Under pressure: Unraveling the impact of occlusal overload on peri-implant health-A systematic review.

Purpose: To evaluate the impact of occlusal trauma and excessive occlusal loading on dental implant health, with a focus on marginal bone loss and the incidence of peri-implantitis. The review aims to clarify how nonphysiological occlusal forces influence stress distribution around implants and contribute to clinical complications.

Methods: A systematic search was conducted across PubMed, Scopus, Web of Science, and the Cochrane Library for studies published between January 2000 and October 2023.

Clinical Translation of the 2024 AO/AAP Consensus on Prevention and Management of Peri-implant Diseases and Conditions.

As the number of placed implants increases exponentially worldwide, the prevalence of peri-implant diseases, namely mucositis and peri-implantitis, is also in an ascending trajectory. Focusing on prevention and identifying and decreasing risk factors are important aspects of managing the epidemic of peri-implant diseases. However, many clinicians are faced with patients who already have signs of inflammatory disease in varying degrees of severity.

Advancing Peri-Implantitis Treatment: A Scoping Review of Breakthroughs in Implantoplasty and Er:YAG Laser Therapies.

Background: Peri-implantitis represents a significant challenge in dental implantology, characterized by inflammatory reactions around osseointegrated dental implants that lead to progressive alveolar bone loss.

Objectives: To generate a scoping review that evaluates the efficacy of implantoplasty and Er:YAG laser therapies in managing peri-implantitis by synthesizing recent evidence on their impact on key clinical parameters-including probing depth reduction, bleeding on probing improvement, and marginal bone level stabilization-and to explore the potential synergistic benefits of combining these modalities for enhanced treatment outcomes.

Material And Methods: A comprehensive search was conducted in PubMed, EMBASE, the Cochrane Library, and Web of Science for studies published from January 2018 to the present.

An Organic Mineral Adhesive Bone Graft: A Preclinical Study.

Purpose: To evaluate four formulations of tetracalcium phosphate combined with phosphoserine (TTCP-PS) in comparison to the conventional grafting materials bioglass (BG) and deproteinized cancellous bovine bone with a bioresorbable collagen membrane in standardized defects created in the angle of the rat mandible.

Materials And Methods: TTCP-PS is a synthetic, injectable, cohesive, self-setting, mineral-organic wet-field adhesive. Microcomputed tomography (microCT) and histomorphometry were used to evaluate bone replacement with each of these materials after in vivo residence of either 4 or 12 weeks.

Photobiomodulation in dental extraction therapy: Postsurgical pain reduction and wound healing.

Background: This scoping review and analysis were designed to assess the amount of time spent delivering photobiomodulation (PBM) light therapy after dental extraction to improve postoperative pain and wound healing.

Types Of Studies Reviewed: The scoping review was performed according to the Cochrane Collaboration and Preferred Reporting Items for Systematic Reviews and Meta-Analyses criteria. Publications were specific for human randomized controlled clinical trials, PBM after dental extraction therapy, and related clinical outcomes.

Immune changes over time and survival in patients with cirrhosis treated with non-selective beta-blockers: A prospective longitudinal study.

Background: Treatment with non-selective beta-blockers (NSBB) has been associated with anti-inflammatory and anti-cancer effects in patients with cirrhosis. This study aims to analyze the impact of chronic NSBB treatment on immune activation and disease progression in stable outpatients with cirrhosis.

Methods: In this prospective follow-up of 150 patients with cirrhosis, 39 received treatment with NSBB.

Improving Titanium Implant Stability with Photobiomodulation: A Review and Meta-Analysis of Irradiation Parameters.

This analysis was designed to present a summary of available evidence that will inform practice and guide future research for photobiomodulation (PBM) after titanium implant placement procedures. A systematic review was performed according to the Cochrane Collaboration and in line with Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) criteria. Two investigators screened the titles and abstracts, and reviewed articles for risk of bias.

