Publications by authors named "Hao Hua Wu"

Background Context: Racial and ethnic minorities are underrepresented among healthcare providers in the United States (US).

Purpose: This study analyzed the training pathway of underrepresented groups in spine surgery relative to earlier stages of training and the US population.

Study Design/setting: This was a cross-sectional analysis of medical students, orthopaedic surgery residents, and spine surgery fellows at accredited training programs (2014 to 2024).

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Background: Patients increasingly turn to large language models (LLMs) and social media platforms for medical advice. The accuracy of these sources, particularly compared to peer-reviewed clinical practice guidelines, remains poorly characterized.

Materials And Methods: This cross-sectional study evaluated the perceived accuracy of spine-related medical advice generated by ChatGPT (ChatGPT (OpenAI, powered by GPT-4, San Francisco, CA, USA), TikTok (Los Angeles, CA, USA), and the North American Spine Society (NASS) clinical practice guidelines.

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Background: Endoscopic spine surgery is a minimally invasive technique that can treat spinal conditions while resulting in less pain and faster recovery than alternative techniques. However, achieving precise navigation is challenging without significant radiation exposure and increased surgical times. Fluoroscopy-based 2-dimensional navigation (2DNAV) is an emerging technology that offers real-time navigation using intraoperative fluoroscopy.

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Study Design: A retrospective cohort study.

Purpose: We present data assessing the differences in 30-day morbidity, mortality, and postoperative complications between the two surgical remedy options.

Overview Of Literature: The choice between decompression with fusion or decompression alone for the management of cervical spondylotic myelopathy (CSM) remains controversial.

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Background: A literature review and meta-analysis were conducted on studies comparing posterior fixation and fusion (PFF) and combined anterior and posterior fixation and fusion (CAPFF) for type B and C thoracolumbar injuries to determine the superior technique.

Methods: A search of PubMed, Ovid Medline, Scopus, and the Cochrane Central Register was conducted from inception to September 2023. Randomized controlled trials and observational studies comparing PFF and CAPFF for B and C thoracolumbar injuries in adults were included.

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Background: Although posterior lumbar fusions (PLFs) have risen in popularity due to minimally invasive techniques and favorable outcomes, complications still arise. Studies show relatively constant rates of postoperative complications from 2006 to 2016, but there are limited studies evaluating outcomes after 2016. Consequently, we aim to investigate trends in postoperative complications for PLFs from 2009 to 2022.

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Study Design: A retrospective cohort study.

Purpose: To assess differences in 30-day morbidity and mortality and postoperative complications between two surgical treatment options.

Overview Of Literature: The choice of decompression with fusion or decompression alone for the management of degenerative spondylolisthesis (DS) is controversial.

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Background Context: Endoscopic spine surgery (ESS) is rapidly emerging as a viable minimally invasive technique to successfully treat symptomatic degenerative spinal conditions. Widespread adoption has been limited in part due to the learning curve.

Purpose: To systematically review the learning curve for uniportal and biportal ESS and compare the 2 techniques.

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Background Context: Sex diversity in the spine surgery workforce remains limited. Accelerated efforts to recruit more female trainees into spine surgery fellowship training may help promote diversity and inclusion in the emerging spine surgery workforce.

Purpose: This study assessed the representation of female trainees in spine surgery fellowship training and program factors associated with greater sex diversity among fellows.

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Introduction: Spondylodiscitis (SD) is an infection of the intervertebral disc with involvement of the adjacent vertebral bodies. Diagnostic tests with CT-guided biopsy only provide a positive yield in 14%-48% of cases. Percutaneous endoscopic debridement and drainage (PEDD) has recently shown promise in the treatment of spondylodiscitis.

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Background: Pediatric fractures are common in Malawi, and surgical care, when needed, remains inaccessible to many. Understanding which children in Malawi receive surgery or nonsurgical treatment would help set priorities for trauma system development.

Methods: We used multivariate logistic regression to evaluate associations between surgical treatment and age, sex, school enrollment, injury mechanism, fracture type, open fracture, referral status, hospital of presentation, delayed presentation (≥2 days), healthcare provider, and inpatient vs outpatient treatment.

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Background: Endoscopic spine surgery has recently grown in popularity due to the potential benefits of reduced pain and faster recovery time as compared to open surgery. Biportal spinal endoscopy has been successfully applied to lumbar disc herniations and lumbar spinal stenosis. Obesity is associated with increased risk of complications in spine surgery.

