Publications by authors named "Hui-Fang Chen"

Background: Mitochondria are essential for cellular energy production and cell survival. Mitochondrial dysfunction has been implicated in various neurological disorders, prompting the development of novel therapeutic approaches targeting these organelles. Among these, mitochondrial transplantation (MT), which replaces dysfunctional mitochondria with healthy counterparts from donor tissues, has emerged as a promising strategy.

View Article and Find Full Text PDF

: Transitional attachment objects, such as blankets, play a critical role in childhood by helping children manage separation anxiety and regulate emotions. Although attachment to these objects often decreases as children grow older, it may persist into adulthood and influence emotion regulation and stress responses. Their influence on emotion regulation in adulthood remains uncertain.

View Article and Find Full Text PDF

Background: Amidst the expansion of student enrollment in higher education, the well-being and retention rates of students have emerged as important concerns. Resilience, especially academic resilience, a multidimensional construct that can lead to academic success in adversity, is pivotal in enabling students to successfully cope with academic challenges. While the Academic Resilience Scale-30 (ARS-30) has been validated as an effective instrument in various languages, its applicability for Chinese students in higher education remains unexplored.

View Article and Find Full Text PDF

Background: Satellite glial cells (SGCs) in the dorsal root ganglia (DRG) play a pivotal role in the formation of neuropathic pain (NP). Sciatic nerve stimulation (SNS) neuromodulation was reported to alleviate NP and reduce neuroinflammation. However, the mechanisms underlying SNS in the DRG remain unclear.

View Article and Find Full Text PDF

Purpose: This study investigated the mechanism underlying the association between intolerance of uncertainty and mobile phone addiction among Chinese overseas students during the COVID-19 pandemic by examining the mediating roles of perceived stress and rumination.

Patients And Methods: An online questionnaire survey was distributed via social media platforms popular in mainland China. The items collected demographic information and assessed intolerance of uncertainty, perceived stress, rumination, and mobile phone addiction.

View Article and Find Full Text PDF

Introduction: Allergic rhinitis (AR) is a respiratory immune system disorder characterized by dysregulation of immune responses. Within the context of AR, gut microbiota and its metabolites have been identified as contributors to immune modulation. These microorganisms intricately connect the respiratory and gut immune systems, forming what is commonly referred to as the gut-lung axis.

View Article and Find Full Text PDF

Background: Published studies on the association between lithium use and the decreased risk of major neurocognitive disorders (MNCDs) have shown disparities in their conclusions. We aimed to provide updated evidence of this association.

Methods: A comprehensive literature search was performed in PubMed, EMBASE, and Cochrane Library from inception until August 31, 2023.

View Article and Find Full Text PDF
Article Synopsis
  • The study investigates the effects of different compression durations on spinal cord injury severity using a rat model, revealing a link between longer compression times and more severe deficits.
  • Results indicated significant injuries even with just 1 second of compression, paralleling moderate-to-severe SCI outcomes.
  • The research highlights the need to consider both compression duration and clip deformation in designing SCI experiments, which can influence data interpretation in preclinical studies.
View Article and Find Full Text PDF
Article Synopsis
  • * Mitochondrial dysfunction and neuroinflammation are key factors in the development of TNP, and recent studies have explored mitochondrial transplantation (MT) as a potential treatment.
  • * In experiments with rat models, MT showed promise in reducing pain hypersensitivity and neuroinflammation associated with TNP, suggesting it could offer neuroprotective benefits against this type of pain.
View Article and Find Full Text PDF

Parental hostility and emotional rejection-or aggregated as general harsh family interactions with parents-have received little research attention due to such parent-child interactions being counted as minor forms of parental maltreatment and regarded as being less harmful. However, recent research showed that these minor forms of parental maltreatment on youth development are far from negligibility on account of their frequency, chronicity, and incessancy. In this longitudinal study, we investigated how parental hostility, emotional rejection, and harsh family interactions with parents of in early adolescence of immigrant youths (wave-1 M = 14) adversely impact successful college graduation of immigrant youths in young adulthood (wave-3 M = 24) through the mediation of their development of academic aspirations in late adolescence (wave-2 M = 17).

View Article and Find Full Text PDF

Introduction: As one of the most common allergic diseases, allergic rhinitis (AR) has attracted wide attention all over the world. More appropriate treatment of AR should be explored thoroughly. In recent years, traditional Chinese medicine has attracted more attention in AR treatment.

View Article and Find Full Text PDF

Although the twenty-first century is deemed as a new era of globalization, waves of immigration continue, due to disparities between politically and economically unstable regions and Western democratized and developed countries. Immigration research has therefore reignited its attention on the successful adaptation of immigrants' offspring, which has profound implications for Western immigrant-receiving countries, as well as worldwide stability. Although immigration research mainly informed by the conventional assimilation theory and/or segmented assimilation perspective accentuates the importance of structural factors, termed as social forces here, in relation to immigrant children's successful adaptation in adolescence, an argument of determinism and tenability keeps on and the contribution of human mental resources and determination, termed as mental forces here, in shaping life trajectories of immigrant children should be not ignored.