A Revised Peri-implantitis Classification Scheme: Adding Three-Dimensional Considerations to Facilitate Prognosis and Treatment Planning.

Historically, diagnosing peri-implantitis is done based on whether the disease is present, evaluated using the arbitrary thresholds of probing depths and bone loss. Using this approach as a tool to ascertain meaningful information regarding prevalence and treatment is limited. Efforts have been made to improve upon this, but to date, only one of these classifications has provided a simple method to communicate disease severity based on the amount of bone loss.

Flow cytometry detection of sustained humoral immune response (IgG + IgA) against native spike glycoprotein in asymptomatic/mild SARS-CoV-2 infection.

SARS-CoV-2 is the virus that causes the disease called COVID-19, which has caused the worst pandemic of the century. Both, to know the immunological status of general population and to evaluate the efficacy of the vaccination process that is taking place around the world, serological tests represent a key tool. Classic serological tests, based on colorimetric techniques, such as ELISA or CLIA, continue to be the most widely used option.

A Modified Bilaminar Technique with the Use of a Fibrin-Fibronectin System for a Single Gingival Recession: A Case Report with a Follow-Up of 3 Years.

This case report described a modified bilaminar technique for treating a single gingival recession. Patient presented a gingival recession in a maxillary canine. Tooth was in a buccally prominent position and soft keratinized tissue apical to the recession was reduced but still present.

Healed Edentulous Sites: Suitability for Dental Implant Placement, Need for Secondary Procedures, and Contemporary Implant Designs.

Purpose: The purpose of this retrospective computed tomography study was to evaluate bone availability for dental implant placement, frequency of bone augmentation procedures, frequency of anatomical structures that compromise implant placement, and frequency of implant dimensions, and to determine which edentulous sites would benefit from the use of a sloped implant versus a traditional flat design.

Materials And Methods: Recorded parameters included the width of the ridge, the buccal and lingual/palatal alveolar bone height in reference to different anatomical landmarks, determination of implant placement, selection of an implant with a flat or sloped top, and need for a secondary bone augmentation procedure.

Results: One thousand three hundred seventy edentulous sites were evaluated in 216 patients.

The Long-Term Evaluation of Two-Unit Fixed Partial Dentures on Short, Threaded Implants: Delayed Versus Immediate Loading.

Placement of short implants is a common approach to rehabilitate edentulous areas. The objective of this study was to evaluate the long-term survival of 7.0- and 8.

Peri-implant Mucosal Tissues and Inflammation: Clinical Implications.

Purpose: The purpose of this review was to explore the available literature and compile studies that discuss the relevance of the biofilm, onset and progression of disease, critical peri-implant pocket depth, frequency of supportive implant therapy, excess cement, and keratinized peri-implant tissues as related to peri-implant disease.

Materials And Methods: PubMed, Cochrane Oral Health Group Specialized Trial Register, and hand searches of related journals were performed in relationship to the focused question. Reports describing techniques, preclinical studies, and case reports were excluded.

Multiparameter Flow Cytometry Identification of Neoplastic Subclones: A New Biomarker in Monoclonal Gammopathy of Undetermined Significance and Multiple Myeloma.

Multiparameter flow cytometry (MFC)-based clonality assessment is a powerful method of diagnosis and follow-up in monoclonal gammopathy of undetermined significance (MGUS) and multiple myeloma (MM). However, the relevance of intraclonal heterogeneity in immunophenotypic studies remains poorly understood. The main objective of this work was to characterize the different immunophenotypic subclones in MGUS and MM patients and to investigate their correlation with disease stages.

Surgical Alternatives for Treating Peri-implantitis.

The objective of this case series was to describe surgical approaches that can be used to efficiently and effectively treat peri-implantitis as measured by positive changes in clinical parameters. A total of 32 patients with 45 implants were treated surgically to eliminate peri-implantitis. Baseline clinical parameters measured prior to surgery were compared to those made 6 months postsurgery to evaluate the efficacy of each procedure.

