Treatment Satisfaction, Efficacy, and Safety of Delgocitinib Ointment Following Switch From Topical Corticosteroids for Trunk and Extremity Rash in Atopic Dermatitis.

Atopic dermatitis (AD) is a chronic inflammatory disease characterized by recurrent remissions and relapses. Topical anti-inflammatory steroids are commonly used for treatment, but their long-term use poses concerns because of potential side effects. Delgocitinib ointment, a Janus kinase inhibitor, has demonstrated efficacy in several clinical studies and is expected to be a viable alternative to topical corticosteroids (TCS).

Treatment Satisfaction, Efficacy, and Safety of Delgocitinib Ointment for Atopic Dermatitis-Induced Rash on the Face and Neck: Efficacy at Reducing Local Side Effects of Topical Steroid and Tacrolimus Ointment.

This open-label, single-arm, multicenter clinical study evaluated the treatment satisfaction, efficacy, and safety of 0.5% delgocitinib ointment twice daily for 12 weeks, applied to face/neck lesions caused by ≥ 3 months use of topical steroids or tacrolimus ointment in patients with atopic dermatitis (AD). The primary endpoint was change in treatment satisfaction (Treatment Satisfaction Questionnaire for Medication-9 [TSQM-9]).

Needs-based job crafting: Validation of a new scale based on psychological needs.

We present the conceptualization and validation of the Needs-Based Job Crafting Scale (NJCS), a new assessment tool theoretically grounded in the Identity-Based Integrative Needs Model of Crafting and DRAMMA psychological needs (detachment, relaxation, autonomy, mastery, meaning, and affiliation). The article is composed of three studies. In Study 1, we develop the NJCS and test its factorial structure using a cross-sectional sample of Finnish employees (N = 578).

Needs-based off-job crafting across different life domains and contexts: Testing a novel conceptual and measurement approach.

Shaping off-job life is becoming increasingly important for workers to increase and maintain their optimal functioning (i.e., feeling and performing well).

School Principals' Stress Profiles During COVID-19, Demands, and Resources.

The present study examined latent profiles of school principals' stress concerning students', teachers', parents', and principals' own ability to cope during the COVID-19 pandemic. In addition, the role of job demands (workload, remote work stress, difficulty to detach from work, COVID-19 crisis, COVID-19 infections at school, impact of COVID-19 on future teaching), resources (buoyancy, effective crisis leadership, social appreciation, successful transition to remote teaching), and occupational well-being (measured as job burnout and engagement) in predicting the latent profiles of stress sources was examined. The participants were 535 (59% women) school principals across Finland, who answered to a questionnaire concerning their sources of stress and occupational well-being during spring 2020.

The Forgotten Ones: Crafting for Meaning and for Affiliation in the Context of Finnish and Japanese Employees' Off-Job Lives.

In an intensifying working life, it is important for employees to proactively shape their lives beyond work to create opportunities for satisfying personal needs. These efforts can be beneficial for creating and sustaining well-being in terms of vitality. In this study, we focused on off-job crafting (OJC) for meaning and OJC for affiliation, conceptualized as proactive changes in off-job life with the aim of increasing satisfaction of needs for meaning and affiliation, among employees in Finland and Japan, two countries with disparate cultural values.

Validation of the Japanese Version of the Burnout Assessment Tool.

The current study aimed to validate the Japanese version of the Burnout Assessment Tool (BAT-J), a new burnout measure. We conducted an Internet survey to confirm the validity and reliability of the BAT-J, using registered monitors from a Japanese survey company. The first-wave survey was conducted in May 2018, with 1,032 monitors.

[A case of pancreatic cancer treated by gemcitabine with sequential radiotherapy].

A 65-year-old man suffering from acute pancreatitis underwent MRI scanning, which revealed a low signal on the T1 and T2 sequences, and hypovascularity in arterial phase in the head of the pancreas. This corresponded to the area showing the absence of the lower common bile duct. FDG-PET was highly suggestive of pancreatic cancer (T4N1M0, Stage IVa) with lymph node metastasis.