Publications by authors named "Hong-juan Niu"
Since the chromatographic fingerprint was introduced, it has been accepted by many countries to assess the quality and authenticity of Chinese herbal medicine (CHM). However, solely using the chromatographic fingerprint to assay numerous chemicals is not suitable for the assessment of the whole internal quality and pharmacodynamics of CHM. Consequently, it is necessary to develop a rational approach to connecting the chromatographic fingerprint with effective components to assess the internal quality of CHM.
View Article and Find Full Text PDF[Molecular docking analysis of xanthine oxidase inhibition by constituents of cichory].
Zhongguo Zhong Yao Za Zhi
October 2015
Article Synopsis
- Human xanthine oxidase is a key target for treating high uric acid levels, and Cichorium intybus (cichory) is used in traditional Chinese medicine for various health issues.
- A collection of compounds from C. intybus was created based on research, and the three-dimensional structure of xanthine oxidase was obtained for analysis.
- Autodock 4.2 identified 70 compounds from cichory with low binding energy against xanthine oxidase, suggesting that cichory may effectively reduce serum uric acid levels due to its inhibitor properties.