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Study Design: Retrospective.

Objective: We utilized the NIH National COVID Cohort Collaborative (N3C) database to characterize the risk profile of patients undergoing spine surgery during multiple time windows following the COVID-19 infection.

Summary Of Background Data: While the impact of COVID-19 on various organ systems is well documented, there is limited knowledge regarding its effect on perioperative complications following spine surgery or the optimal timing of surgery after an infection.

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Article Synopsis
  • Identifying malnourished and at-risk patients is essential in preoperative evaluations for all patients, as malnutrition can significantly impact recovery.
  • Malnutrition is characterized by insufficient energy intake and symptoms like weight loss and muscle atrophy, leading to poorer surgical outcomes.
  • Interventions such as nutrition consultations and perioperative supplementation with amino acids and micronutrients can help improve recovery for malnourished patients.
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Purpose: To assess direct costs and risks associated with revision operations for distal junctional kyphosis/failure (DJK) following thoracic posterior spinal instrumented fusions (TPSF) for adolescent idiopathic scoliosis (AIS).

Methods: Children who underwent TPSF for AIS by a single surgeon (2014-2020) were reviewed. Inclusion criteria were minimum follow-up of 2 years, thoracolumbar posterior instrumented fusion with a lower instrumented vertebra (LIV) cranial to L2.

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Background: Femoral shaft fractures are common in Malawi, with an annual incidence of 44 per 100,000 people. Inadequate treatment and delayed presentation often result in functional, biopsychosocial, and financial challenges for patients. The purpose of this study was to examine the socioeconomic consequences of femoral shaft fractures for patients in Malawi.

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Study Design: Retrospective comparative study.

Objective: To compare patient-reported physical activity between anterior thoracic vertebral body tethering and posterior lumbar spine tethering (ATVBT/PLST) and posterior spinal instrumentation and fusion (PSIF) with minimum 2 year follow-up.

Methods: Consecutive skeletally immature patients with idiopathic scoliosis and a thoracic and lumbar curve magnitude ≥40° who underwent either ATVBT/PLST or PSIF from 2015-2019 were included.

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To avoid the high rate of complications associated with the surgical management of adult spinal deformity, it is important to recognize and avoid three major pitfalls. The first is patient selection and determining which cases are appropriately indicated. The second is optimizing modifiable medical issues that can lead to a poor outcome, such as smoking, vitamin D deficiency, nutritional status, and poor bone quality.

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Objective: Surgeon scientists remain underrepresented among recipients of National Institutes of Health (NIH) grants despite their unique ability to perform translational research. This study elucidates the portfolio of NIH grants awarded for degenerative spine diseases and the role of spine surgeons in this portfolio.

Methods: The most common diagnoses and surgical procedures for degenerative spine diseases were queried on the NIH Research Portfolio Online Reporting Tools Expenditures and Results (RePORTER) database (2011-2021).

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Background And Context:  In patients with adolescent idiopathic scoliosis (AIS) of main thoracic and lumbar spine regions, combined anterior thoracic vertebral body tethering and posterior lumbar spine tethering (ATVBT/PLST) is a novel non-fusion treatment option for growth modulation and conservation of motion.

Methods:  Fourteen patients with AIS who underwent ATVBT/PLST with at least 2-year follow-up were included. Primary outcomes included quality of life as assessed by SRS-22 instruments, radiographic analysis, and revision operations.

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Purpose: While posterior spinal instrumentation and fusion (PSIF) for severe adolescent idiopathic scoliosis (AIS) is the gold standard, anterior vertebral body tethering (AVBT) is becoming an alternative for select cases. Several studies have compared technical outcomes for these two procedures, but no studies have compared post-operative pain and recovery.

Methods: In this prospective cohort, we evaluated patients who underwent AVBT or PSIF for AIS for a period of 6 weeks after operation.

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Background: Correcting adolescent idiopathic scoliosis (AIS) without fusion can be achieved with anterior vertebral body tethering (AVBT). However, little is known about the perioperative outcomes, pain control, and clinical outcomes in patients undergoing AVBT compared with instrumented posterior spinal fusion (IPSF).

Methods: In this retrospective cohort study, we compared pediatric patients with AIS who underwent either AVBT or IPSF.

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