View Article and Find Full Text PDF
Article Synopsis
  • * A study on traumatic SCI in rats showed that transplanting allogeneic mitochondria improved recovery in locomotor and sensory functions, with detectable effects lasting up to 28 days.
  • * Mitochondrial transplantation helped reduce cell death, inflammation, and oxidative stress in the injured spinal cord, leading to better overall recovery after SCI.
View Article and Find Full Text PDF

Since the start of the COVID-19 pandemic, individuals have been encouraged to engage in health-promoting behaviors, namely actions taken to prevent infection and keep themselves healthy, such as maintaining social distancing. However, other factors, such as risk perception and feelings of fear, also might influence whether an individual takes such measures. This study compared people's responses to the pandemic in terms of their adoption of COVID-19 health-promoting behaviors, COVID-19 risk perceptions, and attention to COVID-19-related information during two periods: the 2020 Chinese New Year (CNY) in Hong Kong (HK), i.

View Article and Find Full Text PDF

The abnormal deposition of the extracellular amyloid-β peptide is the typical pathological hallmark of Alzheimer's disease. Strategies to reduce the amyloid-β deposition effectively alleviate the neuronal degeneration and cognitive deficits of Alzheimer's disease. Danggui-Shaoyao-San has been considered a useful therapeutic agent known for the treatment of Alzheimer's disease.

View Article and Find Full Text PDF

Purpose: The purposes of this study were to develop a new measure, the Facilitators and Barriers to Physical Activity Scale for People with Mental Illness (FBPAS-MI) and to validate the psychometrics.

Methods: This study included two phases. In Phase I, a literature review and five focus groups were conducted to develop an item bank.

View Article and Find Full Text PDF

Background: This study aimed to evaluate the differences in nurses' willingness to discuss palliative care with terminally ill patients and their family members.

Methods: The participants were randomly recruited from registered staff nurses ≥20 years of age who were responsible for clinical inpatient care in a tertiary hospital in northern Taiwan. A semi-structured questionnaire was administered to evaluate nurses' experiences of discussing do-not-resuscitate (DNR) decisions and their willingness to discuss palliative care with terminal patients and their family members.

View Article and Find Full Text PDF

A combination of positively and negatively worded items (termed a mixed-format design) has been widely adopted in personality and attitude assessments. While advocates claim that the inclusion of positively and negatively worded items will encourage respondents to process the items more carefully and avoid response preference, others have reported that negatively worded (NW) items may induce a nuisance factor and contaminate scale scores. The present study examined the extent of the impact of the NW-item feature and further investigated whether a mixed-format design could effectively control acquiescence and the preference for extreme response options using two datasets (Attitude toward Peace Walls, and International Personality Item Pool).

View Article and Find Full Text PDF

Parental socialization has been recently reported as a multifaceted concept, which includes parenting practices and family processes. Nevertheless, prior family research generally treated parental socialization tantamount to parenting behavior only and overlooked its different effects on multiple youth outcomes simultaneously, especially in the Chinese population. This study, with a sample of 223 Chinese parent-youth dyads (80.

View Article and Find Full Text PDF

Likert or rating scales may elicit an extreme response style (ERS), which means that responses to scales do not reflect the ability that is meant to be measured. Research has shown that the presence of ERS could lead to biased scores and thus influence the accuracy of differential item functioning (DIF) detection. In this study, a new method under the multiple-indicators multiple-causes (MIMIC) framework is proposed as a means to eliminate the impact of ERS in DIF detection.

View Article and Find Full Text PDF

Differential item functioning (DIF) makes test scores incomparable and substantially threatens test validity. Although conventional approaches, such as the logistic regression (LR) and the Mantel-Haenszel (MH) methods, have worked well, they are vulnerable to high percentages of DIF items in a test and missing data. This study developed a simple but effective method to detect DIF using the odds ratio (OR) of two groups' responses to a studied item.

View Article and Find Full Text PDF

Conventional differential item functioning (DIF) approaches such as logistic regression (LR) often assume unidimensionality of a scale and match participants in the reference and focal groups based on total scores. However, many educational and psychological assessments are multidimensional by design, and a matching variable using total scores that does not reflect the test structure may not be good practice in multidimensional items for DIF detection. We propose the use of all subscores of a scale in LR and compare its performance with alternative matching methods, including the use of total score and individual subscores.

View Article and Find Full Text PDF

Extreme response styles (ERS) is prevalent in Likert- or rating-type data but previous research has not well-addressed their impact on differential item functioning (DIF) assessments. This study aimed to fill in the knowledge gap and examined their influence on the performances of logistic regression (LR) approaches in DIF detections, including the ordinal logistic regression (OLR) and the logistic discriminant functional analysis (LDFA). Results indicated that both the standard OLR and LDFA yielded severely inflated false positive rates as the magnitude of the differences in ERS increased between two groups.

View Article and Find Full Text PDF