Diurnal Encounter-Based Size Distribution, Nesting Sites and Habitat Characteristics of the Mugger Crocodile () in Beeshazari Lake Complex, Nepal.

Mugger crocodiles are the apex predator species of the wetland ecosystem in Nepal, and their conservation could safeguard the entire ecosystem. However, studies on their population status and habitat characteristics are limited, with no scientific research conducted on their nesting ecology to date. Therefore, we selected muggers as a representative species to better understand their daytime sightings, nesting characteristics, and the fine-scale anthropogenic and environmental factors influencing their occurrence in five lakes of the Beeshazari Lake complex (BLC; Beeshazar Lake, Kumal Lake, Tikauli Lake, Kingfisher Lake, and Batuli Pokhari) of Chitwan National Park, Nepal.

Impact of invasive alien plants on the resident floral diversity in Koshi Tappu Wildlife Reserve, Nepal.

Invasive alien plant species (IAPS) pose a serious threat to overall plant biodiversity across the globe. Nepal's national parks and protected areas are not devoid of the impact of IAPS. Unfortunately, there is a substantial gap in knowledge regarding the extent and impact of invasion in protected areas of Nepal.

Reviving lost shadows: investigating the habitat ecology of the rediscovered hispid hare () in Nepal.

The endangered hispid hare () is one of the least studied mammal species. The recent rediscovery of hispid hare in Chitwan National Park (CNP) after three decades, necessitated urgent conservation measures. A detailed investigation into the species' ecology is imperative for developing evidence-based conservation strategies to support these efforts.

Asiatic Black Bear-Human Conflict: A Case Study from Guthichaur Rural Municipality, Jumla, Nepal.

Our study assessed patterns of Asiatic black bear ()-human conflicts within the Guthichaur rural municipality, Jumla, Nepal. Through semi-structured interviews with villagers, focus group discussions (FGDs), and key informant interviews (KIIs), we gathered black bear-human conflict information from 2009 to 2019. We identified three primary types of black bear-human interactions: crop damage, livestock depredation, and human injuries.

Scleral Necrosis in a Case of Seasonal Hyperacute Panuveitis Successfully Treated with Amniotic Membrane Graft: A Case Report.

Introduction: Seasonal hyperacute panuveitis (SHAPU) is still a dilemma in the field of ophthalmology. Every alternate odd year from September until January, children usually present with unilateral painless red eyes if not treated in a timely manner, rapidly progressing to phthisis bulbi.

Case: Case was also diagnosed as a case of seasonal hyperacute panuveitis.

Landscape predictors influencing livestock depredation by leopards in and around Annapurna Conservation Area, Nepal.

Livestock depredation by leopards is a pervasive issue across many Asian and African range countries, particularly in and around protected areas. Developing effective conflict mitigation strategies requires understanding the landscape features influencing livestock depredation. In this study, we investigated predictors associated with livestock depredation by leopards using 274 cases of leopard attacks on livestock that occurred between 2017 and 2020 in the Annapurna Conservation Area, Nepal.

Habitat suitability of four threatened Himalayan species: Asiatic black bear, common leopard, musk deer, and snow leopard.

Background: Biodiversity conservation is becoming challenging day by day. For this, it is essential to understand the distribution, habitat, and impact of anthropogenic activities on animals at risk. We assessed the suitable habitats and anthropogenic impacts on Asiatic black bears, common leopards, musk deer, and snow leopards in and outside the protected areas of Gandaki Province, Nepal.

Knowledge, Attitude, and Practice of Antibiotic Use and Resistance among Poultry Farmers in Nepal.

The abuse and misuse of antibiotics is one of the main drivers of antimicrobial resistance (AMR). Globally, AMR in food-producing animals is a significant public health concern. This study, therefore, assessed the knowledge, attitudes, and practices related to antibiotic usage (AMU) and AMR among poultry farmers in Nepal.

Synthesis, characterization, and anticancer activity of chitosan functionalized isatin based thiosemicarbazones, and their copper(II) complexes.

The one-pot synthetic method of condensation of isatin and 5-chloroisatin on to amino group at C2 position of the pyranose ring chitosan in chitosan thiosemicarbazide was employed to get these chitosan thiosemicarbazones (TSCs). The partial incorporation of thiosemicarbazone moiety in chitosan was shown by FT-IR and C NMR spectroscopic studies, powder X ray diffraction, and CHNS microanalysis. The NOS tridentate coordination behavior of TSCs with copper(II) chloride to give the square planar complexes was established by FT-IR spectroscopic data, magnetic susceptibility measurement, and EPR spectral analysis.

Habitat Suitability and Conflict Zone Mapping for the Blue Bull () across Nepal.

Rapidly changing environmental conditions (bioclimatic, anthropogenic, topographic, and vegetation-related variables) are likely to alter the spatial distribution of flora and fauna. To understand the influence of environmental variables on the Blue bull's distribution and to identify potential conflict zones, the habitat suitability analysis of the Blue bull was performed using ensemble modeling. We modelled the distribution of the Blue bull using an extensive database on the current distribution of the Blue bull and selected 15 ecologically significant environmental variables.

Pyridine-Based NNS Tridentate Chitosan Thiosemicarbazones and Their Copper(II) Complexes: Synthesis, Characterization, and Anticancer Activity.