Alveolar Ridge Augmentation with Three-Dimensional Printed Hydroxyapatite Devices: A Preclinical Study.

The objective of this study was to evaluate the effectiveness of precise three-dimensional hydroxyapatite printed micro- and macrochannel devices for alveolar ridge augmentation in a canine model. All grafts induced minimal inflammatory and fibrotic reactions. Examination of undecalcified sections revealed that both types of grafts demonstrated bone ingrowth.

A Rare Case of Pure Erythroid Sarcoma in a Pediatric Patient: Case Report and Literature Review.

We describe an exceptional case of erythroid sarcoma in a pediatric patient as a growing orbital mass with no evidence of morphologic bone marrow involvement, who was finally diagnosed of pure erythroid sarcoma based on histopathology and flow cytometry criteria. We discuss the contribution of standardized eight-color flow cytometry as a rapid and reliable diagnostic method. The use of normal bone marrow databases allowed us to identify small aberrant populations in bone marrow and later confirm the diagnosis in the neoplastic tissue.

The Use of Recombinant Human Platelet-Derived Growth Factor for Maxillary Sinus Augmentation.

The maxillary sinus augmentation procedure has become a predictable treatment to regenerate bone for implant placement. The purpose of this study was to evaluate the effect of recombinant human platelet-derived growth factor BB (rhPDGF-BB) combined with a deproteinized cancellous bovine bone graft for sinus augmentation. The lateral window approach was used for maxillary sinuses with minimal residual bone.

The Effect of Osteopontin and an Osteopontin-Derived Synthetic Peptide Coating on Osseointegration of Implants in a Canine Model.

Osteopontin (OPN) and an OPN-derived synthetic peptide, OC-1016, have demonstrated their potential to enhance osseointegration in vitro. The purpose of this study was to evaluate bone-to-implant contact (BIC) and surrounding bone density (BD) of implants coated with either recombinant human OPN (rhOPN) or OC-1016 as compared with noncoated titanium plasma sprayed (TPS) surface in a canine model. Histomorphometric analysis revealed that at 4 weeks, %BIC and %BD of coated implants were significantly higher than those of noncoated TPS implants.

A Classification System for Peri-implant Diseases and Conditions.

Peri-implant bone levels are influenced by pathologic and nonpathologic conditions. The understanding of peri-implant disease has evolved over the past several decades, and the classification of peri-implantitis has been limited to descriptions of disease progression or those involving soft and/or hard tissues (peri-implant mucositis or peri-implantitis). However, no classification system has been established based on etiology.

A Palatal Approach for a Sinus Augmentation Procedure.

The purpose of this article is to demonstrate an alternative method for sinus augmentation through a palatal approach when complications do not allow the use of traditional approaches. A 50-year-old male patient presented with multiple previous sinus augmentation attempts. A cone beam computed tomography scan revealed bone graft material had consolidated on the buccal aspect of the lateral sinus wall only, preventing implant placement while not allowing access via a conventional lateral window technique to improve the graft bulk.

Prevalence of torus mandibularis in Rochester, New York, region.

The purpose of this study was to investigate the prevalence of torus mandibularis within a population residing in the Rochester, New York, region. During a comprehensive initial exam, utilizing clinical inspection and palpation, 1,323 subjects were examined for any tori in the mandibular area. Of the 1,323 subjects studied, 37.

Measles outbreak in Venezuela: a new challenge to postelimination surveillance and control?

The circulation of wild measles virus was interrupted in Venezuela in February 2007 after the catch-up vaccination (1994) and monitoring (1998) and in response to the measles outbreak in 2001. Traditionally, the routine coverage with measles-mumps-rubella vaccine does not exceed 85%. In February 2006, a measles outbreak started by importation in the State Miranda; this extended to 7 states and lasted 50 weeks with an intermediate period of 17 weeks without reported cases.