: Although digital cognitive behavioral therapy (dCBT) is considered effective for anxiety disorders, there is considerable heterogeneity in its efficacy across studies, and its varied treatment content and clinical components may explain such heterogeneity. : This review aimed to identify the efficacy of digital cognitive behavioral therapy for panic disorder and agoraphobia, and examine whether applying relevant clinical components of interoceptive exposure, inhibitory-learning-based exposure, and personalization of treatment enhances its efficacy. : Randomized controlled trials of dCBT for panic disorder and agoraphobia with passive or active controls were identified from OVID Medline, Embase, Cochrane Library, and PsycINFO.
View Article and Find Full Text PDFIntroduction: Electroencephalographic (EEG) abnormalities, such as increased theta power, have been proposed as biomarkers for neurocognitive disorders. Advancements in amyloid positron emission tomography (PET) imaging have enhanced our understanding of the pathology of neurocognitive disorders, such as amyloid deposition. However, much remains unknown regarding the relationship between regional amyloid deposition and EEG abnormalities.
View Article and Find Full Text PDFArch Gerontol Geriatr
April 2025
Background: Long-term health effects of adverse childhood experiences (ACEs) include cognitive decline that occurs later in life. Subjective cognitive decline (SCD), recognized as an early indicator of Alzheimer's disease, may present an essential period for intervention in populations with ACEs.
Objective: This review aims to explore the associations between ACEs and SCD, while examining the potential moderating effects of sociodemographic factors METHODS: A systematic search of four databases (Medline, PsycINFO, CINAHL, and Web of Science) was conducted from inception to July 2024.
Psychiatry Investig
July 2024
Objective: The abuse of prescription drugs and over-the-counter medicines has been a major issue addressed as a serious public health problem worldwide. This study explored factors contributing to substance abuse in Korea by examining the status of substance abuse among Korean adults and evaluating their knowledge, attitudes, and intentions toward substance abuse.
Methods: Data were collected online from a sample of participants 19 years old or older from May 20 to June 1, 2020 (n=1,020).
Clin Psychopharmacol Neurosci
February 2024
Objective: : Insomnia is associated with elevated high-frequency electroencephalogram power in the waking state. Although affective symptoms (e.g.
View Article and Find Full Text PDFCompr Psychiatry
February 2024
Background: Personalization is considered an important principle in virtual reality (VR) exposure therapy. We aimed to identify whether personalized VR exposure could provoke increased anxiety in patients with panic disorder and agoraphobia as it is considered the first step in successful treatment for anxiety.
Methods: We performed a double-arm, one-day preliminary study among 28 patients with panic disorder and agoraphobia.
Front Psychol
October 2023
In South Korea, anti-feminism is now rapidly spreading online among young men, who have started to identify themselves as a social minority or "victims" of female power. Despite its ramifications, theoretically, anti-feminism is indistinct from the racism and sexism of White men that emerged more than half a century ago. In view of this, it shares the same root as typical modern racism or sexism, although it appears to be a novel phenomenon.
View Article and Find Full Text PDFBackground: Most findings on the pathophysiology of alcoholism are based on studies using resting-state electroencephalography (EEG). There are few studies on cue-induced craving and on its utility as an electrophysiological index. We examined quantitative EEG (qEEG) activities in alcoholics and social drinkers exposed to video cues and compared their association with subjective alcohol craving and other related psychiatric symptoms, including anxiety and depression.
View Article and Find Full Text PDFBackground: Cardiorespiratory fitness (CRF) is a fundamental component of physical fitness. While maximal oxygen uptake (VOmax) is the gold standard for quantifying CRF, standard maximal exercise tests using direct measurements VOmax are dependent on the availability of laboratory equipment, and thereby expensive and time consuming. Recently, an equation was formulated to indirectly estimate VOmax using the YMCA 3-minute step test.
View Article and Find Full Text PDFStudy Question: Is the Transmembrane BAX Inhibitor Motif-6 (TMBIM6) involved in the molecular mechanism by which cisplatin causes reproductive toxicity?
Summary Answer: TMBIM6 protects against cisplatin-induced testicular toxicity through up-regulation of heme oxygenase-1 (HO-1),-which maintains the levels of steroidogenic enzymes by decreaseing oxidative stress in the endoplasmic reticulum (ER).
What Is Known Already: Testosterone production is highly suppressed as a main complication of cisplatin (cis-diamminedichloroplatinum) anticancer therapy.
Study Design, Size, Duration: Groups of seven wild type or Tmbim6 KO C57BL/6J mice were given a single i.
BMC Complement Altern Med
August 2016
Background: Curcumin, a major active component of turmeric, has previously been reported to alleviate liver damage. Here, we investigated the mechanism by which turmeric and curcumin protect the liver against carbon tetrachloride (CCl4)-induced injury in rats. We hypothesized that turmeric extract and curcumin protect the liver from CCl4-induced liver injury by reducing oxidative stress, inhibiting lipid peroxidation, and increasing glutathione peroxidase activation.
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