Chitosan-functionalized pyridine-based thiosemicarbazones and their copper(II) complexes have been found to own a substantial antiproliferative activity against the tumorigenic Madin Darby canine kidney (MDCK) and MCF-7 cancer cell lines. In the current study, chitosan oligosaccharide (CS) (87% DDA, M < 3000 Da) and crab shell chitosan (CCS) (67% DDA, 350 kDa) were functionalized as chitosan pyridine-2-thiosemicarbazones and chitosan 2-acetyl pyridine-2-thiosemicarbazones, and their copper(II) complexes were synthesized. The formation of chitosan thiosemicarbazones and their NNS tridentate behavior to give the square planar copper(II) chitosan thiosemicarbazone complexes were established by spectroscopic studies, powder X-ray diffraction, elemental analysis, and magnetic moment measurements.

Hybridization may aid evolutionary rescue of an endangered East African passerine.

Introgressive hybridization is a process that enables gene flow across species barriers through the backcrossing of hybrids into a parent population. This may make genetic material, potentially including relevant environmental adaptations, rapidly available in a gene pool. Consequently, it has been postulated to be an important mechanism for enabling evolutionary rescue, that is the recovery of threatened populations through rapid evolutionary adaptation to novel environments.

Pain Perception in Cataract Surgery: Topical versus Peribulbar Anaesthesia.

Introduction: The requirement for very deep akinesia has decreased with the use of modern phacoemulsification technique for cataract surgery. The use of topical anesthesia has increased as a way to reduce complications associated with anaesthesia with injection and to allow the most rapid visual recovery. The objective of this study was to assess the patient reported pain in phacoemulsification cataract surgery under topical anaesthesia versus peribulbar anaesthesia administered using an injection.

Butterfly species diversity and their floral preferences in the Rupa Wetland of Nepal.

Floral attributes often influence the foraging choices of nectar-feeding butterflies, given the close association between plants and these butterfly pollinators. The diversity of butterflies is known to a large extent in Nepal, but little information is available on the feeding habits of butterflies. This study was conducted along the periphery of Rupa Wetland from January to December 2019 to assess butterfly species diversity and to identify the factors influencing their foraging choices.

Assessing Profile and Treatment Outcome in Patients of Ocular Surface Squamous Neoplasia (OSSN).

Purpose: This study has attempted to assess the profile and treatment outcome of patients with OSSN and report the recurrence rate following treatment of primary OSSN.

Materials And Methods: This was a retrospective, non-comparative hospital based observational study. The case files of OSSN patients from Jan 2010 to Dec 2017were assessed.

Climatic impacts of bushland to cropland conversion in Eastern Africa.

Bushlands (Acacia-Commiphora) constitute the largest and one of the most threatened ecosystems in East Africa. Although several studies have investigated the climatic impacts of land changes on local and global climate, the main focus has been on forest loss and the impacts of bushland clearing thus remain poorly understood. Measuring the impacts of bushland loss on local climate is challenging given that changes often occur at fragmented and small patches.

The case of the grass-eating suids in the Plio-Pleistocene Turkana Basin: 3D dental topography in relation to diet in extant and fossil pigs.

Two separate subfamilies of Plio-Pleistocene African pigs (suids) consecutively evolved hypsodont and horizodont molars with flat occlusal surfaces, commonly interpreted as an adaptive trait to a grazing diet, similar to that of the present warthogs (Phacochoerus spp.). To investigate this in detail, we studied the 3D-dental topography of fossil specimens from the Turkana Basin, using geographic information systems-based methods.

Comparative evaluation of microleakage after root-end resection by erbium, chromium: Yttrium-scandium-gallium-garnet (Er, Cr:YSGG) laser and carbide bur with or without placement of mineral trioxide aggregate: An study.

Background: Root-end resection followed by retrofilling is one of the prime requisites to avoid apical microleakage.

Aim: It comparatively evaluated the microleakage after root-end resection by erbium, chromium:yttrium, scandium, gallium, and garnet laser and carbide bur with or without placement of mineral trioxide aggregate (MTA).

Materials And Methods: In this study, 60 maxillary central incisors were decoronated and biomechanically prepared.

Anticancer Activity of Chitosan, Chitosan Derivatives, and Their Mechanism of Action.

Tailoring of chitosan through the involvement of its amino, acetamido, and hydroxy groups can give derivatives of enhanced solubility and remarkable anticancer activity. The general mechanism of such activity is associated with the disturbances in normal functioning of cell cycle, interference to the central dogma of biological system from DNA to RNA to protein or enzymatic synthesis, and the disruption of hormonal path to biosynthesis to inhibit the growth of cancer cells. Both chitosan and its various derivatives have been reported to selectively permeate through the cancer cell membranes and show anticancer activity through the cellular enzymatic, antiangiogenic, immunoenhancing, antioxidant defense mechanism, and apoptotic pathways.

Co morbidities among cataract- operated patients in Rural Nepal.

Introduction: Himalaya Eye Hospital (HEH), established in 1993, is providing eye care services in Gandaki, Dhaulagiri and Karnali zones. It has been providing surgical and nonsurgical eye camps in rural areas of Gandaki, Dhaulagiri and Karnali zones. The aim of this study was to determine the prevalence of ocular and systemic co morbidities among the persons treated in rural Asian setting.

Penetrating head injury with bilateral eye avulsion due to Himalayan bear bite.

The Himalayan black bear (Ursus thibetanus or Selenarctos thibetanus), although an omnivore, is more carnivorous than its American counterpart. It is also more aggressive towards humans and is a threatened species because of the deforestation in the Himalayas. Furthermore, poverty, encroachment of the forest, extensive deforestation, lack of education and living near the forest are factors that increase the probability of such animal injuries.