the likelihood of requiring surgical intervention.
Introduction: Continuous ambulatory peritoneal dialysis is an important modality of renal replacement therapy in children. Catheter dysfunction (commonly obstruction) is a major cause of morbidity and is a significant concern that hampers renal replacement therapy. As omentum is a significant cause of obstruction, some recommend routine omentectomy during insertion of the peritoneal dialysis catheter.
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- Myelomeningocele (MMC) is a condition that affects many kids in developing countries like Turkey, and it can lead to kidney problems known as chronic kidney disease (CKD).
- A study in Turkey looked at children with MMC to find out how many had different stages of CKD and what factors made their kidney health worse.
- The results showed that 5.3% of the kids had CKD stage 5, and certain medical conditions were linked to an increased risk of serious kidney problems. To help these kids, doctors suggest taking early action in managing their bladder issues to prevent kidney failure.
Introduction: This report provides insight into three distinct pediatric cases exhibiting a nexus between multisystem inflammatory syndrome in children (MIS-C) and thrombotic microangiopathy (TMA) triggered by COVID-19. The aim is to underscore the range of clinical presentations and the essentiality of early interventions.
Case Presentations: This report presents three cases aged 10 months, 7 years, and 3 years with persistent fever, diarrhea, nausea, and vomiting.